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Protein

Triplex capsid protein 2

Gene

TRX2

Organism
Human herpesvirus 8 type M
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Triplex capsid protein 2UniRule annotation
Gene namesi
Name:TRX2UniRule annotation
OrganismiHuman herpesvirus 8 type MImported
Taxonomic identifieri435895 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeGammaherpesvirinaeRhadinovirus

Subcellular locationi

  • Virion UniRule annotation
  • Host nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Capsid proteinUniRule annotation, Host nucleusUniRule annotation, Virion

Interactioni

Subunit structurei

Interacts with TRX1 and major capisd protein/MCP.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the herpesviridae TRX2 protein family.UniRule annotation

Family and domain databases

HAMAPiMF_04019. HSV_TRX2. 1 hit.
InterProiView protein in InterPro
IPR002690. Herpes_capsid_2.
PfamiView protein in Pfam
PF01802. Herpes_V23. 1 hit.

Sequencei

Sequence statusi: Complete.

Q98667-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALDKSIVVN FTSRLFADEL AALQSKIGSV LPLGDCHRLQ NIQALGLGCV
60 70 80 90 100
CSRETSPDYI QIMQYLSKCT LAVLEEVRPD SLRLTRMDPS DNLQIKNVYA
110 120 130 140 150
PFFQWDSNTQ LAVLPPFFSR KDSTIVLESN GFDLVFPMVV PQQLGHAILQ
160 170 180 190 200
QLLVYHIYSK ISAGAPDDVN MAELDLYTTN VSFMGRTYRL DVDNTDPRTA
210 220 230 240 250
LRVLDDLSMY LCILSALVPR GCLRLLTALV RHDRHPLTEV FEGVVPDEVT
260 270 280 290 300
RIDLDQLSVP DDITRMRVMF SYLQSLSSIF NLGPRLHVYA YSAETLAASC

WYSPR
Length:305
Mass (Da):34,373
Last modified:February 1, 1997 - v1
Checksum:i5C5D9E83C24902BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75698 Genomic DNA. Translation: AAC57107.1.

Similar proteinsi

Entry informationi

Entry nameiQ98667_HHV8
AccessioniPrimary (citable) accession number: Q98667
Secondary accession number(s): O12571
Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: September 27, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)