ID   Q97ZH3_SACS2            Unreviewed;       412 AA.
AC   Q97ZH3;
DT   01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2001, sequence version 1.
DT   27-MAR-2024, entry version 109.
DE   SubName: Full=Pre mRNA splicing protein {ECO:0000313|EMBL:AAK41215.1};
GN   OrderedLocusNames=SSO0939 {ECO:0000313|EMBL:AAK41215.1};
OS   Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
OS   (Sulfolobus solfataricus).
OC   Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Saccharolobus.
OX   NCBI_TaxID=273057 {ECO:0000313|EMBL:AAK41215.1, ECO:0000313|Proteomes:UP000001974};
RN   [1] {ECO:0000313|Proteomes:UP000001974}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2
RC   {ECO:0000313|Proteomes:UP000001974};
RX   PubMed=11427726; DOI=10.1073/pnas.141222098;
RA   She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J.,
RA   Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G.,
RA   Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J.,
RA   Medina N., Peng X., Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C.,
RA   Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T.,
RA   Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J.;
RT   "The complete genome of the crenarchaeon Sulfolobus solfataricus P2.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001).
RN   [2] {ECO:0007829|PDB:3ICX, ECO:0007829|PDB:3ID5}
RP   X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 1-262.
RX   PubMed=19666563; DOI=10.1073/pnas.0905128106;
RA   Ye K., Jia R., Lin J., Ju M., Peng J., Xu A., Zhang L.;
RT   "Structural organization of box C/D RNA-guided RNA methyltransferase.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:13808-13813(2009).
RN   [3] {ECO:0007829|PDB:3PLA}
RP   X-RAY CRYSTALLOGRAPHY (3.15 ANGSTROMS) OF 1-380.
RX   PubMed=21270896; DOI=10.1038/nature09688;
RA   Lin J., Lai S., Jia R., Xu A., Zhang L., Lu J., Ye K.;
RT   "Structural basis for site-specific ribose methylation by box C/D RNA
RT   protein complexes.";
RL   Nature 469:559-563(2011).
RN   [4] {ECO:0007829|PDB:5GIN, ECO:0007829|PDB:5GIO}
RP   X-RAY CRYSTALLOGRAPHY (3.13 ANGSTROMS) OF 3-380.
RX   PubMed=27625427; DOI=10.1073/pnas.1604872113;
RA   Yang Z., Lin J., Ye K.;
RT   "Box C/D guide RNAs recognize a maximum of 10 nt of substrates.";
RL   Proc. Natl. Acad. Sci. U.S.A. 113:10878-10883(2016).
RN   [5] {ECO:0007829|PDB:7XPL}
RP   X-RAY CRYSTALLOGRAPHY (2.21 ANGSTROMS) OF 1-379.
RX   PubMed=36127125; DOI=10.1261/rna.079379.122;
RA   Wang J., Yang Z., Ye K.;
RT   "Methylation guide RNAs without box C/D motifs.";
RL   RNA 28:1597-1605(2022).
CC   -!- INTERACTION:
CC       Q97ZH3; P58032: flpA; NbExp=5; IntAct=EBI-2944135, EBI-2944159;
CC   -!- SIMILARITY: Belongs to the NOP5/NOP56 family.
CC       {ECO:0000256|ARBA:ARBA00009211}.
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DR   EMBL; AE006641; AAK41215.1; -; Genomic_DNA.
DR   PIR; H90244; H90244.
DR   PDB; 3ICX; X-ray; 3.10 A; A/B/C=135-380.
DR   PDB; 3ID5; X-ray; 4.01 A; A/E=1-380.
DR   PDB; 3ID6; X-ray; 2.60 A; A=1-262.
DR   PDB; 3PLA; X-ray; 3.15 A; A/B/K=1-380.
DR   PDB; 5GIN; X-ray; 3.31 A; A/B/K=1-1, A/B/K=4-380.
DR   PDB; 5GIO; X-ray; 3.60 A; A/B/K=1-1, A/B/K=4-380.
DR   PDB; 5GIP; X-ray; 3.13 A; A/B/K/L=1-1, A/B/K/L=4-380.
DR   PDB; 7XPL; X-ray; 2.21 A; A/B=1-379.
DR   PDBsum; 3ICX; -.
DR   PDBsum; 3ID5; -.
DR   PDBsum; 3ID6; -.
DR   PDBsum; 3PLA; -.
DR   PDBsum; 5GIN; -.
DR   PDBsum; 5GIO; -.
DR   PDBsum; 5GIP; -.
DR   AlphaFoldDB; Q97ZH3; -.
DR   SMR; Q97ZH3; -.
DR   DIP; DIP-48938N; -.
DR   IntAct; Q97ZH3; 1.
DR   STRING; 273057.SSO0939; -.
DR   PaxDb; 273057-SSO0939; -.
DR   EnsemblBacteria; AAK41215; AAK41215; SSO0939.
DR   KEGG; sso:SSO0939; -.
DR   PATRIC; fig|273057.12.peg.935; -.
DR   eggNOG; arCOG01923; Archaea.
DR   HOGENOM; CLU_015495_1_0_2; -.
DR   InParanoid; Q97ZH3; -.
DR   PhylomeDB; Q97ZH3; -.
DR   EvolutionaryTrace; Q97ZH3; -.
DR   Proteomes; UP000001974; Chromosome.
DR   GO; GO:0031428; C:box C/D RNP complex; IBA:GO_Central.
DR   GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR   GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR   Gene3D; 1.10.287.4070; -; 1.
DR   Gene3D; 3.30.420.220; -; 1.
DR   Gene3D; 1.10.246.90; Nop domain; 1.
DR   InterPro; IPR045056; Nop56/Nop58.
DR   InterPro; IPR048896; Nop5_56-rel_N.
DR   InterPro; IPR047099; Nop5_N_sf.
DR   InterPro; IPR042239; Nop_C.
DR   InterPro; IPR002687; Nop_dom.
DR   InterPro; IPR036070; Nop_dom_sf.
DR   InterPro; IPR012976; NOSIC.
DR   PANTHER; PTHR10894; NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58; 1.
DR   PANTHER; PTHR10894:SF0; NUCLEOLAR PROTEIN 56; 1.
DR   Pfam; PF01798; Nop; 1.
DR   Pfam; PF21572; Nop5_56-rel_N_Arc; 1.
DR   SMART; SM00931; NOSIC; 1.
DR   SUPFAM; SSF89124; Nop domain; 1.
DR   PROSITE; PS51358; NOP; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:3ICX, ECO:0007829|PDB:3ID5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001974}.
FT   DOMAIN          261..376
FT                   /note="Nop"
FT                   /evidence="ECO:0000259|PROSITE:PS51358"
FT   REGION          373..412
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   412 AA;  46693 MW;  1DDA9C2C5E535ED4 CRC64;
     MMKIYLIEHV IGAVAYDENG NIVDYITNPR DLGKITEELL NNEKGIPFSA TVELLKKVNP
     QEVVVENEAE VPKLQALGYR VSYEPYSKVS RIFRESLPKV AIDIKFASNE EDYYNFLHEL
     SLEYTRRKLR SAAQKRDLLA IQAVRAMDDI DKTINLFSER LREWYSIHFP ELDKLIEDHE
     EYATIVSRFG DRGFLTIDSL KELGFNEQRI NRILDAAKKS IGADISEDDL SAMRMIANTI
     LDLYNIRRNL NNYLEGVMKE VAPNVTALVG PALGARLLSI AGSLDELAKM PASTIQVLGA
     EKALFRALRS GGRPPKHGII FQYPAIHTSP RWQRGKIARA LAAKLAIAAR VDAFSGRFIG
     DQLNEQLKKR IDEIKEKFAQ PPPKKPQQQK PQQPQKQQAK GKKGGKRRGK RK
//