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Protein
Submitted name:

Myocyte enhancer factor 2D MEF2D

Gene

mef2d

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • heart formation Source: ZFIN
  • MAPK cascade Source: InterPro
  • positive regulation of transcription from RNA polymerase II promoter Source: ZFIN
  • skeletal muscle myosin thick filament assembly Source: ZFIN
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Myocyte enhancer factor 2D MEF2DImported
Gene namesi
Name:mef2dImported
Synonyms:mef2DImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-990415-164. mef2d.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ98870.
PRIDEiQ98870.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000115546.

Structurei

3D structure databases

ProteinModelPortaliQ98870.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 61MADS-boxInterPro annotationAdd BLAST61

Sequence similaritiesi

Contains 1 MADS-box domain.UniRule annotation

Phylogenomic databases

eggNOGiKOG0014. Eukaryota.
COG5068. LUCA.
HOGENOMiHOG000230620.
HOVERGENiHBG053944.
KOiK09262.
PhylomeDBiQ98870.

Family and domain databases

CDDicd00265. MADS_MEF2_like. 1 hit.
InterProiIPR022102. HJURP_C.
IPR033896. MADS_MEF2-like.
IPR002100. TF_MADSbox.
[Graphical view]
PfamiPF12347. HJURP_C. 1 hit.
PF00319. SRF-TF. 1 hit.
[Graphical view]
PRINTSiPR00404. MADSDOMAIN.
SMARTiSM00432. MADS. 1 hit.
[Graphical view]
SUPFAMiSSF55455. SSF55455. 1 hit.
PROSITEiPS00350. MADS_BOX_1. 1 hit.
PS50066. MADS_BOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q98870-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRKKIQIQR ITDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNH
60 70 80 90 100
SNKLFQYAST DMDKVLLKYT EYNEPHESRT NADIIEALNK KEHRDSESPD
110 120 130 140 150
PEEPFSLTPR TEEKYKKIDE EFDKMMQSYR LSSTVPAPTF SMPVTVPVSN
160 170 180 190 200
QSPLPFSNPS SLVTTSFVTS TLTDPRLLSP QQPQLQRNTV SPGLPQRPAS
210 220 230 240 250
AGALLGGDLN NSNGACPSPV ANGYVSARAS PGLLSVSNGN SMGKVVQAKS
260 270 280 290 300
PPPPSTQMAN SRKPDLRVIT SQSSKGLMQL TDEELELVSE NAQRLGTSQV
310 320 330 340 350
TQPLTTPVVS VATPSLLTPF SMPTAYNTEY QLTSADLTAL QAFTPSGALL
360 370 380 390 400
PGNMTTWQQQ QQPSVSQQPQ QQPSVSQQQT QQQQQQQQQP QQLTLASLSN
410 420 430 440 450
LVPVGTIPHG ATLTVNTNPS ISIKSEPVSP NRDRSTPSST PGAVGGVSGL
460 470 480 490 500
TVSQYPGTLR LEPTGRSPVD SISSNGSSYE GSDRDDSGQP RPPDFSSLGL
510 520
LRATGDQPAQ AEQQESANVK RMRLDTWVT
Length:529
Mass (Da):57,484
Last modified:February 1, 1997 - v1
Checksum:i89E672859EEC2A8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U66570 mRNA. Translation: AAC05227.1.
RefSeqiNP_571392.1. NM_131317.1.
UniGeneiDr.75103.

Genome annotation databases

GeneIDi30580.
KEGGidre:30580.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U66570 mRNA. Translation: AAC05227.1.
RefSeqiNP_571392.1. NM_131317.1.
UniGeneiDr.75103.

3D structure databases

ProteinModelPortaliQ98870.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000115546.

Proteomic databases

PaxDbiQ98870.
PRIDEiQ98870.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi30580.
KEGGidre:30580.

Organism-specific databases

CTDi4209.
ZFINiZDB-GENE-990415-164. mef2d.

Phylogenomic databases

eggNOGiKOG0014. Eukaryota.
COG5068. LUCA.
HOGENOMiHOG000230620.
HOVERGENiHBG053944.
KOiK09262.
PhylomeDBiQ98870.

Family and domain databases

CDDicd00265. MADS_MEF2_like. 1 hit.
InterProiIPR022102. HJURP_C.
IPR033896. MADS_MEF2-like.
IPR002100. TF_MADSbox.
[Graphical view]
PfamiPF12347. HJURP_C. 1 hit.
PF00319. SRF-TF. 1 hit.
[Graphical view]
PRINTSiPR00404. MADSDOMAIN.
SMARTiSM00432. MADS. 1 hit.
[Graphical view]
SUPFAMiSSF55455. SSF55455. 1 hit.
PROSITEiPS00350. MADS_BOX_1. 1 hit.
PS50066. MADS_BOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ98870_DANRE
AccessioniPrimary (citable) accession number: Q98870
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: November 30, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.