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Q97QH2

- Q97QH2_STRPN

UniProt

Q97QH2 - Q97QH2_STRPN

Protein
Submitted name:

Amino acid ABC transporter, amino acid-binding protein/permease protein

Gene

SP_1241

Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (01 Oct 2001)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei315 – 3151Acetate 1Imported
    Binding sitei332 – 3321Acetate 1; via carbonyl oxygenImported
    Binding sitei335 – 3351Acetate 2; via amide nitrogenImported
    Binding sitei338 – 3381Acetate 3; via amide nitrogenImported
    Binding sitei340 – 3401Acetate 2Imported
    Binding sitei346 – 3461Chloride 1; via amide nitrogenImported
    Binding sitei383 – 3831Chloride 2; via amide nitrogenImported
    Binding sitei403 – 4031Chloride 3; via amide nitrogenImported

    GO - Molecular functioni

    1. transporter activity Source: InterPro

    Keywords - Biological processi

    TransportSAAS annotation

    Enzyme and pathway databases

    BioCyciSPNE170187:GHGN-1245-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Amino acid ABC transporter, amino acid-binding protein/permease proteinImported
    Gene namesi
    Ordered Locus Names:SP_1241Imported
    OrganismiStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)Imported
    Taxonomic identifieri170187 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000000585: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Cell membraneSAAS annotation, Membrane

    Interactioni

    Protein-protein interaction databases

    STRINGi170187.SP_1241.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4OENX-ray1.65A/B266-487[»]
    ProteinModelPortaliQ97QH2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni274 – 2774Acetate 1 bindingImported

    Sequence similaritiesi

    Contains ABC transmembrane type-1 domain.SAAS annotation
    Contains ABC transmembrane type-domain.SAAS annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000267554.
    KOiK02029.
    K02030.
    OMAiMTFPGFD.
    OrthoDBiEOG6MM1R5.

    Family and domain databases

    Gene3Di1.10.3720.10. 1 hit.
    InterProiIPR010065. AA_ABC_transptr_permease_3TM.
    IPR000515. MetI-like.
    IPR001638. SBP_bac_3.
    [Graphical view]
    PfamiPF00528. BPD_transp_1. 1 hit.
    PF00497. SBP_bac_3. 2 hits.
    [Graphical view]
    SMARTiSM00062. PBPb. 2 hits.
    [Graphical view]
    SUPFAMiSSF161098. SSF161098. 1 hit.
    TIGRFAMsiTIGR01726. HEQRo_perm_3TM. 1 hit.
    PROSITEiPS50928. ABC_TM1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q97QH2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKKKFLAFLL ILFPIFSLGI AKAETIKIVS DTAYAPFEFK DSDQTYKGID    50
    VDIINKVAEI KGWNIQMSYP GFDAAVNAVQ AGQADAIMAG MTKTKEREKV 100
    FTMSDTYYDT KVVIATTKSH KISKYDQLTG KTVGVKNGTA AQRFLETIKD 150
    KYGFTIKTFD TGDLMNNSLS AGAIDAMMDD KPVIEYAINQ GQDLHIEMDG 200
    EAVGSFAFGV KKGSKYEHLV TEFNQALSEM KKDGSLDKII KKWTASSSSA 250
    VPTTTTLAGL KAIPVKAKYI IASDSSFAPF VFQNSSNQYT GIDMELIKAI 300
    AKDQGFEIEI TNPGFDAAIS AVQAGQADGI IAGMSVTDAR KATFDFSESY 350
    YTANTILGVK ESSNIASYED LKGKTVGVKN GTASQTFLTE NQSKYGYKIK 400
    TFADGSSMYD SLNTGAIDAV MDDEPVLKYS ISQGQKLKTP ISGTPIGETA 450
    FAVKKGANPE LIEMFNNGLA NLKANGEFQK ILDKYLASES STASTSTVDE 500
    TTLWGLLQNN YKQLLSGLGI TLALALISFA IAIVIGIIFG MFSVSPYKSL 550
    RVISEIFVDV IRGIPLMILA AFIFWGIPNF IESITGQQSP INDFVAGTIA 600
    LSLNAAAYIA EIVRGGIQAV PVGQMEASRS LGISYGKTMR KIILPQATKL 650
    MLPNFVNQFV IALKDTTIVS AIGLVELFQT GKIIIARNYQ SFKMYAILAI 700
    FYLVIITLLT RLAKRLEKRI R 721
    Length:721
    Mass (Da):78,388
    Last modified:October 1, 2001 - v1
    Checksum:i7BBFB7BB4A06FCF0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005672 Genomic DNA. Translation: AAK75346.1.
    PIRiA95144.
    RefSeqiNP_345706.1. NC_003028.3.

    Genome annotation databases

    EnsemblBacteriaiAAK75346; AAK75346; SP_1241.
    GeneIDi931754.
    KEGGispn:SP_1241.
    PATRICi19706875. VBIStrPne105772_1282.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005672 Genomic DNA. Translation: AAK75346.1 .
    PIRi A95144.
    RefSeqi NP_345706.1. NC_003028.3.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4OEN X-ray 1.65 A/B 266-487 [» ]
    ProteinModelPortali Q97QH2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 170187.SP_1241.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK75346 ; AAK75346 ; SP_1241 .
    GeneIDi 931754.
    KEGGi spn:SP_1241.
    PATRICi 19706875. VBIStrPne105772_1282.

    Phylogenomic databases

    HOGENOMi HOG000267554.
    KOi K02029.
    K02030.
    OMAi MTFPGFD.
    OrthoDBi EOG6MM1R5.

    Enzyme and pathway databases

    BioCyci SPNE170187:GHGN-1245-MONOMER.

    Family and domain databases

    Gene3Di 1.10.3720.10. 1 hit.
    InterProi IPR010065. AA_ABC_transptr_permease_3TM.
    IPR000515. MetI-like.
    IPR001638. SBP_bac_3.
    [Graphical view ]
    Pfami PF00528. BPD_transp_1. 1 hit.
    PF00497. SBP_bac_3. 2 hits.
    [Graphical view ]
    SMARTi SM00062. PBPb. 2 hits.
    [Graphical view ]
    SUPFAMi SSF161098. SSF161098. 1 hit.
    TIGRFAMsi TIGR01726. HEQRo_perm_3TM. 1 hit.
    PROSITEi PS50928. ABC_TM1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-334 / TIGR4Imported.
    2. "Crystal structure of the second substrate binding domain of a putative amino acid ABC transporter from Streptococcus pneumoniae Canada MDR_19A."
      Stogios P.J., Wawrzak Z., Kudritska M., Yim V., Savchenko A., Anderson W.F.
      Submitted (JAN-2014) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) OF 266-487.

    Entry informationi

    Entry nameiQ97QH2_STRPN
    AccessioniPrimary (citable) accession number: Q97QH2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2001
    Last sequence update: October 1, 2001
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteomeImported

    External Data

    Dasty 3