Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable tRNA pseudouridine synthase D

Gene

truD

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei89 – 891NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciSSOL273057:GCH2-163-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:SSO0174
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001974 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 377377Probable tRNA pseudouridine synthase DPRO_0000152554Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273057.SSO0174.

Structurei

3D structure databases

ProteinModelPortaliQ980V2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini160 – 377218TRUDUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation
Contains 1 TRUD domain.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04252. Archaea.
COG0585. LUCA.
HOGENOMiHOG000224849.
InParanoidiQ980V2.
KOiK06176.
OMAiRDWCKAV.

Family and domain databases

HAMAPiMF_01082. TruD. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERiPTHR13326. PTHR13326. 1 hit.
PfamiPF01142. TruD. 2 hits.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 2 hits.
PROSITEiPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q980V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPHEIDIAL GMEKYYYEDW NELDGTIERP NGFKVIEEID FKPAQDWKGE
60 70 80 90 100
TKGKYAVFLL TKWGIDHFSA ISEVQKVLHS KVNYIGIKDA NAITSQLVYI
110 120 130 140 150
PLNEKQELIE KYQSRSFILK FLGFSSKKLN HTGNIFEISL SISDFDIVIE
160 170 180 190 200
RIEQIKKNPY LPAFIGYQRF GTRRPITHLI GKYLLRRDWE KAFYLILTYP
210 220 230 240 250
FLSESKETID IRKLIMEGDF KEAVRSIPSK FKQEKLLLKN YMRFNSYYLA
260 270 280 290 300
LKSSFIPISL YLDAYQSYLF NLYLSRKLDE YKNLNDKVNL LIRIPIYFNN
310 320 330 340 350
CDDVCKEIYL DEGIERNFFK LQEFKISLRD LVRKAFMNIR DLKVNEETKT
360 370
ISFVLERGMY ATILLREILR GDPRKFT
Length:377
Mass (Da):44,738
Last modified:October 1, 2001 - v1
Checksum:iD92C98109131D915
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA. Translation: AAK40520.1.
PIRiA90158.
RefSeqiWP_009990399.1. NC_002754.1.

Genome annotation databases

EnsemblBacteriaiAAK40520; AAK40520; SSO0174.
GeneIDi27426465.
KEGGisso:SSO0174.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA. Translation: AAK40520.1.
PIRiA90158.
RefSeqiWP_009990399.1. NC_002754.1.

3D structure databases

ProteinModelPortaliQ980V2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273057.SSO0174.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK40520; AAK40520; SSO0174.
GeneIDi27426465.
KEGGisso:SSO0174.

Phylogenomic databases

eggNOGiarCOG04252. Archaea.
COG0585. LUCA.
HOGENOMiHOG000224849.
InParanoidiQ980V2.
KOiK06176.
OMAiRDWCKAV.

Enzyme and pathway databases

BioCyciSSOL273057:GCH2-163-MONOMER.

Family and domain databases

HAMAPiMF_01082. TruD. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERiPTHR13326. PTHR13326. 1 hit.
PfamiPF01142. TruD. 2 hits.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 2 hits.
PROSITEiPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTRUD_SULSO
AccessioniPrimary (citable) accession number: Q980V2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2003
Last sequence update: October 1, 2001
Last modified: July 6, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.