Q987X5 (UXUA_RHILO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Mannonate dehydratase
EC=4.2.1.8

Alternative name(s):
D-mannonate hydrolase

Gene names

Name:	uxuA
Ordered Locus Names:	mlr6866

Organism

Rhizobium loti (strain MAFF303099) (Mesorhizobium loti) [Complete proteome] [HAMAP]

Taxonomic identifier

266835 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Mesorhizobium

Protein attributes

Sequence length	394 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106
Sequence similarities	Belongs to the mannonate dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	mannonate dehydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 394	394	Mannonate dehydratase HAMAP MF_00106		PRO_0000170682

Sequences

	Sequence		Length	Mass (Da)
	Q987X5 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: EBE0BC1E8FFC4003	FASTA	394	44,543
	10 20 30 40 50 60 MEQCWRWYGP DDPVTLDHVR QAGATGVVSA LHHIYDGRAW PEADVLERKR IIEAAGLTWS 70 80 90 100 110 120 VVESIPVHNS FKIGAPERER YAGYYRDSIR TLATAGIKTI CYNFMPVVDW TRTDLMYRLP 130 140 150 160 170 180 TTGYALRFDA VDFAAYDLFV LQRKDGAASY TPARIAEAEK RLKALTSEQV DQIERNLIAG 190 200 210 220 230 240 LPATERKYDR DSFREALAEY DGIGPKELRD NLAWFLREII PVAEEEGVRM CIHPDDPPFS 250 260 270 280 290 300 LYGLPRVVST AQDARFILNA VDSPANGLTF CTGSYGTRAD NDIVAMVKEF ADRIHFVHLR 310 320 330 340 350 360 NITIEEDGSF YEAEHLEGGT DMAHVILALM QEEARRRKEG RADWRIPMRP DHGHLLADDI 370 380 390 GKKKINPGYS LIGRLKGLAE LRGIMRAVEK FGLA

References

[1]

"Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti." Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S., Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y., Nakayama S. , Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M., Tabata S. DNA Res. 7:331-338(2000) [PubMed: 11214968] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MAFF303099.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000012 Genomic DNA. Translation: BAB53075.1.
RefSeq	NP_107289.1. NC_002678.2.
3D structure databases
ProteinModelPortal	Q987X5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1229944.
GenomeReviews	Gene locus mlr6866 in contig BA000012_GR.
KEGG	mlo:mlr6866.
NMPDR	fig|266835.1.peg.5390.
PATRIC	22485167. VBIMesLot2464_5463.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG585927.
OMA	RPDHGHL.
ProtClustDB	PRK03906.
Family and domain databases
HAMAP	MF_00106. UxuA. [Tree]
InterPro	IPR004628. Man_deHydtase. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KO	K01686.
Pfam	PF03786. UxuA. 1 hit. [Graphical view]
PIRSF	PIRSF016049. Man_dehyd. 1 hit.
SUPFAM	SSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMs	TIGR00695. UxuA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UXUA_RHILO

Accession

Primary (citable) accession number: Q987X5

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2002
Last sequence update:	October 1, 2001
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program