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Protein
Submitted name:

Homeodomain protein Nkx2.3

Gene

nkx2.3

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Homeodomain protein Nkx2.3Imported
Submitted name:
NK2 transcription factor related 3Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:nkx2.3Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 13

Organism-specific databases

ZFINiZDB-GENE-990415-178. nkx2.3.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000039095.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000057093.

Structurei

3D structure databases

SMRiQ98871. Positions 142-207.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini140 – 20061Homeobox DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains homeobox DNA-binding domain.SAAS annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotationImported

Phylogenomic databases

eggNOGiKOG0842. Eukaryota.
ENOG410XR21. LUCA.
GeneTreeiENSGT00840000129671.
HOGENOMiHOG000231923.
HOVERGENiHBG006689.
KOiK09343.
OMAiSCMLAGR.
OrthoDBiEOG091G0LZ2.
PhylomeDBiQ98871.
TreeFamiTF351204.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q98871-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMLPSPVTST PFSVKDILKL EQQTRQLQSL HPASHHAQLH PELQDRFQAP
60 70 80 90 100
SSCFLGGGDS PGFSDNEEKM SFLNSLSMQD SLVESSLSPP MFVHPALGHV
110 120 130 140 150
DTKLEDELED HETKSCGAIL RTPECEAEVH SDTERAQRQR TRRKPRVLFS
160 170 180 190 200
QAQVFELERR FKQQRYLSAP EREHLASTLK LTSTQVKIWF QNRRYKCKRQ
210 220 230 240 250
RQDKTLEMAG HHHPPPPRRV AVPVLVRDGK PCLTGSQSYN TTYAVNPGPY
260 270 280 290 300
TYNGYSSYNN AAYTNPYSCT YPSLPPLPAN TSTNALMSMS LNNLGTYSQP
310 320
QTSQGTPVSA CQGTLQGIRA W
Length:321
Mass (Da):36,093
Last modified:February 1, 1997 - v1
Checksum:i3C45305A10029132
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU929568 Genomic DNA. No translation available.
U66571 mRNA. Translation: AAC05228.1.
BC066525 mRNA. Translation: AAH66525.2.
RefSeqiNP_571498.1. NM_131423.1.
UniGeneiDr.269.

Genome annotation databases

EnsembliENSDART00000057094; ENSDARP00000057093; ENSDARG00000039095.
GeneIDi30698.
KEGGidre:30698.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU929568 Genomic DNA. No translation available.
U66571 mRNA. Translation: AAC05228.1.
BC066525 mRNA. Translation: AAH66525.2.
RefSeqiNP_571498.1. NM_131423.1.
UniGeneiDr.269.

3D structure databases

SMRiQ98871. Positions 142-207.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000057093.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000057094; ENSDARP00000057093; ENSDARG00000039095.
GeneIDi30698.
KEGGidre:30698.

Organism-specific databases

CTDi30698.
ZFINiZDB-GENE-990415-178. nkx2.3.

Phylogenomic databases

eggNOGiKOG0842. Eukaryota.
ENOG410XR21. LUCA.
GeneTreeiENSGT00840000129671.
HOGENOMiHOG000231923.
HOVERGENiHBG006689.
KOiK09343.
OMAiSCMLAGR.
OrthoDBiEOG091G0LZ2.
PhylomeDBiQ98871.
TreeFamiTF351204.

Gene expression databases

BgeeiENSDARG00000039095.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ98871_DANRE
AccessioniPrimary (citable) accession number: Q98871
Secondary accession number(s): Q6NYN2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 127 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.