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Q97ZX0

- SYW_SULSO

UniProt

Q97ZX0 - SYW_SULSO

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Protein

Tryptophan--tRNA ligase

Gene

trpS

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. tryptophan-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. tryptophanyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSSOL273057:GCH2-437-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Tryptophan--tRNA ligaseUniRule annotation (EC:6.1.1.2UniRule annotation)
Alternative name(s):
Tryptophanyl-tRNA synthetaseUniRule annotation
Short name:
TrpRSUniRule annotation
Gene namesi
Name:trpSUniRule annotation
Ordered Locus Names:SSO0452
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000001974: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 380380Tryptophan--tRNA ligasePRO_0000136733Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273057.SSO0452.

Structurei

3D structure databases

ProteinModelPortaliQ97ZX0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi81 – 899"HIGH" region
Motifi253 – 2575"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0180.
HOGENOMiHOG000224742.
InParanoidiQ97ZX0.
KOiK01867.
OMAiEFVVTPW.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_00140_A. Trp_tRNA_synth_A.
InterProiIPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR020653. Tryptophan-tRNA-ligase_arc.
[Graphical view]
PANTHERiPTHR10055. PTHR10055. 1 hit.
PfamiPF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PRINTSiPR01039. TRNASYNTHTRP.
TIGRFAMsiTIGR00233. trpS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q97ZX0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPDEFTVTPW EVKGKVDYDK LIVQFGTQKI TEELKQRIKN LAGDLHVMLR
60 70 80 90 100
RNVFFSHRDL DLVLNDYEKS KGFFLYTGRA PSLGMHIGHL IPFIFTKWLQ
110 120 130 140 150
EKFNANLYIE ITDDEKYMRN PEFTLDQTRS WAYDNILDII AVGFNPDKTF
160 170 180 190 200
IFQDTEYIRN MYPITVKIAK KLTFSEVRAT FGLDASSNIG LIFYPALQIA
210 220 230 240 250
PTMFEKKRCL IPAGIDQDPY WRLQRDIAES LGYYKAAQIH SKFLPPLTGP
260 270 280 290 300
EGKMSSSNPE TAIYLVDDPK TVERKIMKYA FSGGQPTIEL HRKYGGNPEI
310 320 330 340 350
DVPFQWLYYF FEEDDNRIKE IEEEYRSGKM LTGELKQILI DKLNNFLEEH
360 370 380
RRRREEAKEL VHVFKYDGKL AKQMWEKIHE
Length:380
Mass (Da):44,691
Last modified:April 16, 2002 - v2
Checksum:iCF8344CF63883680
GO

Sequence cautioni

The sequence AAK40778.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006641 Genomic DNA. Translation: AAK40778.1. Different initiation.
PIRiC90190.
RefSeqiNP_341988.2. NC_002754.1.

Genome annotation databases

EnsemblBacteriaiAAK40778; AAK40778; SSO0452.
GeneIDi1455588.
KEGGisso:SSO0452.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006641 Genomic DNA. Translation: AAK40778.1 . Different initiation.
PIRi C90190.
RefSeqi NP_341988.2. NC_002754.1.

3D structure databases

ProteinModelPortali Q97ZX0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273057.SSO0452.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK40778 ; AAK40778 ; SSO0452 .
GeneIDi 1455588.
KEGGi sso:SSO0452.

Phylogenomic databases

eggNOGi COG0180.
HOGENOMi HOG000224742.
InParanoidi Q97ZX0.
KOi K01867.
OMAi EFVVTPW.

Enzyme and pathway databases

BioCyci SSOL273057:GCH2-437-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
HAMAPi MF_00140_A. Trp_tRNA_synth_A.
InterProi IPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR020653. Tryptophan-tRNA-ligase_arc.
[Graphical view ]
PANTHERi PTHR10055. PTHR10055. 1 hit.
Pfami PF00579. tRNA-synt_1b. 1 hit.
[Graphical view ]
PRINTSi PR01039. TRNASYNTHTRP.
TIGRFAMsi TIGR00233. trpS. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.

Entry informationi

Entry nameiSYW_SULSO
AccessioniPrimary (citable) accession number: Q97ZX0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: April 16, 2002
Last modified: October 29, 2014
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3