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Q97WE5 (PGMI_SULSO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Bifunctional phosphoglucose/phosphomannose isomerase
Alternative name(s):
Glucose-6-phosphate isomerase
Short name=GPI
EC=5.3.1.9
Mannose-6-phosphate isomerase
EC=5.3.1.8
Phosphoglucose isomerase
Short name=PGI
Phosphomannose isomerase
Short name=PMI
Gene names
Ordered Locus Names:SSO2281
OrganismSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) [Reference proteome] [HAMAP]
Taxonomic identifier273057 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length296 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency By similarity.

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate.

D-mannose 6-phosphate = D-fructose 6-phosphate.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the PGI/PMI family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 296296Bifunctional phosphoglucose/phosphomannose isomerase
PRO_0000227796

Sites

Active site1921Proton acceptor By similarity
Active site2081Proton donor By similarity
Active site2861Proton acceptor Probable

Sequences

Sequence LengthMass (Da)Tools
Q97WE5 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: E4EA89F3BA2F215B

FASTA29633,141
        10         20         30         40         50         60 
MDEIYLNWDK MFDEAFRIPI HEIKNDNIVF SGIGGSGIVG EIANILGVEL SFKRKFTGKE 

        70         80         90        100        110        120 
SLIAVSYSGT TSETINDVEN AVKAGSEVII ITSGGILEKL AKEKSLKLIK IPSGFQTRYA 

       130        140        150        160        170        180 
FPYLFTPLIK MTTKRRGIKI NEMELKEGVI EAKEQIKADA TRLAELLINR IPVIYSSKYL 

       190        200        210        220        230        240 
AIAKRFKQEI NENAKHPAFY GEIPEINHNE IESYVHGPSL VSVIVESSEI DKITEDVLNS 

       250        260        270        280        290 
IVIKPYFNSD EKNISSLLAL AGVTSLEMAK KLNEKPDKLY NIPKARQLTS NLFKIN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006641 Genomic DNA. Translation: AAK42443.1.
PIRD90398.
RefSeqNP_343653.1. NC_002754.1.

3D structure databases

ProteinModelPortalQ97WE5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273057.SSO2281.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK42443; AAK42443; SSO2281.
GeneID1453770.
KEGGsso:SSO2281.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000270998.
KOK15916.
OMANWIEGSE.

Enzyme and pathway databases

BioCycSSOL273057:GCH2-2128-MONOMER.

Family and domain databases

InterProIPR011857. Glu6P/Mann6P_isomerase.
IPR019490. Glu6P/Mann6P_isomerase_C.
[Graphical view]
PfamPF10432. bact-PGI_C. 1 hit.
[Graphical view]
TIGRFAMsTIGR02128. G6PI_arch. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGMI_SULSO
AccessionPrimary (citable) accession number: Q97WE5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: October 1, 2001
Last modified: May 14, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families