SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q980R2

- RPOA1_SULSO

UniProt

Q980R2 - RPOA1_SULSO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
DNA-directed RNA polymerase subunit A'
Gene
rpoA1, SSO0225
Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Cofactori

Zinc By similarity.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri58 – 10144C4-type Reviewed prediction
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. DNA-directed RNA polymerase activity Source: UniProtKB-KW
  3. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciSSOL273057:GCH2-213-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit A' (EC:2.7.7.6)
Gene namesi
Name:rpoA1
Ordered Locus Names:SSO0225
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000001974: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 880880DNA-directed RNA polymerase subunit A'
PRO_0000074008Add
BLAST

Interactioni

Protein-protein interaction databases

DIPiDIP-60638N.
STRINGi273057.SSO0225.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi16 – 216
Beta strandi47 – 493
Beta strandi58 – 614
Turni84 – 863
Helixi87 – 937
Beta strandi99 – 1024
Turni108 – 1125
Helixi114 – 1174
Helixi124 – 13815
Turni143 – 1453
Helixi177 – 1848
Helixi189 – 1968
Turni199 – 2013
Turni204 – 2063
Beta strandi207 – 2115
Helixi217 – 2193
Helixi234 – 25320
Beta strandi254 – 2563
Turni259 – 2613
Helixi262 – 27716
Beta strandi282 – 2843
Helixi298 – 3003
Helixi309 – 3124
Beta strandi314 – 3174
Beta strandi322 – 3287
Beta strandi330 – 3323
Beta strandi334 – 3396
Helixi343 – 3464
Beta strandi347 – 3504
Turni355 – 3573
Helixi358 – 36710
Turni368 – 3703
Beta strandi371 – 3733
Turni394 – 3963
Helixi397 – 4004
Beta strandi406 – 4105
Beta strandi416 – 4205
Helixi427 – 4293
Beta strandi430 – 4378
Beta strandi439 – 4457
Helixi447 – 4493
Helixi450 – 4534
Turni457 – 4593
Beta strandi461 – 4655
Helixi470 – 47910
Helixi483 – 4853
Turni489 – 4924
Beta strandi493 – 4964
Helixi501 – 5099
Helixi518 – 5236
Beta strandi541 – 5433
Helixi548 – 5525
Turni553 – 5553
Beta strandi562 – 5643
Helixi571 – 5733
Beta strandi581 – 5833
Beta strandi585 – 5917
Helixi600 – 6034
Turni607 – 6093
Helixi611 – 6177
Helixi623 – 6308
Helixi632 – 6398
Turni640 – 6423
Turni649 – 6513
Helixi657 – 6626
Helixi665 – 68016
Helixi692 – 71524
Turni716 – 7183
Helixi724 – 7285
Beta strandi729 – 7346
Helixi737 – 7448
Beta strandi760 – 7634
Beta strandi778 – 7803
Turni786 – 7883
Helixi794 – 81118
Helixi813 – 82412
Beta strandi841 – 8433
Beta strandi845 – 8495
Helixi850 – 8523
Helixi857 – 8593
Beta strandi860 – 8645
Helixi867 – 8748
Turni875 – 8773

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2PMZX-ray3.40A/Q1-880[»]
3HKZX-ray3.40A/I1-880[»]
ProteinModelPortaliQ980R2.
SMRiQ980R2. Positions 4-879.

Miscellaneous databases

EvolutionaryTraceiQ980R2.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiCOG0086.
HOGENOMiHOG000222974.
KOiK03041.
OMAiYFFHAMG.

Family and domain databases

InterProiIPR000722. RNA_pol_asu.
IPR006592. RNA_pol_N.
IPR007080. RNA_pol_Rpb1_1.
IPR007066. RNA_pol_Rpb1_3.
IPR007083. RNA_pol_Rpb1_4.
IPR007081. RNA_pol_Rpb1_5.
IPR012758. RNAP_A1.
[Graphical view]
PfamiPF04997. RNA_pol_Rpb1_1. 1 hit.
PF00623. RNA_pol_Rpb1_2. 1 hit.
PF04983. RNA_pol_Rpb1_3. 1 hit.
PF05000. RNA_pol_Rpb1_4. 1 hit.
PF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
SMARTiSM00663. RPOLA_N. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02390. RNA_pol_rpoA1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q980R2-1 [UniParc]FASTAAdd to Basket

« Hide

MSEKNIKGIK FGILSPDEIR KMSVTAIITP DVYDEDGTPI EGSVMDPRLG    50
VIEPGQKCPT CGNTLGNCPG HFGHIELVRP VIHVGLVKHI YEFLKATCRR 100
CGRVKISEDE IEKYSRIYNA IKKRWPSAAR RLTEYVKKTA MKAQVCPHCN 150
EKQYKIKLEK PYNFYEERKE GVAKLTPSDI RERLEKIPDS DVEILGYDPT 200
TSRPEWMILT VLPVPPITIR PSIMIESGIR AEDDLTHKLV DIVRINERLK 250
ESIDAGAPQL IIEDLWDLLQ YHVATYFDNE IPGLPPSKHR SGRPLRTLAQ 300
RLKGKEGRFR GNLSGKRVDF SSRTVISPDP NISIDEVGVP EIIAKTLTVP 350
ERITPWNIEK LRQFVINGPD KWPGANYVIR PDGRRIDLRY VKDRKELAST 400
LAPGYIIERH LIDGDIVLFN RQPSLHRISM MAHRVRVLKG LTFRLNLLVC 450
PPYNADFDGD EMNLHVPQSE EAIAEAKEIM LVHKNIITPR YGGPIIGAAQ 500
DYISGAYLLT VKTTLLTKEE AQQILGVADV KIDLGEPAIL APREYYTGKQ 550
VISAFLPKDF NFHGQANVSS GPRLCKNEDC PHDSYVVIKN GILLEGVFDK 600
KAIGNQQPES ILHWLIKEYS DEYGKWLMDN LFRVFIRFVE LQGFTMRLED 650
VSLGDDVKKE IYNEIDRAKV EVDNLIQKYK NGELEPIPGR TLEESLENYI 700
LDTLDKLRST AGDIASKYLD PFNFAYVMAR TGARGSVLNI TQMAAMLGQQ 750
SVRGERIKRG YMTRTLPHFK PYDISPEARG FIYSSFRTGL KPTELFFHAA 800
GGREGLVDTA VRTSQSGYMQ RRLINALSDL RAEYDGTVRS LYGEVVQVAY 850
GDDGVFPMYS AHGKTVDVNR IFERVVGWKA 880
Length:880
Mass (Da):99,675
Last modified:October 1, 2001 - v1
Checksum:i5C8AE20EFC71DE25
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006641 Genomic DNA. Translation: AAK40566.1.
PIRiG90163.
RefSeqiNP_341776.1. NC_002754.1.

Genome annotation databases

EnsemblBacteriaiAAK40566; AAK40566; SSO0225.
GeneIDi1455376.
KEGGisso:SSO0225.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006641 Genomic DNA. Translation: AAK40566.1 .
PIRi G90163.
RefSeqi NP_341776.1. NC_002754.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2PMZ X-ray 3.40 A/Q 1-880 [» ]
3HKZ X-ray 3.40 A/I 1-880 [» ]
ProteinModelPortali Q980R2.
SMRi Q980R2. Positions 4-879.
ModBasei Search...

Protein-protein interaction databases

DIPi DIP-60638N.
STRINGi 273057.SSO0225.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK40566 ; AAK40566 ; SSO0225 .
GeneIDi 1455376.
KEGGi sso:SSO0225.

Phylogenomic databases

eggNOGi COG0086.
HOGENOMi HOG000222974.
KOi K03041.
OMAi YFFHAMG.

Enzyme and pathway databases

BioCyci SSOL273057:GCH2-213-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q980R2.

Family and domain databases

InterProi IPR000722. RNA_pol_asu.
IPR006592. RNA_pol_N.
IPR007080. RNA_pol_Rpb1_1.
IPR007066. RNA_pol_Rpb1_3.
IPR007083. RNA_pol_Rpb1_4.
IPR007081. RNA_pol_Rpb1_5.
IPR012758. RNAP_A1.
[Graphical view ]
Pfami PF04997. RNA_pol_Rpb1_1. 1 hit.
PF00623. RNA_pol_Rpb1_2. 1 hit.
PF04983. RNA_pol_Rpb1_3. 1 hit.
PF05000. RNA_pol_Rpb1_4. 1 hit.
PF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view ]
SMARTi SM00663. RPOLA_N. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02390. RNA_pol_rpoA1. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.
  2. "The X-ray crystal structure of RNA polymerase from Archaea."
    Hirata A., Klein B.J., Murakami K.S.
    Nature 451:851-854(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.4 ANGSTROMS) OF THE RNA POLYMERASE COMPLEX.

Entry informationi

Entry nameiRPOA1_SULSO
AccessioniPrimary (citable) accession number: Q980R2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: October 1, 2001
Last modified: May 14, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi