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Protein

DNA polymerase

Gene

MC039L

Organism
Molluscum contagiosum virus subtype 1 (MOCV) (MCVI)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DNA-directed DNA polymeraseUniRule annotation, Nucleotidyltransferase, Transferase

Keywords - Biological processi

DNA replicationUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymeraseUniRule annotation (EC:2.7.7.7UniRule annotation)
Gene namesi
Name:MC039LImported
OrganismiMolluscum contagiosum virus subtype 1 (MOCV) (MCVI)Imported
Taxonomic identifieri10280 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeMolluscipoxvirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000000869 Componenti: Genome

Structurei

3D structure databases

ProteinModelPortaliQ98207.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 22DNAP_B_exo_NInterPro annotationAdd BLAST22
Domaini109 – 344DNA_pol_B_exo1InterPro annotationAdd BLAST236
Domaini345 – 472DNA_pol_B_3InterPro annotationAdd BLAST128
Domaini480 – 983DNA_pol_BInterPro annotationAdd BLAST504

Sequence similaritiesi

Belongs to the DNA polymerase type-B family.UniRule annotation

Phylogenomic databases

KOiK18964.

Family and domain databases

Gene3Di3.30.420.10. 2 hits.
3.90.1600.10. 2 hits.
InterProiIPR006172. DNA-dir_DNA_pol_B.
IPR017964. DNA-dir_DNA_pol_B_CS.
IPR006133. DNA-dir_DNA_pol_B_exonuc.
IPR006134. DNA-dir_DNA_pol_B_multi_dom.
IPR013617. DNA-dir_DNA_pol_B_vir_insert.
IPR023211. DNA_pol_palm_dom.
IPR013660. DNApol_B_exo_N.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF00136. DNA_pol_B. 1 hit.
PF08408. DNA_pol_B_3. 1 hit.
PF03104. DNA_pol_B_exo1. 1 hit.
PF08452. DNAP_B_exo_N. 1 hit.
[Graphical view]
PRINTSiPR00106. DNAPOLB.
SMARTiSM00486. POLBc. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 2 hits.
PROSITEiPS00116. DNA_POLYMERASE_B. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q98207-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEIRCLNWFE ARGEERALYL KAKTRAGDTL FVRFPHYYYY VVDGGTLSTL
60 70 80 90 100
APPPRAASAL GEFELACIDE TLARADALHA PTRPRSQLWL LEEAQPRQIA
110 120 130 140 150
GALLAEFMHI TWFFLRNEIE PNGCYRVPDA ELEPVCARCF HCAAPRRAFA
160 170 180 190 200
TRVPLFEVTH TYLFFDIECQ FDKKFPSVFS NPVSHISFCY VDRLGTEVRF
210 220 230 240 250
SLLNSDLLSE DSLRGCRRIA TPDEFALEPG VTFCSEVVLL QLTKRLLERH
260 270 280 290 300
FDFIVTFNGN NFDIRYVSNR LQLLTQSSVC FRLPDQREPV KLVIYERSLA
310 320 330 340 350
SHRGAGGMAN TSFHVNNNNG TIFFDLYTFI QKAERLDSYK LDSISKNVFH
360 370 380 390 400
CRARVLDAGA GECTLAGGPD ANAEDRLRLF CEVLQTGNYV TLDTVHVCRI
410 420 430 440 450
LGKRFFEHGF ALRVRCAESY APGSLCELAF GKDDVDLREL YRHYSLAAAL
460 470 480 490 500
EMERYCMHDA CLCKYLWSYY RVPSKIDAAA ATYLLPQCLA LEYRASTLIK
510 520 530 540 550
GPLLRLMLRE RVVYVRTQEP ARYTYGGGKV FLPRQKLFDT NVMVFDYNSL
560 570 580 590 600
YPNVCIFGNL SPETLVGVVA NAHRLDAEIN MQELRRRFPE PAFLHVLCEA
610 620 630 640 650
RARDGYSEIA VFDRRRQGII PKLLGTFMEQ RARYKALMRA ASSGLERTLY
660 670 680 690 700
DSMQYVYKVV ANSVYGLMGF YNSSLYSYSS AKCCTTIGRV MITYLDRVVD
710 720 730 740 750
GATLCAGVLR LAAEPRNPLL ASAPPRARDV DVSAALGHEL ELRFRSVYGD
760 770 780 790 800
TDSIFLELNL REVQTTLAVA RTLERVLNEH VLFENFRVEF EAIYQNLILQ
810 820 830 840 850
SKKKYSTTKY AADHRAGDAP EHVSKGTSET RRDVSRFHKL MISRYKAQLV
860 870 880 890 900
ALLAEARLSS RQVCIEMLRS LEVDLFAEFA ARAQPLEMFL LSRMHHRNYK
910 920 930 940 950
APDNPNVELV NRYNRENLEP IELGERYYYA YVCASELPWQ LAVANVRNHE
960 970 980 990 1000
RIVDASYVLP ERERVFYEIY FRRLATELVN LLDNKPLCAE FFTRLFGVRP

VFSN
Length:1,004
Mass (Da):115,103
Last modified:February 1, 1997 - v1
Checksum:i050EBD03FE967517
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U60315 Genomic DNA. Translation: AAC55167.1.
PIRiT30641.
RefSeqiNP_043990.1. NC_001731.1.

Genome annotation databases

GeneIDi1487060.
KEGGivg:1487060.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U60315 Genomic DNA. Translation: AAC55167.1.
PIRiT30641.
RefSeqiNP_043990.1. NC_001731.1.

3D structure databases

ProteinModelPortaliQ98207.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1487060.
KEGGivg:1487060.

Phylogenomic databases

KOiK18964.

Family and domain databases

Gene3Di3.30.420.10. 2 hits.
3.90.1600.10. 2 hits.
InterProiIPR006172. DNA-dir_DNA_pol_B.
IPR017964. DNA-dir_DNA_pol_B_CS.
IPR006133. DNA-dir_DNA_pol_B_exonuc.
IPR006134. DNA-dir_DNA_pol_B_multi_dom.
IPR013617. DNA-dir_DNA_pol_B_vir_insert.
IPR023211. DNA_pol_palm_dom.
IPR013660. DNApol_B_exo_N.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF00136. DNA_pol_B. 1 hit.
PF08408. DNA_pol_B_3. 1 hit.
PF03104. DNA_pol_B_exo1. 1 hit.
PF08452. DNAP_B_exo_N. 1 hit.
[Graphical view]
PRINTSiPR00106. DNAPOLB.
SMARTiSM00486. POLBc. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 2 hits.
PROSITEiPS00116. DNA_POLYMERASE_B. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ98207_MCV1
AccessioniPrimary (citable) accession number: Q98207
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: May 11, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.