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Q97QL9 (LACG2_STRPN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phospho-beta-galactosidase 2
EC=3.2.1.85
Alternative name(s):
Beta-D-phosphogalactoside galactohydrolase 2
Short name=PGALase 2
P-beta-Gal 2
Short name=PBG 2
Gene names
Name:lacG2
Synonyms:lacG-2
Ordered Locus Names:SP_1184
OrganismStreptococcus pneumoniae [Complete proteome] [HAMAP]
Taxonomic identifier1313 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length468 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

A 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol. HAMAP MF_01574

Pathway

Carbohydrate metabolism; lactose degradation; D-galactose 6-phosphate and beta-D-glucose from lactose 6-phosphate: step 1/1. HAMAP MF_01574

Sequence similarities

Belongs to the glycosyl hydrolase 1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4684686-phospho-beta-galactosidase 2 HAMAP MF_01574
PRO_0000260731

Sites

Active site1601Proton donor By similarity
Active site3751Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q97QL9 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: BCCB944228B0E90F

FASTA46853,914
        10         20         30         40         50         60 
MTKTLPKDFI FGGATAAYQA EGATHTDGKG PVAWDKYLED NYWYTAEPAS DFYNRYPVDL 

        70         80         90        100        110        120 
KLAEEYGVNG IRISIAWSRI FPTGYGQVNA KGVEFYHNLF AECHKRHVEP FVTLHHFDTP 

       130        140        150        160        170        180 
EALHSNGDFL NRENIEHFVD YAAFCFEEFP EVNYWTTFNE IGPIGDGQYL VGKFPPGIQY 

       190        200        210        220        230        240 
DLAKVFQSHH NMMVSHARAV KLYKEKGYKG EIGVVHALPT KYPLDPENPA DVRAAELEDI 

       250        260        270        280        290        300 
IHNKFILDAT YLGRYSAETM EGVNHILLVN GGSLDLREED FTALEAAKDL NDFLGINYYM 

       310        320        330        340        350        360 
SDWMEAFDGE TEIIHNGKGE KGSSKYQIKG VGRRVAPDYV PRTDWDWIIY PQGLYDQIMR 

       370        380        390        400        410        420 
VKKDYPNYKK IYITENGLGY KDEFVDNTVY DDGRIDYVKQ HLEVLSDAIA DGANVKGYFI 

       430        440        450        460 
WSLMDVFSWS NGYEKRYGLF YVDFETQERY PKKSAHWYKK VAETQIID

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE005672 Genomic DNA. Translation: AAK75293.1.
PIRD95137.
RefSeqNP_345653.1. NC_003028.3.

3D structure databases

HSSPHSSP built from PDB template 1PBG based on UniProtKB P11546.
ProteinModelPortalQ97QL9.
SMRQ97QL9. Positions 1-468.
ModBaseSearch...

Protein family/group databases

CAZyGH1. Glycoside Hydrolase Family 1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTRT00000025160; EBSTRP00000024252; EBSTRG00000025160.
GeneID931698.
GenomeReviewsGene locus SP_1184 in contig AE005672_GR.
KEGGspn:SP_1184.
PATRIC19706767. VBIStrPne105772_1228.
TIGRSP_1184.

Phylogenomic databases

GeneTreeEBGT00050000027409.
HOGENOMHBG316462.
OMAPTGYGEV.
ProtClustDBPRK13511.

Enzyme and pathway databases

BioCycSPNE170187-1:SP_1184-MONOMER.

Family and domain databases

HAMAPMF_01574. LacG.
[Tree]
InterProIPR005928. 6P-beta-galactosidase.
IPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_subgr_catalytic.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
Gene3DG3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
KOK01220.
PANTHERPTHR10353. Glyco_hydro_1. 1 hit.
PfamPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSPR00131. GLHYDRLASE1.
SUPFAMSSF51445. Glyco_hydro_cat. 1 hit.
TIGRFAMsTIGR01233. LacG. 1 hit.
PROSITEPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLACG2_STRPN
AccessionPrimary (citable) accession number: Q97QL9
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: October 1, 2001
Last modified: January 25, 2012
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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