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Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB1

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi586ZincCombined sources1
Metal bindingi589ZincCombined sources1
Metal bindingi604ZincCombined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferaseUniRule annotationImported, Transferase
Biological processTranscription
LigandMetal-bindingCombined sources, ZincCombined sources

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Gene namesi
Name:rpoB1Imported
Ordered Locus Names:SSO0227Imported
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)Imported
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001974 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

DNA-directed RNA polymeraseUniRule annotationImported

Interactioni

Protein-protein interaction databases

DIPiDIP-60640N.
STRINGi273057.SSO0227.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PMZX-ray3.40B/R4-649[»]
3HKZX-ray3.40B/J4-649[»]
ProteinModelPortaliQ980R1.
SMRiQ980R1.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ980R1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 107RNA_pol_Rpb2_4InterPro annotationAdd BLAST63
Domaini129 – 163RNA_pol_Rpb2_5InterPro annotationAdd BLAST35
Domaini177 – 547RNA_pol_Rpb2_6InterPro annotationAdd BLAST371
Domaini549 – 640RNA_pol_Rpb2_7InterPro annotationAdd BLAST92

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01762. Archaea.
COG0085. LUCA.
HOGENOMiHOG000222962.
InParanoidiQ980R1.
KOiK03044.
OMAiQKLYHMV.
OrthoDBiPOG093Z00X6.

Family and domain databases

CDDicd00653. RNA_pol_B_RPB2. 1 hit.
Gene3Di2.40.270.10. 2 hits.
InterProiView protein in InterPro
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007646. RNA_pol_Rpb2_4.
IPR007647. RNA_pol_Rpb2_5.
IPR007641. RNA_pol_Rpb2_7.
IPR019969. RNAP_B.
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiView protein in Pfam
PF04566. RNA_pol_Rpb2_4. 1 hit.
PF04567. RNA_pol_Rpb2_5. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
TIGRFAMsiTIGR03670. rpoB_arch. 1 hit.
PROSITEiView protein in PROSITE
PS01166. RNA_POL_BETA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q980R1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYGINERIV EKTLYEMGVV PVEEVIRRVT EGGEDQNEYL KWSKVILNGR
60 70 80 90 100
LIGYYQDGGE LANKIRERRR KGEISDEVNV GHIVTDFINE VHVNCDSGRV
110 120 130 140 150
RRPLIIVSNG NPLVTIEDIE KLESGAITFD DLVRQGKIEY LDAEEEENAY
160 170 180 190 200
VALEPNDLTP DHTHLEIWSP AILGITASII PYPEHNQSPR NTYQSAMAKQ
210 220 230 240 250
ALGLYAANYQ LRTDTRAHLL HYPQRPLVQT RALDIIGYTN RPAGNNAILA
260 270 280 290 300
VMSFTGYNME DSIIMNRSSV ERGMYRSTFF RLYSTEEVKY PGGQEDKIVM
310 320 330 340 350
PEAGVRGYKG KEYYRLLEDN GVVSPEVEVK GGDVLIGKVS PPRFLQEFKE
360 370 380 390 400
LSPEQAKRDT SIVTRHGEMG IVDLVLITET AEGNKLVKVR VRDLRIPTIG
410 420 430 440 450
DKFASRHGQK GVIGMLIPQV DMPYTVKGVV PDIILNPHAL PSRMTLGQIM
460 470 480 490 500
EGIAGKYAAL SGNIVDATPF YKTPIEQLQN EILRYGYLPD ATEVVYDGRT
510 520 530 540 550
GQKIKSRIYF GVVYYQKLHH MVADKLHARA RGPVQILTRQ PTEGRAREGG
560 570 580 590 600
LRFGEMERDC LIGFGTAMLL KDRLLDNSDR TMIYVCDQCG YIGWYDKNKN
610 620 630 640
KYVCPIHGDK SNLFPVTVSY AFKLLIQELM SMIISPRLVL EDKVGLSGG
Length:649
Mass (Da):73,124
Last modified:October 1, 2001 - v1
Checksum:i5221C683EA213126
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA. Translation: AAK40567.1.
PIRiH90163.

Genome annotation databases

EnsemblBacteriaiAAK40567; AAK40567; SSO0227.
KEGGisso:SSO0227.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA. Translation: AAK40567.1.
PIRiH90163.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PMZX-ray3.40B/R4-649[»]
3HKZX-ray3.40B/J4-649[»]
ProteinModelPortaliQ980R1.
SMRiQ980R1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60640N.
STRINGi273057.SSO0227.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK40567; AAK40567; SSO0227.
KEGGisso:SSO0227.

Phylogenomic databases

eggNOGiarCOG01762. Archaea.
COG0085. LUCA.
HOGENOMiHOG000222962.
InParanoidiQ980R1.
KOiK03044.
OMAiQKLYHMV.
OrthoDBiPOG093Z00X6.

Miscellaneous databases

EvolutionaryTraceiQ980R1.

Family and domain databases

CDDicd00653. RNA_pol_B_RPB2. 1 hit.
Gene3Di2.40.270.10. 2 hits.
InterProiView protein in InterPro
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007646. RNA_pol_Rpb2_4.
IPR007647. RNA_pol_Rpb2_5.
IPR007641. RNA_pol_Rpb2_7.
IPR019969. RNAP_B.
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiView protein in Pfam
PF04566. RNA_pol_Rpb2_4. 1 hit.
PF04567. RNA_pol_Rpb2_5. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
TIGRFAMsiTIGR03670. rpoB_arch. 1 hit.
PROSITEiView protein in PROSITE
PS01166. RNA_POL_BETA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ980R1_SULSO
AccessioniPrimary (citable) accession number: Q980R1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2001
Last sequence update: October 1, 2001
Last modified: April 12, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.