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Protein

Glycine--tRNA ligase alpha subunit

Gene

glyQ

Organism
Rhizobium loti (strain MAFF303099) (Mesorhizobium loti)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine--tRNA ligase alpha subunitUniRule annotation (EC:6.1.1.14UniRule annotation)
Alternative name(s):
Glycyl-tRNA synthetase alpha subunitUniRule annotation
Short name:
GlyRSUniRule annotation
Gene namesi
Name:glyQUniRule annotation
Ordered Locus Names:mlr7434
OrganismiRhizobium loti (strain MAFF303099) (Mesorhizobium loti)
Taxonomic identifieri266835 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
Proteomesi
  • UP000000552 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000728581 – 314Glycine--tRNA ligase alpha subunitAdd BLAST314

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.UniRule annotation

Protein-protein interaction databases

STRINGi266835.mlr7434.

Structurei

3D structure databases

ProteinModelPortaliQ986B6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QIB. Bacteria.
COG0752. LUCA.
HOGENOMiHOG000264291.
KOiK01878.
OMAiLGSYYQF.
OrthoDBiPOG091H01SB.

Family and domain databases

CDDicd00733. GlyRS_alpha_core. 1 hit.
HAMAPiMF_00254. Gly_tRNA_synth_alpha. 1 hit.
InterProiIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamiPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSiPR01044. TRNASYNTHGA.
TIGRFAMsiTIGR00388. glyQ. 1 hit.
PROSITEiPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q986B6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTIEIPAHMH PSRSFQGLIL TLHNYWAAYG CVILQPYDME VGAGTFHPAT
60 70 80 90 100
TLRALGPKRW NAAYVQPSRR PKDGRYGENP NRLQHYYQYQ VILKPNPPNL
110 120 130 140 150
QELYLGSLAA IGVDPLLHDI RFVEDDWESP TLGAWGLGWE CWCDGMEVSQ
160 170 180 190 200
FTYFQQVCGI ECAPVAGELT YGLERLAMYV QGVDNVYDLN FNGREGADKV
210 220 230 240 250
TYGDVFLQAE QEYSRHNFEY ADTAMLLRHF EDAEAECKAL LDAGAPASND
260 270 280 290 300
NLPMHKMVFP AYDQCIKASH VFNLLDARGV ISVTERQSYI LRVRNLAKAC
310
GEAFLKTQAG GLAA
Length:314
Mass (Da):35,267
Last modified:October 1, 2001 - v1
Checksum:i74B2731D666A6B59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000012 Genomic DNA. Translation: BAB53537.1.

Genome annotation databases

EnsemblBacteriaiBAB53537; BAB53537; BAB53537.
KEGGimlo:mlr7434.
PATRICi22486113. VBIMesLot2464_5936.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000012 Genomic DNA. Translation: BAB53537.1.

3D structure databases

ProteinModelPortaliQ986B6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266835.mlr7434.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB53537; BAB53537; BAB53537.
KEGGimlo:mlr7434.
PATRICi22486113. VBIMesLot2464_5936.

Phylogenomic databases

eggNOGiENOG4107QIB. Bacteria.
COG0752. LUCA.
HOGENOMiHOG000264291.
KOiK01878.
OMAiLGSYYQF.
OrthoDBiPOG091H01SB.

Family and domain databases

CDDicd00733. GlyRS_alpha_core. 1 hit.
HAMAPiMF_00254. Gly_tRNA_synth_alpha. 1 hit.
InterProiIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamiPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSiPR01044. TRNASYNTHGA.
TIGRFAMsiTIGR00388. glyQ. 1 hit.
PROSITEiPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSYGA_RHILO
AccessioniPrimary (citable) accession number: Q986B6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2001
Last modified: November 2, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.