Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q98924 (HXA9_CHICK) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Homeobox protein Hox-A9
Gene names
Name:HOXA9
OrganismGallus gallus (Chicken)
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Protein attributes

Sequence length169 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular location

Nucleus.

Sequence similarities

Belongs to the Abd-B homeobox family.

Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainHomeobox
   LigandDNA-binding
   Molecular functionDevelopmental protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processtranscription, DNA-dependent

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionsequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 169›169Homeobox protein Hox-A9
PRO_0000200083

Regions

DNA binding103 – 16260Homeobox

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
Q98924 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 9D74877543924B87

FASTA16919,668
        10         20         30         40         50         60 
DGRYMRSWLE PVPGSLSFPG LPTSRHYGIK PEPLAARRGD CTTFDTHTLS LSDLPCGSPP 

        70         80         90        100        110        120 
VDRDKQSHEG AFSENNGESE ANGEKPHIDP NNPAANWLHA RSTRKKRCPY TKHQTLELEK 

       130        140        150        160 
EFLFNMYLTR DRRYEVARLL NLTERQVKIW FQNRRMKMKK INKDRAKDE 

« Hide

References

[1]"Temporal colinearity in expression of anterior Hox genes in developing chick embryos."
Gaunt S.J., Strachan L.
Dev. Dyn. 207:270-280(1996) [PubMed: 8922526] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Embryo.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X97750 mRNA. Translation: CAA66331.1.
IPIIPI00583350.
UniGeneGga.649.

3D structure databases

ProteinModelPortalQ98924.
SMRQ98924. Positions 91-167.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ98924.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGveNOG15381.
GeneTreeENSGT00560000076560.
HOGENOMHBG714137.
HOVERGENHBG016849.
InParanoidQ98924.

Family and domain databases

InterProIPR001356. Homeobox.
IPR017970. Homeobox_CS.
IPR020479. Homeobox_eu.
IPR009057. Homeodomain-like.
IPR012287. Homeodomain-rel.
IPR006711. Hox9_activation_N.
[Graphical view]
Gene3DG3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
PfamPF00046. Homeobox. 1 hit.
PF04617. Hox9_act. 1 hit.
[Graphical view]
PRINTSPR00024. HOMEOBOX.
SMARTSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMSSF46689. Homeodomain_like. 1 hit.
PROSITEPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHXA9_CHICK
AccessionPrimary (citable) accession number: Q98924
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: December 14, 2011
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

Vertebrate homeotic Hox proteins

Nomenclature of vertebrate homeotic Hox proteins and list of entries

SIMILARITY comments

Index of protein domains and families