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Protein

DNA-directed RNA polymerase subunit H

Gene

rpoH

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit HUniRule annotation (EC:2.7.7.6UniRule annotation)
Gene namesi
Name:rpoHUniRule annotation
Ordered Locus Names:SSO5468
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001974 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001461041 – 84DNA-directed RNA polymerase subunit HAdd BLAST84

Interactioni

Protein-protein interaction databases

DIPiDIP-60641N.
STRINGi273057.SSO5468.

Structurei

Secondary structure

184
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi14 – 16Combined sources3
Turni25 – 27Combined sources3
Helixi28 – 34Combined sources7
Beta strandi41 – 43Combined sources3
Turni50 – 56Combined sources7
Beta strandi59 – 61Combined sources3
Beta strandi63 – 67Combined sources5
Beta strandi70 – 73Combined sources4
Beta strandi75 – 78Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PMZX-ray3.40H/V1-84[»]
3HKZX-ray3.40H/T1-84[»]
ProteinModelPortaliQ980Q9.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ980Q9.

Family & Domainsi

Sequence similaritiesi

Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04258. Archaea.
COG2012. LUCA.
HOGENOMiHOG000109413.
InParanoidiQ980Q9.
KOiK03053.
OMAiDHILVPK.

Family and domain databases

Gene3Di3.90.940.20. 1 hit.
HAMAPiMF_00025. RNApol_RpoH_RPB5. 1 hit.
InterProiIPR000783. RNA_pol_subH/Rpb5_C.
IPR020608. RNA_pol_subH/Rpb5_CS.
IPR020609. RpoH/RPB5.
[Graphical view]
PfamiPF01191. RNA_pol_Rpb5_C. 1 hit.
[Graphical view]
ProDomiPD005155. RNA_pol_subH/Rpb5_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF55287. SSF55287. 1 hit.
PROSITEiPS01110. RNA_POL_H_23KD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q980Q9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGSSNKKID PRIHYLVPKH EVLNIDEAYK ILKELGIRPE QLPWIRASDP
60 70 80
VARSINAKPG DIIRIIRKSQ LYGEVVSYRY VISG
Length:84
Mass (Da):9,670
Last modified:October 1, 2001 - v1
Checksum:i2873A2053F864712
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA. Translation: AAK40569.1.
PIRiB90164.
RefSeqiWP_009990480.1. NC_002754.1.

Genome annotation databases

EnsemblBacteriaiAAK40569; AAK40569; SSO5468.
GeneIDi27426522.
KEGGisso:SSO5468.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA. Translation: AAK40569.1.
PIRiB90164.
RefSeqiWP_009990480.1. NC_002754.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PMZX-ray3.40H/V1-84[»]
3HKZX-ray3.40H/T1-84[»]
ProteinModelPortaliQ980Q9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60641N.
STRINGi273057.SSO5468.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK40569; AAK40569; SSO5468.
GeneIDi27426522.
KEGGisso:SSO5468.

Phylogenomic databases

eggNOGiarCOG04258. Archaea.
COG2012. LUCA.
HOGENOMiHOG000109413.
InParanoidiQ980Q9.
KOiK03053.
OMAiDHILVPK.

Miscellaneous databases

EvolutionaryTraceiQ980Q9.

Family and domain databases

Gene3Di3.90.940.20. 1 hit.
HAMAPiMF_00025. RNApol_RpoH_RPB5. 1 hit.
InterProiIPR000783. RNA_pol_subH/Rpb5_C.
IPR020608. RNA_pol_subH/Rpb5_CS.
IPR020609. RpoH/RPB5.
[Graphical view]
PfamiPF01191. RNA_pol_Rpb5_C. 1 hit.
[Graphical view]
ProDomiPD005155. RNA_pol_subH/Rpb5_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF55287. SSF55287. 1 hit.
PROSITEiPS01110. RNA_POL_H_23KD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRPOH_SULSO
AccessioniPrimary (citable) accession number: Q980Q9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2002
Last sequence update: October 1, 2001
Last modified: November 2, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.