Ferredoxin--NADP reductase - Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

Preferred order of sections

Names and origin

Protein names

Recommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2

Gene names

Ordered Locus Names:

SSO2222

Organism

Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

Taxonomic identifier

273057 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	332 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 reduced ferredoxin + NADP⁺ + H⁺ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685
Cofactor	Binds 1 FAD per subunit By similarity. HAMAP MF_01685
Subunit structure	Homodimer By similarity. HAMAP MF_01685
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 332

332

Ferredoxin--NADP reductase HAMAP MF_01685

PRO_0000364991

Sites

Binding site

33

1

FAD By similarity

Binding site

41

1

FAD By similarity

Binding site

46

1

FAD By similarity

Binding site

86

1

FAD; via amide nitrogen and carbonyl oxygen By similarity

Binding site

120

1

FAD; via amide nitrogen By similarity

Binding site

281

1

FAD By similarity

Binding site

324

1

FAD By similarity

Experimental info

Sequence conflict

185

1

F → L in CAB57297. Ref.2

Sequences

Sequence

Length

Mass (Da)

Tools

Q97WJ5 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: 08E580F13F114A08
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FASTA

332

36,542

        10         20         30         40         50         60 
MDEYDIVVIG GGPVGLFGTF YAGLRDMKTL LIDAQDELGG QLVSLYPEKI VYDVGGLAGI 

        70         80         90        100        110        120 
QAYELAQRLI EQAKMFGPDI KVNELADMIE KTNDNMWIVK TDKATYKTKT IFIAAGIGKI 

       130        140        150        160        170        180 
VPSRLGAKGE IEYENRGVYY TVRRKKDFEG KRVLIVGGGD SAVDWALTLA PVAKSVTLIH 

       190        200        210        220        230        240 
RRDQFRAHER SVKELFRVAN VYVWHELKEV KGDGNKVTQA IIFDNRTKEE KVLDVDSVII 

       250        260        270        280        290        300 
SIGYKGDLGN IPKWGVTMKG RDIVVNGRME TNLPGVYAGG DIVQMEGSPK LALIAVGFAH 

       310        320        330 
AAIAISVAKK YVEPNASLFA GHSSEMDKFK PK

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Arcari P., Masullo M., Masullo L., Bocchini V. Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"The complete genome of the crenarchaeon Sulfolobus solfataricus P2." She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J., Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G., Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J., Medina N., Peng X. Van der Oost J. Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001) [PubMed: 11427726] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ243598 Genomic DNA. Translation: CAB57297.1. AE006641 Genomic DNA. Translation: AAK42391.1.
PIR	H90391.
RefSeq	NP_343601.1. NC_002754.1.
3D structure databases
HSSP	HSSP built from PDB template 2A87 based on UniProtKB P52214.
ProteinModelPortal	Q97WJ5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1453718.
GenomeReviews	Gene locus SSO2222 in contig AE006641_GR.
KEGG	sso:SSO2222.
NMPDR	fig\|273057.1.peg.2024.
Phylogenomic databases
HOGENOM	HBG669726.
OMA	FQVFELG.
ProtClustDB	CLSK803258.
Enzyme and pathway databases
BioCyc	SSOL273057:SSO2222-MONOMER.
Family and domain databases
HAMAP	MF_01685. FENR2. [Tree]
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR022890. Fd--NADP_Rdtase_type_2. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. [Graphical view]
KO	K00384.
PANTHER	PTHR22912:SF53. PTHR22912:SF53. 1 hit.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
ProtoNet	Search...

Entry information

Entry name

FENR_SULSO

Accession

Primary (citable) accession number: Q97WJ5
Secondary accession number(s): Q9UXN1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	October 1, 2001
Last modified:	November 16, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Sites

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information

Relevant documents