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Q980R1

- Q980R1_SULSO

UniProt

Q980R1 - Q980R1_SULSO

Protein

DNA-directed RNA polymerase

Gene

rpoB1

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (01 Oct 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi586 – 5861ZincImported
    Metal bindingi589 – 5891ZincImported
    Metal bindingi604 – 6041ZincImported

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. DNA-directed RNA polymerase activity Source: UniProtKB-KW
    3. ribonucleoside binding Source: InterPro
    4. zinc ion binding Source: InterPro

    GO - Biological processi

    1. transcription, DNA-templated Source: InterPro

    Keywords - Molecular functioni

    NucleotidyltransferaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    Transcription

    Keywords - Ligandi

    Metal-bindingImported, ZincImported

    Enzyme and pathway databases

    BioCyciSSOL273057:GCH2-214-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA-directed RNA polymeraseUniRule annotation (EC:2.7.7.6UniRule annotation)
    Gene namesi
    Name:rpoB1Imported
    Ordered Locus Names:SSO0227Imported
    OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)Imported
    Taxonomic identifieri273057 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
    ProteomesiUP000001974: Chromosome

    Subcellular locationi

    Keywords - Cellular componenti

    DNA-directed RNA polymeraseUniRule annotationImported

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-60640N.
    STRINGi273057.SSO0227.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2PMZX-ray3.40B/R4-649[»]
    3HKZX-ray3.40B/J4-649[»]
    ProteinModelPortaliQ980R1.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ980R1.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RNA polymerase beta chain family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0085.
    HOGENOMiHOG000222962.
    KOiK03044.
    OMAiQKLYHMV.

    Family and domain databases

    Gene3Di2.40.270.10. 2 hits.
    2.40.50.150. 1 hit.
    InterProiIPR015712. DNA-dir_RNA_pol_su2.
    IPR007120. DNA-dir_RNA_pol_su2_6.
    IPR007121. RNA_pol_bsu_CS.
    IPR007646. RNA_pol_Rpb2_4.
    IPR007647. RNA_pol_Rpb2_5.
    IPR007641. RNA_pol_Rpb2_7.
    IPR014724. RNA_pol_RPB2_OB-fold.
    IPR019969. RNAP_B.
    [Graphical view]
    PANTHERiPTHR20856. PTHR20856. 1 hit.
    PfamiPF04566. RNA_pol_Rpb2_4. 1 hit.
    PF04567. RNA_pol_Rpb2_5. 1 hit.
    PF00562. RNA_pol_Rpb2_6. 1 hit.
    PF04560. RNA_pol_Rpb2_7. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR03670. rpoB_arch. 1 hit.
    PROSITEiPS01166. RNA_POL_BETA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q980R1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLYGINERIV EKTLYEMGVV PVEEVIRRVT EGGEDQNEYL KWSKVILNGR    50
    LIGYYQDGGE LANKIRERRR KGEISDEVNV GHIVTDFINE VHVNCDSGRV 100
    RRPLIIVSNG NPLVTIEDIE KLESGAITFD DLVRQGKIEY LDAEEEENAY 150
    VALEPNDLTP DHTHLEIWSP AILGITASII PYPEHNQSPR NTYQSAMAKQ 200
    ALGLYAANYQ LRTDTRAHLL HYPQRPLVQT RALDIIGYTN RPAGNNAILA 250
    VMSFTGYNME DSIIMNRSSV ERGMYRSTFF RLYSTEEVKY PGGQEDKIVM 300
    PEAGVRGYKG KEYYRLLEDN GVVSPEVEVK GGDVLIGKVS PPRFLQEFKE 350
    LSPEQAKRDT SIVTRHGEMG IVDLVLITET AEGNKLVKVR VRDLRIPTIG 400
    DKFASRHGQK GVIGMLIPQV DMPYTVKGVV PDIILNPHAL PSRMTLGQIM 450
    EGIAGKYAAL SGNIVDATPF YKTPIEQLQN EILRYGYLPD ATEVVYDGRT 500
    GQKIKSRIYF GVVYYQKLHH MVADKLHARA RGPVQILTRQ PTEGRAREGG 550
    LRFGEMERDC LIGFGTAMLL KDRLLDNSDR TMIYVCDQCG YIGWYDKNKN 600
    KYVCPIHGDK SNLFPVTVSY AFKLLIQELM SMIISPRLVL EDKVGLSGG 649
    Length:649
    Mass (Da):73,124
    Last modified:October 1, 2001 - v1
    Checksum:i5221C683EA213126
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006641 Genomic DNA. Translation: AAK40567.1.
    PIRiH90163.
    RefSeqiNP_341777.1. NC_002754.1.

    Genome annotation databases

    EnsemblBacteriaiAAK40567; AAK40567; SSO0227.
    GeneIDi1455377.
    KEGGisso:SSO0227.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006641 Genomic DNA. Translation: AAK40567.1 .
    PIRi H90163.
    RefSeqi NP_341777.1. NC_002754.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2PMZ X-ray 3.40 B/R 4-649 [» ]
    3HKZ X-ray 3.40 B/J 4-649 [» ]
    ProteinModelPortali Q980R1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-60640N.
    STRINGi 273057.SSO0227.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK40567 ; AAK40567 ; SSO0227 .
    GeneIDi 1455377.
    KEGGi sso:SSO0227.

    Phylogenomic databases

    eggNOGi COG0085.
    HOGENOMi HOG000222962.
    KOi K03044.
    OMAi QKLYHMV.

    Enzyme and pathway databases

    BioCyci SSOL273057:GCH2-214-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q980R1.

    Family and domain databases

    Gene3Di 2.40.270.10. 2 hits.
    2.40.50.150. 1 hit.
    InterProi IPR015712. DNA-dir_RNA_pol_su2.
    IPR007120. DNA-dir_RNA_pol_su2_6.
    IPR007121. RNA_pol_bsu_CS.
    IPR007646. RNA_pol_Rpb2_4.
    IPR007647. RNA_pol_Rpb2_5.
    IPR007641. RNA_pol_Rpb2_7.
    IPR014724. RNA_pol_RPB2_OB-fold.
    IPR019969. RNAP_B.
    [Graphical view ]
    PANTHERi PTHR20856. PTHR20856. 1 hit.
    Pfami PF04566. RNA_pol_Rpb2_4. 1 hit.
    PF04567. RNA_pol_Rpb2_5. 1 hit.
    PF00562. RNA_pol_Rpb2_6. 1 hit.
    PF04560. RNA_pol_Rpb2_7. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR03670. rpoB_arch. 1 hit.
    PROSITEi PS01166. RNA_POL_BETA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2Imported.
    2. "The X-ray crystal structure of RNA polymerase from Archaea."
      Hirata A., Klein B.J., Murakami K.S.
      Nature 451:851-854(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.40 ANGSTROMS) OF 4-649 IN COMPLEX WITH ZINC.

    Entry informationi

    Entry nameiQ980R1_SULSO
    AccessioniPrimary (citable) accession number: Q980R1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2001
    Last sequence update: October 1, 2001
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3