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Protein

Signal recognition particle 19 kDa protein

Gene

srp19

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Signal recognition particle 19 kDa proteinUniRule annotation
Short name:
SRP19UniRule annotation
Gene namesi
Name:srp19UniRule annotation
Ordered Locus Names:SSO0165
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001974 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Signal recognition particle

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001352251 – 102Signal recognition particle 19 kDa proteinAdd BLAST102

Interactioni

Subunit structurei

Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.UniRule annotation

Protein-protein interaction databases

STRINGi273057.SSO0165.

Structurei

Secondary structure

1102
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi5 – 9Combined sources5
Beta strandi11 – 14Combined sources4
Helixi17 – 20Combined sources4
Turni24 – 27Combined sources4
Helixi39 – 48Combined sources10
Beta strandi54 – 56Combined sources3
Beta strandi70 – 74Combined sources5
Beta strandi76 – 78Combined sources3
Helixi79 – 90Combined sources12

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3KTWX-ray3.20A/B2-102[»]
ProteinModelPortaliQ980W2.
SMRiQ980W2.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ980W2.

Family & Domainsi

Sequence similaritiesi

Belongs to the SRP19 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01217. Archaea.
COG1400. LUCA.
HOGENOMiHOG000270389.
KOiK03105.
OMAiWLAYFIA.

Family and domain databases

Gene3Di3.30.56.30. 1 hit.
HAMAPiMF_00305. SRP19. 1 hit.
InterProiIPR002778. Signal_recog_particle_SRP19.
IPR022938. SRP19_arc-type.
[Graphical view]
PfamiPF01922. SRP19. 1 hit.
[Graphical view]
SUPFAMiSSF69695. SSF69695. 1 hit.

Sequencei

Sequence statusi: Complete.

Q980W2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLRDLKEEN RIVIWPSYFF SPTRSKGRRL ARIPYKIKTE ELVSTLRELG
60 70 80 90 100
LDPIVIENKK YPRDRKINFL IAVKKVKSKN YTLKIIHNAL MGTRQTNPNK

SN
Length:102
Mass (Da):12,029
Last modified:October 1, 2001 - v1
Checksum:i7AD3F7178B42AA40
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA. Translation: AAK40510.1.
PIRiG90156.
RefSeqiWP_009990389.1. NC_002754.1.

Genome annotation databases

EnsemblBacteriaiAAK40510; AAK40510; SSO0165.
GeneIDi27426455.
KEGGisso:SSO0165.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA. Translation: AAK40510.1.
PIRiG90156.
RefSeqiWP_009990389.1. NC_002754.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3KTWX-ray3.20A/B2-102[»]
ProteinModelPortaliQ980W2.
SMRiQ980W2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273057.SSO0165.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK40510; AAK40510; SSO0165.
GeneIDi27426455.
KEGGisso:SSO0165.

Phylogenomic databases

eggNOGiarCOG01217. Archaea.
COG1400. LUCA.
HOGENOMiHOG000270389.
KOiK03105.
OMAiWLAYFIA.

Miscellaneous databases

EvolutionaryTraceiQ980W2.

Family and domain databases

Gene3Di3.30.56.30. 1 hit.
HAMAPiMF_00305. SRP19. 1 hit.
InterProiIPR002778. Signal_recog_particle_SRP19.
IPR022938. SRP19_arc-type.
[Graphical view]
PfamiPF01922. SRP19. 1 hit.
[Graphical view]
SUPFAMiSSF69695. SSF69695. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSRP19_SULSO
AccessioniPrimary (citable) accession number: Q980W2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 20, 2002
Last sequence update: October 1, 2001
Last modified: November 30, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.