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Q984K6

- PUR5_RHILO

UniProt

Q984K6 - PUR5_RHILO

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Rhizobium loti (strain MAFF303099) (Mesorhizobium loti)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMLOT266835:GJ9L-6315-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
Alternative name(s):
AIR synthaseUniRule annotation
AIRSUniRule annotation
Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
Gene namesi
Name:purMUniRule annotation
Ordered Locus Names:mll7962
OrganismiRhizobium loti (strain MAFF303099) (Mesorhizobium loti)
Taxonomic identifieri266835 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
ProteomesiUP000000552: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 369369Phosphoribosylformylglycinamidine cyclo-ligasePRO_0000148238Add
BLAST

Proteomic databases

PRIDEiQ984K6.

Interactioni

Protein-protein interaction databases

STRINGi266835.mll7962.

Structurei

3D structure databases

ProteinModelPortaliQ984K6.
SMRiQ984K6. Positions 22-359.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiGEATCEV.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741. AIRS.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q984K6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKRDTSQPK TGQPKTSKRR NGLTYAEAGV DIDAGNLMVE KIKPLVRATR
60 70 80 90 100
RPGADGEIGG FGGLFDLKAA GFTDPVLVAA NDGVGTKLKI AIDAGKHDTI
110 120 130 140 150
GIDLVAMCVN DIVVQGAEPL FFLDYFATGK LDPDQGAAIV GGIAEGCRQA
160 170 180 190 200
GCALIGGETA EMPGMYHGND YDLAGFAVGA AERGQLLPTD DIVEGDVLLG
210 220 230 240 250
LASSGLHSNG FSLVRRIVAA SGLAWSDPAP FNDEATLAEA LLEPTRIYVK
260 270 280 290 300
SILKAIRNTH GIKALAHITG GGFPENIPRV LPKDFSAELD LEAIDVPPVF
310 320 330 340 350
SWLAKTGGVA PEEMMRTFNC GVGMILAVAS GQAAQVAAVL QEAGETVTPI
360
GRIVPRRDAG VIYRGSIGL
Length:369
Mass (Da):38,418
Last modified:October 1, 2001 - v1
Checksum:i2DC3BA404506C81D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000012 Genomic DNA. Translation: BAB53624.1.
RefSeqiNP_108163.1. NC_002678.2.
WP_010915250.1. NC_002678.2.

Genome annotation databases

EnsemblBacteriaiBAB53624; BAB53624; BAB53624.
GeneIDi1230815.
KEGGimlo:mll7962.
PATRICi22486985. VBIMesLot2464_6369.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000012 Genomic DNA. Translation: BAB53624.1 .
RefSeqi NP_108163.1. NC_002678.2.
WP_010915250.1. NC_002678.2.

3D structure databases

ProteinModelPortali Q984K6.
SMRi Q984K6. Positions 22-359.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 266835.mll7962.

Proteomic databases

PRIDEi Q984K6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB53624 ; BAB53624 ; BAB53624 .
GeneIDi 1230815.
KEGGi mlo:mll7962.
PATRICi 22486985. VBIMesLot2464_6369.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi GEATCEV.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci MLOT266835:GJ9L-6315-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741. AIRS.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MAFF303099.

Entry informationi

Entry nameiPUR5_RHILO
AccessioniPrimary (citable) accession number: Q984K6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: October 1, 2001
Last modified: October 29, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3