Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q988D3

- Q988D3_RHILO

UniProt

Q988D3 - Q988D3_RHILO

Protein
Submitted name:

2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase

Gene

mlr6788

Organism
Rhizobium loti (strain MAFF303099) (Mesorhizobium loti)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Oct 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei54 – 541FAD; via amide nitrogen and carbonyl oxygenImported
    Binding sitei106 – 1061FADImported
    Binding sitei130 – 1301FAD; via amide nitrogen and carbonyl oxygenImported
    Binding sitei156 – 1561FAD; via carbonyl oxygenImported
    Binding sitei181 – 1811FADImported
    Binding sitei288 – 2881FADImported

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi21 – 222FADImported
    Nucleotide bindingi41 – 422FADImported
    Nucleotide bindingi295 – 3028FADImported

    GO - Molecular functioni

    1. nucleotide binding Source: UniProtKB-KW
    2. oxidoreductase activity Source: InterPro

    Keywords - Ligandi

    FADImported, Flavoprotein, Nucleotide-bindingImported

    Enzyme and pathway databases

    BioCyciMLOT266835:GJ9L-5382-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenaseImported
    Gene namesi
    Ordered Locus Names:mlr6788Imported
    OrganismiRhizobium loti (strain MAFF303099) (Mesorhizobium loti)Imported
    Taxonomic identifieri266835 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
    ProteomesiUP000000552: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi266835.mlr6788.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3ALJX-ray1.48A1-379[»]
    3ALLX-ray1.78A/B1-379[»]
    3ALMX-ray1.77A/B1-379[»]
    3GMBX-ray2.10A/B1-379[»]
    3GMCX-ray2.10A/B1-379[»]
    4GF7X-ray1.58A1-379[»]
    4H2NX-ray2.30A1-379[»]
    4H2PX-ray1.98A/B/C/D1-379[»]
    4H2QX-ray1.50A1-379[»]
    4H2RX-ray2.47A/B1-379[»]
    4JY2X-ray1.94A/B1-379[»]
    4JY3X-ray1.77A/B1-379[»]
    ProteinModelPortaliQ988D3.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ988D3.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000000640.
    KOiK18071.
    OMAiCNENELY.
    OrthoDBiEOG6J48MG.

    Family and domain databases

    InterProiIPR002938. mOase_FAD-bd.
    IPR003042. Rng_hydrolase-like.
    [Graphical view]
    PfamiPF01494. FAD_binding_3. 1 hit.
    [Graphical view]
    PRINTSiPR00420. RNGMNOXGNASE.

    Sequencei

    Sequence statusi: Complete.

    Q988D3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MANVNKTPGK TRRAEVAGGG FAGLTAAIAL KQNGWDVRLH EKSSELRAFG    50
    AGIYLWHNGL RVLEGLGALD DVLQGSHTPP TYETWMHNKS VSKETFNGLP 100
    WRIMTRSHLH DALVNRARAL GVDISVNSEA VAADPVGRLT LQTGEVLEAD 150
    LIVGADGVGS KVRDSIGFKQ DRWVSKDGLI RLIVPRMKKE LGHGEWDNTI 200
    DMWNFWPRVQ RILYSPCNEN ELYLGLMAPA ADPRGSSVPI DLEVWVEMFP 250
    FLEPCLIEAA KLKTARYDKY ETTKLDSWTR GKVALVGDAA HAMCPALAQG 300
    AGCAMVNAFS LSQDLEEGSS VEDALVAWET RIRPITDRCQ ALSGDYAANR 350
    SLSKGNMFTP AALEAARYDP LRRVYSWPQ 379
    Length:379
    Mass (Da):41,748
    Last modified:October 1, 2001 - v1
    Checksum:i297E85523850E499
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000012 Genomic DNA. Translation: BAB53017.1.
    RefSeqiNP_107231.1. NC_002678.2.
    WP_010914327.1. NC_002678.2.

    Genome annotation databases

    EnsemblBacteriaiBAB53017; BAB53017; BAB53017.
    GeneIDi1229886.
    KEGGimlo:mlr6788.
    PATRICi22485043. VBIMesLot2464_5401.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000012 Genomic DNA. Translation: BAB53017.1 .
    RefSeqi NP_107231.1. NC_002678.2.
    WP_010914327.1. NC_002678.2.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3ALJ X-ray 1.48 A 1-379 [» ]
    3ALL X-ray 1.78 A/B 1-379 [» ]
    3ALM X-ray 1.77 A/B 1-379 [» ]
    3GMB X-ray 2.10 A/B 1-379 [» ]
    3GMC X-ray 2.10 A/B 1-379 [» ]
    4GF7 X-ray 1.58 A 1-379 [» ]
    4H2N X-ray 2.30 A 1-379 [» ]
    4H2P X-ray 1.98 A/B/C/D 1-379 [» ]
    4H2Q X-ray 1.50 A 1-379 [» ]
    4H2R X-ray 2.47 A/B 1-379 [» ]
    4JY2 X-ray 1.94 A/B 1-379 [» ]
    4JY3 X-ray 1.77 A/B 1-379 [» ]
    ProteinModelPortali Q988D3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 266835.mlr6788.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB53017 ; BAB53017 ; BAB53017 .
    GeneIDi 1229886.
    KEGGi mlo:mlr6788.
    PATRICi 22485043. VBIMesLot2464_5401.

    Phylogenomic databases

    HOGENOMi HOG000000640.
    KOi K18071.
    OMAi CNENELY.
    OrthoDBi EOG6J48MG.

    Enzyme and pathway databases

    BioCyci MLOT266835:GJ9L-5382-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q988D3.

    Family and domain databases

    InterProi IPR002938. mOase_FAD-bd.
    IPR003042. Rng_hydrolase-like.
    [Graphical view ]
    Pfami PF01494. FAD_binding_3. 1 hit.
    [Graphical view ]
    PRINTSi PR00420. RNGMNOXGNASE.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MAFF303099Imported.
    2. "Structure of the PLP degradative enzyme 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti MAFF303099 and its mechanistic implications."
      McCulloch K.M., Mukherjee T., Begley T.P., Ealick S.E.
      Biochemistry 48:4139-4149(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS).
    3. "Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase."
      Kobayashi J., Yoshida H., Yoshikane Y., Kamitori S., Yagi T.
      Submitted (AUG-2010) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.78 ANGSTROMS) IN COMPLEX WITH FAD.
    4. "Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase."
      Kobayashi J., Yoshida H., Mikami B., Hayashi H., Kamitori S., Sawa Y., Yagi T.
      Submitted (AUG-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.58 ANGSTROMS) IN COMPLEX WITH FAD.
    5. "Crystal structure of 2-Methyl-3-hydroxypyridiine-5-carboxylic acid oxygenase."
      Kobayashi J., Yoshida H., Mikami B., Hayashi H., Kamitori S., Yagi T.
      Submitted (SEP-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) IN COMPLEX WITH FAD.
    6. "Crystal structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid oxygenase."
      Kobayashi J., Yoshida H., Mikami B., Hayashi H., Kamitori S., Yagi T.
      Submitted (SEP-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.47 ANGSTROMS) IN COMPLEX WITH FAD.
    7. "Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase."
      Kobayashi J., Yoshida H., Mikami B., Hayashi H., Kamitori S., Yagi T.
      Submitted (SEP-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) IN COMPLEX WITH FAD.
    8. "Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase."
      Kobayashi J., Yoshida H., Kamitori S., Hayashi H., Mizutani K., Takahashi N., Mikami B., Yagi T.
      Submitted (MAR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.94 ANGSTROMS).

    Entry informationi

    Entry nameiQ988D3_RHILO
    AccessioniPrimary (citable) accession number: Q988D3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2001
    Last sequence update: October 1, 2001
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3