Q97QP1 (Q97QP1_STRPN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative lipoate-protein ligase EMBL AAK75269.1

Gene names

Ordered Locus Names:

SP_1160

Organism

Streptococcus pneumoniae TIGR4 [Complete proteome] EMBL AAK75269.1

Taxonomic identifier

170187 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	329 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	ATP + lipoate = diphosphate + lipoyl-AMP. SAAS SAAS004562 Lipoyl-AMP + protein = protein N(6)-(lipoyl)lysine + AMP. SAAS SAAS004562
Pathway	Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 1/2. SAAS SAAS004562 Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2. SAAS SAAS004562

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS004562
Ligand	ATP-binding SAAS SAAS004562 Nucleotide-binding
Molecular function	Ligase EMBL AAK75269.1 Transferase SAAS SAAS004562
Technical term	3D-structure PDB 1VQZ Complete proteome
Gene Ontology (GO)
Biological process	protein lipoylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: UniProtKB-KW transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q97QP1 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 423F3AEAB00B5086	FASTA	329	37,736
	10 20 30 40 50 60 MKYIINHSND TAFNIALEEY AFKHLLDEDQ IFLLWINKPS IIVGRHQNTI EEINRDYVRE 70 80 90 100 110 120 NGIEVVRRIS GGGAVYHDLN NLNYTIISKE DENKAFDFKS FSTPVINTLA QLGVKAEFTG 130 140 150 160 170 180 RNDLEIDGKK FCGNAQAYIN GRIMHHGCLL FDVDLSVLAN ALKVSKDKFE SKGVKSVRAR 190 200 210 220 230 240 VTNIINELPK KITVEKFRDL LLEYMKKEYP EMTEYVFSEE ELAEINRIKD TKFGTWDWNY 250 260 270 280 290 300 GKSPEFNVRR GIKFTSGKVE VFANVTESKI QDIKIYGDFF GIEDVAAVED VLRGVKYERE 310 320 DVLKALKTID ITRYFAGISR EEIAEAVVG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of a virulent isolate of Streptococcus pneumoniae." Tettelin H., Nelson K.E., Paulsen I.T., Eisen J.A., Read T.D., Peterson S., Heidelberg J., DeBoy R.T., Haft D.H., Dodson R.J., Durkin A.S., Gwinn M., Kolonay J.F., Nelson W.C., Peterson J.D., Umayam L.A., White O., Salzberg S.L. , Lewis M.R., Radune D., Holtzapple E., Khouri H., Wolf A.M., Utterback T.R., Hansen C.L., McDonald L.A., Feldblyum T.V., Angiuoli S., Dickinson T., Hickey E.K., Holt I.E., Loftus B.J., Yang F., Smith H.O., Venter J.C., Dougherty B.A., Morrison D.A., Hollingshead S.K., Fraser C.M. Science 293:498-506(2001) [PubMed: 11463916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-334 / TIGR4.
[2]	"Crystal structure of putative Lipoate-protein ligase (np_345629.1) from Streptococcus pneumoniae tigr4 at 1.99 A resolution." Joint Center for Structural Genomics (JCSG) Submitted (JAN-2005) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.99 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE005672 Genomic DNA. Translation: AAK75269.1.

PIR

D95134.

RefSeq

NP_345629.1. NC_003028.3.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1VQZ	X-ray	1.99	A	1-329	[»]

ProteinModelPortal

Q97QP1.

SMR

Q97QP1. Positions 1-329.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

EBSTRT00000025583; EBSTRP00000024675; EBSTRG00000025583.

GeneID

931674.

GenomeReviews

Gene locus SP_1160 in contig AE005672_GR.

KEGG

spn:SP_1160.

PATRIC

19706723. VBIStrPne105772_1206.

TIGR

SP_1160.

Phylogenomic databases

GeneTree

EBGT00050000026921.

HOGENOM

HBG715377.

OMA

SEERYQN.

ProtClustDB

CLSK877149.

Enzyme and pathway databases

BioCyc

SPNE170187-1:SP_1160-MONOMER.

Family and domain databases

InterPro

IPR004143. BPL_LipA_LipB.
IPR005107. CO_DH_flav_C.
IPR019491. Lipoate_protein_ligase_C.
IPR004562. LipoylTrfase_LipoateP_Ligase.
[Graphical view]

Gene3D

G3DSA:3.30.390.50. CO_DH_flav_C. 1 hit.

KO

K03800.

Pfam

PF03099. BPL_LplA_LipB. 1 hit.
PF10437. Lip_prot_lig_C. 1 hit.
[Graphical view]

TIGRFAMs

TIGR00545. Lipoyltrans. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q97QP1_STRPN

Accession

Primary (citable) accession number: Q97QP1

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2001
Last sequence update:	October 1, 2001
Last modified:	January 25, 2012
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)