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Q980R2 (RPOA1_SULSO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit A'
EC=2.7.7.6
Gene names
Name:rpoA1
Ordered Locus Names:SSO0225
OrganismSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifier273057 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length880 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Cofactor

Zinc By similarity.

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Ontologies

Keywords
   Biological processTranscription
   Cellular componentDNA-directed RNA polymerase
   DomainZinc-finger
   LigandMetal-binding
Zinc
   Molecular functionNucleotidyltransferase
Transferase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Molecular functionDNA binding

Inferred from electronic annotation. Source: InterPro

DNA-directed RNA polymerase activity

Inferred from electronic annotation. Source: UniProtKB-KW

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 880880DNA-directed RNA polymerase subunit A'
PRO_0000074008

Regions

Zinc finger58 – 10144C4-type Potential

Secondary structure

1 ................................................................................................................................... 880
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q980R2 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: 5C8AE20EFC71DE25

FASTA88099,675
        10         20         30         40         50         60 
MSEKNIKGIK FGILSPDEIR KMSVTAIITP DVYDEDGTPI EGSVMDPRLG VIEPGQKCPT 

        70         80         90        100        110        120 
CGNTLGNCPG HFGHIELVRP VIHVGLVKHI YEFLKATCRR CGRVKISEDE IEKYSRIYNA 

       130        140        150        160        170        180 
IKKRWPSAAR RLTEYVKKTA MKAQVCPHCN EKQYKIKLEK PYNFYEERKE GVAKLTPSDI 

       190        200        210        220        230        240 
RERLEKIPDS DVEILGYDPT TSRPEWMILT VLPVPPITIR PSIMIESGIR AEDDLTHKLV 

       250        260        270        280        290        300 
DIVRINERLK ESIDAGAPQL IIEDLWDLLQ YHVATYFDNE IPGLPPSKHR SGRPLRTLAQ 

       310        320        330        340        350        360 
RLKGKEGRFR GNLSGKRVDF SSRTVISPDP NISIDEVGVP EIIAKTLTVP ERITPWNIEK 

       370        380        390        400        410        420 
LRQFVINGPD KWPGANYVIR PDGRRIDLRY VKDRKELAST LAPGYIIERH LIDGDIVLFN 

       430        440        450        460        470        480 
RQPSLHRISM MAHRVRVLKG LTFRLNLLVC PPYNADFDGD EMNLHVPQSE EAIAEAKEIM 

       490        500        510        520        530        540 
LVHKNIITPR YGGPIIGAAQ DYISGAYLLT VKTTLLTKEE AQQILGVADV KIDLGEPAIL 

       550        560        570        580        590        600 
APREYYTGKQ VISAFLPKDF NFHGQANVSS GPRLCKNEDC PHDSYVVIKN GILLEGVFDK 

       610        620        630        640        650        660 
KAIGNQQPES ILHWLIKEYS DEYGKWLMDN LFRVFIRFVE LQGFTMRLED VSLGDDVKKE 

       670        680        690        700        710        720 
IYNEIDRAKV EVDNLIQKYK NGELEPIPGR TLEESLENYI LDTLDKLRST AGDIASKYLD 

       730        740        750        760        770        780 
PFNFAYVMAR TGARGSVLNI TQMAAMLGQQ SVRGERIKRG YMTRTLPHFK PYDISPEARG 

       790        800        810        820        830        840 
FIYSSFRTGL KPTELFFHAA GGREGLVDTA VRTSQSGYMQ RRLINALSDL RAEYDGTVRS 

       850        860        870        880 
LYGEVVQVAY GDDGVFPMYS AHGKTVDVNR IFERVVGWKA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE006641 Genomic DNA. Translation: AAK40566.1.
PIRG90163.
RefSeqNP_341776.1. NC_002754.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2PMZX-ray3.40A/Q1-880[»]
3HKZX-ray3.40A/I1-880[»]
ProteinModelPortalQ980R2.
SMRQ980R2. Positions 4-879.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1455376.
GenomeReviewsGene locus SSO0225 in contig AE006641_GR.
KEGGsso:SSO0225.
NMPDRfig|273057.1.peg.199.

Phylogenomic databases

HOGENOMHBG499785.
OMAHKLVDII.
ProtClustDBPRK08566.

Enzyme and pathway databases

BioCycSSOL273057:SSO0225-MONOMER.

Family and domain databases

InterProIPR012758. DNA-dir_RpoA1.
IPR000722. RNA_pol_asu.
IPR006592. RNA_pol_N.
IPR007080. RNA_pol_Rpb1_1.
IPR007066. RNA_pol_Rpb1_3.
IPR007083. RNA_pol_Rpb1_4.
IPR007081. RNA_pol_Rpb1_5.
[Graphical view]
KOK03041.
PfamPF04997. RNA_pol_Rpb1_1. 1 hit.
PF00623. RNA_pol_Rpb1_2. 1 hit.
PF04983. RNA_pol_Rpb1_3. 1 hit.
PF05000. RNA_pol_Rpb1_4. 1 hit.
PF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
SMARTSM00663. RPOLA_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR02390. RNA_pol_rpoA1. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRPOA1_SULSO
AccessionPrimary (citable) accession number: Q980R2
Entry history
Integrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: October 1, 2001
Last modified: December 14, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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