Q980Q9 (RPOH_SULSO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit H
EC=2.7.7.6

Gene names

Name:	rpoH
Ordered Locus Names:	SSO5468

Organism

Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

Taxonomic identifier

273057 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	84 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. HAMAP MF_00025
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP MF_00025
Sequence similarities	Belongs to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 84

84

DNA-directed RNA polymerase subunit H HAMAP MF_00025

PRO_0000146104

Secondary structure

1

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84

Helix Strand Turn

Details...

Beta strand

14 – 16

3

Turn

25 – 27

3

Helix

28 – 34

7

Beta strand

41 – 43

3

Turn

50 – 56

7

Beta strand

63 – 67

5

Beta strand

70 – 73

4

Beta strand

75 – 78

4

Sequences

	Sequence		Length	Mass (Da)
	Q980Q9 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 2873A2053F864712	FASTA	84	9,670
	10 20 30 40 50 60 MRGSSNKKID PRIHYLVPKH EVLNIDEAYK ILKELGIRPE QLPWIRASDP VARSINAKPG 70 80 DIIRIIRKSQ LYGEVVSYRY VISG

References

[1]

"The complete genome of the crenarchaeon Sulfolobus solfataricus P2." She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J., Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G., Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J., Medina N., Peng X. , Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C., Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T., Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J. Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001) [PubMed: 11427726] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.

+

Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE006641 Genomic DNA. Translation: AAK40569.1.

PIR

B90164.

RefSeq

NP_341779.1. NC_002754.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2PMZ	X-ray	3.40	H/V	1-84	[»]
3HKZ	X-ray	3.40	H/T	1-84	[»]

ProteinModelPortal

Q980Q9.

SMR

Q980Q9. Positions 9-82.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1455379.

GenomeReviews

Gene locus SSO5468 in contig AE006641_GR.

KEGG

sso:SSO5468.

NMPDR

fig|273057.1.peg.202.

Phylogenomic databases

HOGENOM

HBG496846.

OMA

EHELVPK.

ProtClustDB

PRK09570.

Enzyme and pathway databases

BioCyc

SSOL273057:SSO5468-MONOMER.

Family and domain databases

HAMAP

MF_00025. RNApol_arch_H.
[Tree]

InterPro

IPR020609. DNA-dir_RNA_pol_subH/Rpb5_arc.
IPR000783. RNA_pol_subH/Rpb5_C.
IPR020608. RNA_pol_subH/Rpb5_CS.
[Graphical view]

Gene3D

G3DSA:3.90.940.20. RNApol_RPB5. 1 hit.

KO

K03053.

Pfam

PF01191. RNA_pol_Rpb5_C. 1 hit.
[Graphical view]

ProDom

PD005155. RNA_pol_subH/Rpb5_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]

SUPFAM

SSF55287. RNApol_RPB5_like. 1 hit.

PROSITE

PS01110. RNA_POL_H_23KD. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

RPOH_SULSO

Accession

Primary (citable) accession number: Q980Q9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 3, 2002
Last sequence update:	October 1, 2001
Last modified:	November 16, 2011
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program