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Protein

Probable tRNA pseudouridine synthase D

Gene

truD

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei89NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:SSO0174
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001974 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001525541 – 377Probable tRNA pseudouridine synthase DAdd BLAST377

Proteomic databases

PRIDEiQ980V2

Interactioni

Protein-protein interaction databases

STRINGi273057.SSO0174

Structurei

3D structure databases

ProteinModelPortaliQ980V2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini160 – 377TRUDUniRule annotationAdd BLAST218

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04252 Archaea
COG0585 LUCA
HOGENOMiHOG000224849
InParanoidiQ980V2
KOiK06176
OMAiYPHPLDY
OrthoDBiPOG093Z087N

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 2 hits
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit

Sequencei

Sequence statusi: Complete.

Q980V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPHEIDIAL GMEKYYYEDW NELDGTIERP NGFKVIEEID FKPAQDWKGE
60 70 80 90 100
TKGKYAVFLL TKWGIDHFSA ISEVQKVLHS KVNYIGIKDA NAITSQLVYI
110 120 130 140 150
PLNEKQELIE KYQSRSFILK FLGFSSKKLN HTGNIFEISL SISDFDIVIE
160 170 180 190 200
RIEQIKKNPY LPAFIGYQRF GTRRPITHLI GKYLLRRDWE KAFYLILTYP
210 220 230 240 250
FLSESKETID IRKLIMEGDF KEAVRSIPSK FKQEKLLLKN YMRFNSYYLA
260 270 280 290 300
LKSSFIPISL YLDAYQSYLF NLYLSRKLDE YKNLNDKVNL LIRIPIYFNN
310 320 330 340 350
CDDVCKEIYL DEGIERNFFK LQEFKISLRD LVRKAFMNIR DLKVNEETKT
360 370
ISFVLERGMY ATILLREILR GDPRKFT
Length:377
Mass (Da):44,738
Last modified:October 1, 2001 - v1
Checksum:iD92C98109131D915
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA Translation: AAK40520.1
PIRiA90158
RefSeqiWP_009990399.1, NC_002754.1

Genome annotation databases

EnsemblBacteriaiAAK40520; AAK40520; SSO0174
GeneIDi27426465
KEGGisso:SSO0174
PATRICifig|273057.12.peg.170

Similar proteinsi

Entry informationi

Entry nameiTRUD_SULSO
AccessioniPrimary (citable) accession number: Q980V2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2003
Last sequence update: October 1, 2001
Last modified: May 23, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health