Q98924 (HXA9_CHICK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Homeobox protein Hox-A9

Gene names

Name:

HOXA9

Organism

Gallus gallus (Chicken)

Taxonomic identifier

9031 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	169 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location	Nucleus.
Sequence similarities	Belongs to the Abd-B homeobox family. Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Domain	Homeobox
Ligand	DNA-binding
Molecular function	Developmental protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 169	›169	Homeobox protein Hox-A9		PRO_0000200083
Regions
	DNA binding	103 – 162	60	Homeobox
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	Q98924 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 9D74877543924B87	FASTA	169	19,668
	10 20 30 40 50 60 DGRYMRSWLE PVPGSLSFPG LPTSRHYGIK PEPLAARRGD CTTFDTHTLS LSDLPCGSPP 70 80 90 100 110 120 VDRDKQSHEG AFSENNGESE ANGEKPHIDP NNPAANWLHA RSTRKKRCPY TKHQTLELEK 130 140 150 160 EFLFNMYLTR DRRYEVARLL NLTERQVKIW FQNRRMKMKK INKDRAKDE

References

[1]	"Temporal colinearity in expression of anterior Hox genes in developing chick embryos." Gaunt S.J., Strachan L. Dev. Dyn. 207:270-280(1996) [PubMed: 8922526] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Embryo.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X97750 mRNA. Translation: CAA66331.1.
IPI	IPI00583350.
UniGene	Gga.649.
3D structure databases
ProteinModelPortal	Q98924.
SMR	Q98924. Positions 91-167.
ModBase	Search...
Protein-protein interaction databases
STRING	Q98924.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	veNOG15381.
GeneTree	ENSGT00560000076560.
HOGENOM	HBG714137.
HOVERGEN	HBG016849.
InParanoid	Q98924.
Family and domain databases
InterPro	IPR001356. Homeobox. IPR017970. Homeobox_CS. IPR020479. Homeobox_eu. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. IPR006711. Hox9_activation_N. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
Pfam	PF00046. Homeobox. 1 hit. PF04617. Hox9_act. 1 hit. [Graphical view]
PRINTS	PR00024. HOMEOBOX.
SMART	SM00389. HOX. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HXA9_CHICK

Accession

Primary (citable) accession number: Q98924

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	December 14, 2011
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program