Q97X94 (UPPP_SULSO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Undecaprenyl-diphosphatase
EC=3.6.1.27

Alternative name(s):
Undecaprenyl pyrophosphate phosphatase

Gene names

Name:	uppP
Synonyms:	bacA, upk
Ordered Locus Names:	SSO1860

Organism

Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) [Reference proteome] [HAMAP]

Taxonomic identifier

273057 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus › Sulfolobus solfataricus

Protein attributes

Sequence length	278 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) By similarity. HAMAP-Rule MF_01006
Catalytic activity	Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006
Subcellular location	Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.
Sequence similarities	Belongs to the UppP family.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	dephosphorylation Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	undecaprenyl-diphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 278	278	Undecaprenyl-diphosphatase HAMAP-Rule MF_01006		PRO_0000151254
Regions
	Transmembrane	3 – 23	21	Helical; Potential
	Transmembrane	42 – 62	21	Helical; Potential
	Transmembrane	88 – 108	21	Helical; Potential
	Transmembrane	112 – 132	21	Helical; Potential
	Transmembrane	152 – 172	21	Helical; Potential
	Transmembrane	190 – 210	21	Helical; Potential
	Transmembrane	225 – 245	21	Helical; Potential
	Transmembrane	253 – 273	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q97X94 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 922897405C584460	FASTA	278	29,967
	10 20 30 40 50 60 MNYILIGVIL GIVQGISEWI PISSKTQVLI VSSTLLGLSF NVAYSFGLFM EIGTIAAAIF 70 80 90 100 110 120 YFRSEISGLL KALVRMSSRR EDYLLLKFLV IVTIITGLVG VPLYLFVISL PILGLPMTVL 130 140 150 160 170 180 GVVLLIDGIV IYLSRKNYFP RKGLHDLKLR DIIIVGIAQG LAALPGVSRS GMTTSALILL 190 200 210 220 230 240 GVKPEEAFKL SFISLIPAAL GAISVTVLFS KHEVSQAVHS VSLSGLLISI VVATFVSIFF 250 260 270 INALLRFART NKVVLLVIIL GIMAIISGIL SDIAKGFY

References

[1]

"The complete genome of the crenarchaeon Sulfolobus solfataricus P2." She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J., Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G., Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J., Medina N., Peng X. , Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C., Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T., Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J. Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006641 Genomic DNA. Translation: AAK42048.1.
PIR	A99349.
RefSeq	NP_343258.1. NC_002754.1.
3D structure databases
ProteinModelPortal	Q97X94.
ModBase	Search...
Protein-protein interaction databases
STRING	273057.SSO1860.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAK42048; AAK42048; SSO1860.
GeneID	1453375.
KEGG	sso:SSO1860.
Phylogenomic databases
eggNOG	COG1968.
HOGENOM	HOG000218357.
KO	K06153.
OMA	HMMWALI.
ProtClustDB	PRK00281.
Family and domain databases
HAMAP	MF_01006. Undec_diphosphatase.
InterPro	IPR003824. Bacitracin-R_BacA. [Graphical view]
Pfam	PF02673. BacA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UPPP_SULSO

Accession

Primary (citable) accession number: Q97X94

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 5, 2002
Last sequence update:	October 1, 2001
Last modified:	May 1, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program