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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei38NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciSPNE170187:G1FZB-1227-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:SP_1212
OrganismiStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Taxonomic identifieri170187 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000585 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001219151 – 292tRNA pseudouridine synthase BAdd BLAST292

Proteomic databases

PRIDEiQ97QJ3

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
SP_1748A0A0H2URH94EBI-6473797,EBI-6473801

Protein-protein interaction databases

IntActiQ97QJ3, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ97QJ3
SMRiQ97QJ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T Bacteria
COG0130 LUCA
HOGENOMiHOG000231225
KOiK03177
OMAiVDCSKGT

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

Q97QJ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGIINLKKE AGMTSHDAVF KLRKILGTKK IGHGGTLDPD VVGVLPIAVG
60 70 80 90 100
KATRMVEFMQ DEGKIYEGEI TLGYSTKTED ASGEVVAETP VLSLLDEKLV
110 120 130 140 150
DEAIASLTGP ITQIPPMYSA VKVNGRKLYE YARAGQEVER PERQVTIYQF
160 170 180 190 200
ERTSPISYDG QLARFTFRVK CSKGTYIRTL SVDLGEKLGY AAHMSHLTRT
210 220 230 240 250
SAAGLQLEDA LALEEIAEKV EAGQLDFLHP LEIGTGDLVK VFLSPEEATE
260 270 280 290
VRFGRFIELD QTDKELAAFE DDKLLAILEK RGNLYKPRKV FS
Length:292
Mass (Da):32,271
Last modified:October 1, 2001 - v1
Checksum:iB7A192469C4BC168
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005672 Genomic DNA Translation: AAK75319.1
PIRiF95140
RefSeqiWP_001013240.1, NZ_AKVY01000001.1

Genome annotation databases

EnsemblBacteriaiAAK75319; AAK75319; SP_1212
KEGGispn:SP_1212

Similar proteinsi

Entry informationi

Entry nameiTRUB_STRPN
AccessioniPrimary (citable) accession number: Q97QJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2003
Last sequence update: October 1, 2001
Last modified: May 23, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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