Reviewed,
UniProtKB/Swiss-Prot Q97TN4 (ALF1_CLOAB)
Last modified
January 19, 2010.
Version 45.
History...
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90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Fructose-bisphosphate aldolase class 1 EC=4.1.2.13 Alternative name(s): Fructose-biphosphate aldolase class I Short name=FBP aldolase | ||||
| Gene names |
| ||||
| Encoded on | Plasmid pSOL1 | ||||
| Organism | Clostridium acetobutylicum [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 1488 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium |
Protein attributes
| Sequence length | 295 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. HAMAP MF_00729 |
| Pathway | Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4. HAMAP MF_00729 |
| Sequence similarities | Belongs to the class I fructose-bisphosphate aldolase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Glycolysis |
| Ligand | Schiff base |
| Molecular function | Lyase |
| Technical term | Complete proteome Plasmid |
| Gene Ontology (GO) | |
| Biological process | glycolysis Inferred from electronic annotation. Source: HAMAP |
| Molecular function | fructose-bisphosphate aldolase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 295 | 295 | Fructose-bisphosphate aldolase class 1 HAMAP MF_00729 | PRO_0000216899 | |||||
Sites | |||||||||
| Active site | 176 | 1 | Proton acceptor By similarity | ||||||
| Active site | 213 | 1 | Schiff-base intermediate with dihydroxyacetone-P By similarity | ||||||
Sequences
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References
| [1] | "Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum." Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R., Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F., Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V., Smith D.R. J. Bacteriol. 183:4823-4838(2001) [PubMed: 11466286] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE001438 Genomic DNA. Translation: AAK76810.1. |
| RefSeq | NP_149228.1. |
3D structure databases | |
| SMR | Q97TN4. Positions 1-295. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1116069. |
| GenomeReviews | Gene locus CA_P0064 in contig AE001438_GR. |
| KEGG | cac:CA_P0064. |
| NMPDR | fig|272562.1.peg.63. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG307137. |
| OMA | GTKMRSV. |
Enzyme and pathway databases | |
| BioCyc | CACE272562:CAP0064-MONOMER. |
| BRENDA | 4.1.2.13. 2866. |
Family and domain databases | |
| HAMAP | MF_00729. FBP_aldolase_1. [Tree] |
| InterPro | IPR000741. Aldolase_I. IPR013785. Aldolase_TIM. [Graphical view] |
| Gene3D | G3DSA:3.20.20.70. Aldolase_TIM. 1 hit. |
| PANTHER | PTHR11627. Aldolase_I. 1 hit. |
| Pfam | PF00274. Glycolytic. 2 hits. [Graphical view] |
| PROSITE | PS00158. ALDOLASE_CLASS_I. False negative. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | ALF1_CLOAB | ||||||||
| Accession | Primary (citable) accession number: Q97TN4 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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