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Protein
Submitted name:

Nuclear orphan receptor ROR-beta

Gene

RORB

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi7 – 82Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-GGA-383280. Nuclear Receptor transcription pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear orphan receptor ROR-betaImported
Gene namesi
Name:RORBImported
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome Z

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSGALG00000015150.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000024400.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 82Nuclear receptor DNA-bindingInterPro annotationAdd BLAST76

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili90 – 114Sequence analysisAdd BLAST25

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4216. Eukaryota.
ENOG410XUGR. LUCA.
GeneTreeiENSGT00870000136388.
HOGENOMiHOG000010200.
HOVERGENiHBG106848.
KOiK08533.
OMAiCTLHTEE.
OrthoDBiEOG091G0649.

Family and domain databases

Gene3Di1.10.565.10. 3 hits.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR003079. ROR_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01293. RORNUCRECPTR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q98934-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAQIEVIPC KICGDKSSGI HYGVITCEGC KGFFRRSQQN NASYSCPRQR
60 70 80 90 100
NCLIDRTNRN RCQHCRLQKC LALGMSRDAV KFGRMSKKQR DSLYAEVQKH
110 120 130 140 150
QQRLQEQRQQ QSGEAEALAR VYSNSISNGL GNLNNETGST YSNGHVIDLP
160 170 180 190 200
KSEGYYNVDS AQPSPDQSGL DMTGIKQIKQ EPIYDLTSVP NLFTYSSFNN
210 220 230 240 250
GQLAPGISMT EIDRIAQNII KSHLETCQYT MEELHQLAWQ THTYEEIKVY
260 270 280 290 300
QSKTREALWQ QCAIQITHAI QYVVEFAKRI TGFMELCQND QILLLKSGCL
310 320 330 340 350
EVVLVRMCRA FNPLNNTVLF EGKYGGMQMF KALGSDDLVN EAFDFAKNLC
360 370 380 390 400
SLQLTEEEIA LFSSAVLISP DRAWLIEPRK VQKLQEKIYF ALQHVIQKNH
410 420 430 440 450
LDDETLTKLI AKIPTITALC NLHGEKLQVF KQSHPDIVNT LFPPLYKELF

NPDSTTGCK
Length:459
Mass (Da):52,172
Last modified:February 1, 1997 - v1
Checksum:iB4A6E2A760E36A79
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC186542 Genomic DNA. No translation available.
AC187587 Genomic DNA. No translation available.
KJ465914 mRNA. Translation: AHX99542.1.
Y08638 mRNA. Translation: CAA69928.1.
RefSeqiNP_990424.1. NM_205093.1.
UniGeneiGga.581.

Genome annotation databases

EnsembliENSGALT00000024445; ENSGALP00000024399; ENSGALG00000015150.
GeneIDi395980.
KEGGigga:395980.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC186542 Genomic DNA. No translation available.
AC187587 Genomic DNA. No translation available.
KJ465914 mRNA. Translation: AHX99542.1.
Y08638 mRNA. Translation: CAA69928.1.
RefSeqiNP_990424.1. NM_205093.1.
UniGeneiGga.581.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000024400.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000024445; ENSGALP00000024399; ENSGALG00000015150.
GeneIDi395980.
KEGGigga:395980.

Organism-specific databases

CTDi6096.

Phylogenomic databases

eggNOGiKOG4216. Eukaryota.
ENOG410XUGR. LUCA.
GeneTreeiENSGT00870000136388.
HOGENOMiHOG000010200.
HOVERGENiHBG106848.
KOiK08533.
OMAiCTLHTEE.
OrthoDBiEOG091G0649.

Enzyme and pathway databases

ReactomeiR-GGA-383280. Nuclear Receptor transcription pathway.

Gene expression databases

BgeeiENSGALG00000015150.

Family and domain databases

Gene3Di1.10.565.10. 3 hits.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR003079. ROR_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01293. RORNUCRECPTR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ98934_CHICK
AccessioniPrimary (citable) accession number: Q98934
Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: February 15, 2017
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.