SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q985M5

- BETA_RHILO

UniProt

Q985M5 - BETA_RHILO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Oxygen-dependent choline dehydrogenase
Gene
betA, mll7609
Organism
Rhizobium loti (strain MAFF303099) (Mesorhizobium loti)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate By similarity.UniRule annotation

Catalytic activityi

Choline + acceptor = betaine aldehyde + reduced acceptor.UniRule annotation
Betaine aldehyde + NAD+ + H2O = betaine + NADH.UniRule annotation

Cofactori

FAD By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei466 – 4661 By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi5 – 3430FAD By similarity
Add
BLAST

GO - Molecular functioni

  1. betaine-aldehyde dehydrogenase activity Source: UniProtKB-EC
  2. choline dehydrogenase activity Source: UniProtKB-HAMAP
  3. flavin adenine dinucleotide binding Source: InterPro

GO - Biological processi

  1. glycine betaine biosynthetic process from choline Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein, NAD

Enzyme and pathway databases

BioCyciMLOT266835:GJ9L-6045-MONOMER.
UniPathwayiUPA00529; UER00385.

Names & Taxonomyi

Protein namesi
Recommended name:
Oxygen-dependent choline dehydrogenase (EC:1.1.99.1)
Short name:
CDH
Short name:
CHD
Alternative name(s):
Betaine aldehyde dehydrogenase (EC:1.2.1.8)
Short name:
BADH
Gene namesi
Name:betA
Ordered Locus Names:mll7609
OrganismiRhizobium loti (strain MAFF303099) (Mesorhizobium loti)
Taxonomic identifieri266835 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
ProteomesiUP000000552: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 550550Oxygen-dependent choline dehydrogenaseUniRule annotation
PRO_0000205593Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266835.mll7609.

Structurei

3D structure databases

ProteinModelPortaliQ985M5.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2303.
HOGENOMiHOG000139600.
KOiK00108.
OMAiLTDDYNG.
OrthoDBiEOG67HJQP.

Family and domain databases

HAMAPiMF_00750. Choline_dehydrogen.
InterProiIPR011533. BetA.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
PfamiPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsiTIGR01810. betA. 1 hit.
PROSITEiPS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q985M5-1 [UniParc]FASTAAdd to Basket

« Hide

MLEADFVIIG SGSAGSAMAY RLSEDGKHSV IVIEFGGSDI GPLIQMPSAL    50
SIPLNMSLYD WGFASEPEPH LGGRVLATPR GKVIGGSSSI NGMVYVRGHA 100
RDFDHWAEEG ATGWGFADVL PYFKRMEDND GGEDGWRGHG GPLHVQRGSR 150
KNPLYGAFVE AGRQAGFELT DDYNGSKQEG FGPMEQTISG GRRWSAASAY 200
LKPALKRKNV SLVKGFARRV IIENQRAIGV EIEAHKQIQV VKARREVIVA 250
ASSINSPKIL MLSGIGPAEH LRENGIAVVA DRPGVGRNLQ DHMELYIQQE 300
STKPITLNSV LNPFSKALIG AQWLFFKSGL GATNHFEAAA FVRSRAGVDY 350
PDIQYHFIPA AVRYDGKAAA KSHGFQAHVG PMRSKSRGSV TLRSPDPKAK 400
PVIRFNYMSH PDDWTEFRHC IRLTREIFGQ SAFDAFRGQE ISPGSHVQSD 450
DDLDVFIRDH AESAYHPCGT CKMGRADDVT SVVDPECRVI GVDGLRVADS 500
SIFPRVTNGN LNAPSIMTGE KASDHILGRT PLAPSNQEPW INPRWQVSDR 550
Length:550
Mass (Da):60,125
Last modified:October 1, 2001 - v1
Checksum:iB3FC4F94EA6B5E21
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000012 Genomic DNA. Translation: BAB54037.1.
RefSeqiNP_107892.1. NC_002678.2.

Genome annotation databases

EnsemblBacteriaiBAB54037; BAB54037; BAB54037.
GeneIDi1230547.
KEGGimlo:mll7609.
PATRICi22486421. VBIMesLot2464_6088.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000012 Genomic DNA. Translation: BAB54037.1 .
RefSeqi NP_107892.1. NC_002678.2.

3D structure databases

ProteinModelPortali Q985M5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 266835.mll7609.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB54037 ; BAB54037 ; BAB54037 .
GeneIDi 1230547.
KEGGi mlo:mll7609.
PATRICi 22486421. VBIMesLot2464_6088.

Phylogenomic databases

eggNOGi COG2303.
HOGENOMi HOG000139600.
KOi K00108.
OMAi LTDDYNG.
OrthoDBi EOG67HJQP.

Enzyme and pathway databases

UniPathwayi UPA00529 ; UER00385 .
BioCyci MLOT266835:GJ9L-6045-MONOMER.

Family and domain databases

HAMAPi MF_00750. Choline_dehydrogen.
InterProi IPR011533. BetA.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view ]
Pfami PF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsi TIGR01810. betA. 1 hit.
PROSITEi PS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MAFF303099.

Entry informationi

Entry nameiBETA_RHILO
AccessioniPrimary (citable) accession number: Q985M5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: October 1, 2001
Last modified: September 3, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi