ID   Q97VA7_SACS2            Unreviewed;       440 AA.
AC   Q97VA7;
DT   01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2001, sequence version 1.
DT   27-MAR-2024, entry version 114.
DE   SubName: Full=4-aminobutyrate aminotransferase (GabT-1) {ECO:0000313|EMBL:AAK42838.1};
DE            EC=2.6.1.19 {ECO:0000313|EMBL:AAK42838.1};
GN   Name=gabT-1 {ECO:0000313|EMBL:AAK42838.1};
GN   OrderedLocusNames=SSO2727 {ECO:0000313|EMBL:AAK42838.1};
OS   Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
OS   (Sulfolobus solfataricus).
OC   Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Saccharolobus.
OX   NCBI_TaxID=273057 {ECO:0000313|EMBL:AAK42838.1, ECO:0000313|Proteomes:UP000001974};
RN   [1] {ECO:0000313|Proteomes:UP000001974}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2
RC   {ECO:0000313|Proteomes:UP000001974};
RX   PubMed=11427726; DOI=10.1073/pnas.141222098;
RA   She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J.,
RA   Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G.,
RA   Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J.,
RA   Medina N., Peng X., Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C.,
RA   Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T.,
RA   Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J.;
RT   "The complete genome of the crenarchaeon Sulfolobus solfataricus P2.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|RuleBase:RU003560}.
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DR   EMBL; AE006641; AAK42838.1; -; Genomic_DNA.
DR   PIR; G90447; G90447.
DR   RefSeq; WP_009991724.1; NC_002754.1.
DR   AlphaFoldDB; Q97VA7; -.
DR   STRING; 273057.SSO2727; -.
DR   PaxDb; 273057-SSO2727; -.
DR   EnsemblBacteria; AAK42838; AAK42838; SSO2727.
DR   GeneID; 72911296; -.
DR   KEGG; sso:SSO2727; -.
DR   PATRIC; fig|273057.12.peg.2807; -.
DR   eggNOG; arCOG00915; Archaea.
DR   HOGENOM; CLU_016922_10_0_2; -.
DR   InParanoid; Q97VA7; -.
DR   PhylomeDB; Q97VA7; -.
DR   Proteomes; UP000001974; Chromosome.
DR   GO; GO:0034386; F:4-aminobutyrate:2-oxoglutarate transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042802; F:identical protein binding; IBA:GO_Central.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IBA:GO_Central.
DR   CDD; cd00610; OAT_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR005814; Aminotrans_3.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR11986; AMINOTRANSFERASE CLASS III; 1.
DR   PANTHER; PTHR11986:SF58; LEUCINE_METHIONINE RACEMASE; 1.
DR   Pfam; PF00202; Aminotran_3; 1.
DR   PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 2.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000313|EMBL:AAK42838.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|RuleBase:RU003560};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001974};
KW   Transferase {ECO:0000313|EMBL:AAK42838.1}.
SQ   SEQUENCE   440 AA;  48781 MW;  44B2CFDCB62EA857 CRC64;
     MEENLDSSVL EAPIINVTPP GSKSLKLLKD QEEYETSAIN YPKYFKIAID KAQGSTVTDV
     DGNVYIDLVT GISVVNLGHN NPFVRKRVQE QLEKVWHTLE VPTEIRVNFS KKLLSTLGMR
     AKLLFTTTGA DAVEAAVKIA RFITGKKTII AFEGSYHGIT AGTLGLTGAN RFKEFQPFFD
     DRVVKFPYPY PYRCPFKDCL NETLSLLDYA MSNPGYLGGD VAGILVEPIQ GEGGYVVPPK
     GFLKGLKELA EKYSVPLIVD EVQTGVGRTG KMWAYQWENI EPDIVTISKA IGEGIPVSMV
     AYREDFDKLP TGFHLGTYRG NPLGLAAGLA SLEFIESHNI LSRVERLGRK ALELLKEVQN
     PHVGDIRGLG FMIGIELVKD SKEPWSEGTK VVIERALKRG LLVYKAGRWD NVIRLMPPLT
     IPESLLDRAI EILKIILNTL
//