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Protein
Submitted name:

Myocyte enhancer factor 2C MEF2C

Gene

mef2ca

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • transcription regulatory region sequence-specific DNA binding Source: ZFIN

GO - Biological processi

  • bone morphogenesis Source: ZFIN
  • cardiac muscle cell development Source: ZFIN
  • cardiac muscle cell differentiation Source: ZFIN
  • cartilage morphogenesis Source: ZFIN
  • heart development Source: ZFIN
  • heart formation Source: ZFIN
  • positive regulation of transcription from RNA polymerase II promoter Source: ZFIN
  • skeletal muscle myosin thick filament assembly Source: ZFIN
  • transcription, DNA-templated Source: ZFIN
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Myocyte enhancer factor 2C MEF2CImported
Gene namesi
Name:mef2caImported
Synonyms:mef2CImported, mef2cImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-253. mef2ca.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ98869.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000015104.

Structurei

3D structure databases

ProteinModelPortaliQ98869.
SMRiQ98869. Positions 2-93.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 6161MADS-boxInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 MADS-box domain.UniRule annotation

Phylogenomic databases

eggNOGiKOG0014. Eukaryota.
COG5068. LUCA.
HOGENOMiHOG000230620.
HOVERGENiHBG053944.

Family and domain databases

InterProiIPR022102. HJURP_C.
IPR002100. TF_MADSbox.
[Graphical view]
PfamiPF12347. HJURP_C. 1 hit.
PF00319. SRF-TF. 1 hit.
[Graphical view]
PRINTSiPR00404. MADSDOMAIN.
SMARTiSM00432. MADS. 1 hit.
[Graphical view]
SUPFAMiSSF55455. SSF55455. 1 hit.
PROSITEiPS00350. MADS_BOX_1. 1 hit.
PS50066. MADS_BOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q98869-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRKKIQIAR IMDERNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS
60 70 80 90 100
TNKLFQYAST DMDKVLLKYT EYNEPHESRT NSDIVETLRK KGLNGCDSPD
110 120 130 140 150
IDAEDSGHSP ESEDKYRKIN EDIDLMISRQ RLCAIPQSNY DMPVSIPVSN
160 170 180 190 200
PNSLIYGHPG ASMGNPNLLP LTHPSLQRNS MSPGVTHRPP SAGNTGNGYG
210 220 230 240 250
NHRNSPGLLV SPGNMSKNLQ AKSPPSMNMS LSRKPDLRVL IPPGAKNTMP
260 270 280 290 300
SINQRISSSQ SAQSLSTPVV SVATPTLPGE VMGGYPSAIN TSYGTEYSLS
310 320 330 340 350
SGDLSSLSAF NSSASLHLGS MTGWPQNMQH SGLGHLGNCS SAQLCQSSAL
360 370 380 390 400
SLPSNQNLHI KSEPVSPPRD RASGTPGLYG VPQQTPLRQD SGRSPVDSLS
410 420 430 440
SCGSSYDGSD RDEHRANFHS PVGLMRAAEN ERQSPSVKRM RLSEAGWAS
Length:449
Mass (Da):48,646
Last modified:February 1, 1997 - v1
Checksum:i5A3E2CA9F49E719D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U66569 mRNA. Translation: AAC05226.1.
UniGeneiDr.3182.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U66569 mRNA. Translation: AAC05226.1.
UniGeneiDr.3182.

3D structure databases

ProteinModelPortaliQ98869.
SMRiQ98869. Positions 2-93.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000015104.

Proteomic databases

PaxDbiQ98869.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ZFINiZDB-GENE-980526-253. mef2ca.

Phylogenomic databases

eggNOGiKOG0014. Eukaryota.
COG5068. LUCA.
HOGENOMiHOG000230620.
HOVERGENiHBG053944.

Family and domain databases

InterProiIPR022102. HJURP_C.
IPR002100. TF_MADSbox.
[Graphical view]
PfamiPF12347. HJURP_C. 1 hit.
PF00319. SRF-TF. 1 hit.
[Graphical view]
PRINTSiPR00404. MADSDOMAIN.
SMARTiSM00432. MADS. 1 hit.
[Graphical view]
SUPFAMiSSF55455. SSF55455. 1 hit.
PROSITEiPS00350. MADS_BOX_1. 1 hit.
PS50066. MADS_BOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ98869_DANRE
AccessioniPrimary (citable) accession number: Q98869
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: May 11, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.