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Q97SA9 (LACG1_STRPN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
6-phospho-beta-galactosidase 1

EC=3.2.1.85
Alternative name(s):
Beta-D-phosphogalactoside galactohydrolase 1
Short name=PGALase 1
P-beta-Gal 1
Short name=PBG 1
Gene names
Name:lacG1
Synonyms:lacG-1
Ordered Locus Names:SP_0477
OrganismStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) [Complete proteome] [HAMAP]
Taxonomic identifier170187 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length470 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

A 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol. HAMAP-Rule MF_01574

Pathway

Carbohydrate metabolism; lactose degradation; D-galactose 6-phosphate and beta-D-glucose from lactose 6-phosphate: step 1/1. HAMAP-Rule MF_01574

Sequence similarities

Belongs to the glycosyl hydrolase 1 family.

Ontologies

Keywords
   Molecular functionGlycosidase
Hydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processlactose catabolic process via tagatose-6-phosphate

Inferred from electronic annotation. Source: InterPro

   Molecular_function6-phospho-beta-galactosidase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4704706-phospho-beta-galactosidase 1 HAMAP-Rule MF_01574
PRO_0000260730

Sites

Active site1641Proton donor By similarity
Active site3781Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q97SA9 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: 964D7022454360C6

FASTA47054,633
        10         20         30         40         50         60 
MENLQVKALP KEFLLGTATA AYQVEGATRV DGKGINMWDV YLQENSPFLP DPASDFYYRY 

        70         80         90        100        110        120 
EEDIALAAEH GLQALRLSIS WVRIFPDIDG DANVLAVHYY HRVFQSCLKH NVIPFVSLHH 

       130        140        150        160        170        180 
FDSPQKMLET GDWLNRENID RFIRYARFCF QEFTEVKHWF TINELMSLAA GQYIGGQFPP 

       190        200        210        220        230        240 
NHHFQLSEAI QANHNMLLAH ALAVLEFHQL GIEGKVGCIH ALKPGYPIDG QKENILAAKR 

       250        260        270        280        290        300 
YDVYNNKFLL DGTFLGYYSE DTLFHLNQIL EANNSSFIIE DGDLEIMKRA APLNTMFGMN 

       310        320        330        340        350        360 
YYRSEFIREY KGENRQEFNS TGIKGQSSFK LNALGEFVKK PGIPTTDWDW NIYPQGLFDM 

       370        380        390        400        410        420 
LLRIKEEYPQ HPVIYLTENG TALKEVKPEG ENDIIDDSKR IRYIEQHLHK VLEARDRGVN 

       430        440        450        460        470 
IQGYFIWSLQ DQFSWANGYN KRYGLFFVDY ETQKRYIKKS ALWVKGLKRN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005672 Genomic DNA. Translation: AAK74636.1.
PIRC95055.
RefSeqNP_344996.1. NC_003028.3.

3D structure databases

ProteinModelPortalQ97SA9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING170187.SP_0477.

Protein family/group databases

CAZyGH1. Glycoside Hydrolase Family 1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK74636; AAK74636; SP_0477.
GeneID930415.
KEGGspn:SP_0477.
PATRIC19705307. VBIStrPne105772_0499.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2723.
HOGENOMHOG000088632.
KOK01220.
OMALAVRYYH.
OrthoDBEOG60658J.
ProtClustDBPRK13511.

Enzyme and pathway databases

BioCycSPNE170187:GHGN-483-MONOMER.
UniPathwayUPA00542; UER00605.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
HAMAPMF_01574. LacG.
InterProIPR005928. 6P-beta-galactosidase.
IPR001360. Glyco_hydro_1.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR10353. PTHR10353. 1 hit.
PfamPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSPR00131. GLHYDRLASE1.
SUPFAMSSF51445. SSF51445. 1 hit.
TIGRFAMsTIGR01233. lacG. 1 hit.
ProtoNetSearch...

Entry information

Entry nameLACG1_STRPN
AccessionPrimary (citable) accession number: Q97SA9
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: October 1, 2001
Last modified: February 19, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries