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Protein
Submitted name:

Dopamine D1B receptor

Gene

d1B

Organism
Anguilla anguilla (European freshwater eel) (Muraena anguilla)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Dopamine D1B receptorImported
Gene namesi
Name:d1BImported
OrganismiAnguilla anguilla (European freshwater eel) (Muraena anguilla)Imported
Taxonomic identifieri7936 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiAnguilliformesAnguillidaeAnguilla

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei40 – 6930HelicalSequence analysisAdd
BLAST
Transmembranei81 – 9818HelicalSequence analysisAdd
BLAST
Transmembranei118 – 13922HelicalSequence analysisAdd
BLAST
Transmembranei159 – 17921HelicalSequence analysisAdd
BLAST
Transmembranei213 – 23624HelicalSequence analysisAdd
BLAST
Transmembranei283 – 30422HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ98843.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini60 – 348289G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG106962.

Family and domain databases

InterProiIPR000497. Dopamine_D5_rcpt.
IPR000929. Dopamine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00566. DOPAMINED1BR.
PR00242. DOPAMINER.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q98843-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSPAKYLSV HETQSVPFFI GEIMWNTSES AEKTDGKKEL IVRTVTGCLL
60 70 80 90 100
SLLILWTLLG NILVCSAVLK FRHLRTKVTN IFIVSLAVSD LFVAVLVMPW
110 120 130 140 150
KAVAEVAGYW PFGPFCNIWV AFDIMCSTAS ILNLCIISVD RYWAISSPFR
160 170 180 190 200
YERKMTQRVA FVMISVTWTL SVLISFIPVQ LNWHKASDEE VWINGTSFGE
210 220 230 240 250
KSENCDSSLN REYAISSSLI SFYIPVAIMI VTYTRIYRIA QIQIRRISSL
260 270 280 290 300
ERAAEHAQSC RTNRLECQHH NTLKTSIKRE TKVFKTLSVI MGVFVCCWLP
310 320 330 340 350
FFILNCIVPF CDRPPTDHTA GLPCVSDTTF DVFVWFGWTN SSLNPIIYAF
360 370 380 390 400
NADFRKAFAS LLGCRNFCSR TPVETVNISN ELVSYNQDTL FHKEIVTAYV
410 420 430 440 450
NMIPNVVDCI DDNEDTFDRI SQFSHNNEIA TDSVCDLDDC EADICLDRLA

PFTPNGLH
Length:458
Mass (Da):51,942
Last modified:February 1, 1997 - v1
Checksum:iDF5A86EF77C6B3E7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62920 mRNA. Translation: AAC60070.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62920 mRNA. Translation: AAC60070.1.

3D structure databases

ProteinModelPortaliQ98843.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG106962.

Family and domain databases

InterProiIPR000497. Dopamine_D5_rcpt.
IPR000929. Dopamine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00566. DOPAMINED1BR.
PR00242. DOPAMINER.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Early emergence of three dopamine D1 receptor subtypes in vertebrates. Molecular phylogenetic, pharmacological, and functional criteria defining D1A, D1B, and D1C receptors in European eel Anguilla anguilla."
    Cardinaud B., Sugamori K.S., Coudouel S., Vincent J.D., Niznik H.B., Vernier P.
    J. Biol. Chem. 272:2778-2787(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ98843_ANGAN
AccessioniPrimary (citable) accession number: Q98843
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: May 11, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.