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Q97QH2

- Q97QH2_STRPN

UniProt

Q97QH2 - Q97QH2_STRPN

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Protein
Submitted name:

Amino acid ABC transporter, amino acid-binding protein/permease protein

Gene
SP_1241
Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei315 – 3151Acetate 1Imported
Binding sitei332 – 3321Acetate 1; via carbonyl oxygenImported
Binding sitei335 – 3351Acetate 2; via amide nitrogenImported
Binding sitei338 – 3381Acetate 3; via amide nitrogenImported
Binding sitei340 – 3401Acetate 2Imported
Binding sitei346 – 3461Chloride 1; via amide nitrogenImported
Binding sitei383 – 3831Chloride 2; via amide nitrogenImported
Binding sitei403 – 4031Chloride 3; via amide nitrogenImported

GO - Molecular functioni

  1. transporter activity Source: InterPro
Complete GO annotation...

Keywords - Biological processi

TransportSAAS annotations

Enzyme and pathway databases

BioCyciSPNE170187:GHGN-1245-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Amino acid ABC transporter, amino acid-binding protein/permease proteinImported
Gene namesi
Ordered Locus Names:SP_1241Imported
OrganismiStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)Imported
Taxonomic identifieri170187 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000585: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotations, Membrane

Interactioni

Protein-protein interaction databases

STRINGi170187.SP_1241.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4OENX-ray1.65A/B266-487[»]
ProteinModelPortaliQ97QH2.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni274 – 2774Acetate 1 bindingImported

Sequence similaritiesi

Contains ABC transmembrane type-1 domain.SAAS annotations
Contains ABC transmembrane type-domain.SAAS annotations

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

HOGENOMiHOG000267554.
KOiK02029.
K02030.
OMAiMTFPGFD.
OrthoDBiEOG6MM1R5.

Family and domain databases

Gene3Di1.10.3720.10. 1 hit.
InterProiIPR010065. AA_ABC_transptr_permease_3TM.
IPR000515. MetI-like.
IPR001638. SBP_bac_3.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
PF00497. SBP_bac_3. 2 hits.
[Graphical view]
SMARTiSM00062. PBPb. 2 hits.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
TIGRFAMsiTIGR01726. HEQRo_perm_3TM. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q97QH2-1 [UniParc]FASTAAdd to Basket

« Hide

MKKKFLAFLL ILFPIFSLGI AKAETIKIVS DTAYAPFEFK DSDQTYKGID    50
VDIINKVAEI KGWNIQMSYP GFDAAVNAVQ AGQADAIMAG MTKTKEREKV 100
FTMSDTYYDT KVVIATTKSH KISKYDQLTG KTVGVKNGTA AQRFLETIKD 150
KYGFTIKTFD TGDLMNNSLS AGAIDAMMDD KPVIEYAINQ GQDLHIEMDG 200
EAVGSFAFGV KKGSKYEHLV TEFNQALSEM KKDGSLDKII KKWTASSSSA 250
VPTTTTLAGL KAIPVKAKYI IASDSSFAPF VFQNSSNQYT GIDMELIKAI 300
AKDQGFEIEI TNPGFDAAIS AVQAGQADGI IAGMSVTDAR KATFDFSESY 350
YTANTILGVK ESSNIASYED LKGKTVGVKN GTASQTFLTE NQSKYGYKIK 400
TFADGSSMYD SLNTGAIDAV MDDEPVLKYS ISQGQKLKTP ISGTPIGETA 450
FAVKKGANPE LIEMFNNGLA NLKANGEFQK ILDKYLASES STASTSTVDE 500
TTLWGLLQNN YKQLLSGLGI TLALALISFA IAIVIGIIFG MFSVSPYKSL 550
RVISEIFVDV IRGIPLMILA AFIFWGIPNF IESITGQQSP INDFVAGTIA 600
LSLNAAAYIA EIVRGGIQAV PVGQMEASRS LGISYGKTMR KIILPQATKL 650
MLPNFVNQFV IALKDTTIVS AIGLVELFQT GKIIIARNYQ SFKMYAILAI 700
FYLVIITLLT RLAKRLEKRI R 721
Length:721
Mass (Da):78,388
Last modified:October 1, 2001 - v1
Checksum:i7BBFB7BB4A06FCF0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005672 Genomic DNA. Translation: AAK75346.1.
PIRiA95144.
RefSeqiNP_345706.1. NC_003028.3.

Genome annotation databases

EnsemblBacteriaiAAK75346; AAK75346; SP_1241.
GeneIDi931754.
KEGGispn:SP_1241.
PATRICi19706875. VBIStrPne105772_1282.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005672 Genomic DNA. Translation: AAK75346.1 .
PIRi A95144.
RefSeqi NP_345706.1. NC_003028.3.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4OEN X-ray 1.65 A/B 266-487 [» ]
ProteinModelPortali Q97QH2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 170187.SP_1241.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK75346 ; AAK75346 ; SP_1241 .
GeneIDi 931754.
KEGGi spn:SP_1241.
PATRICi 19706875. VBIStrPne105772_1282.

Phylogenomic databases

HOGENOMi HOG000267554.
KOi K02029.
K02030.
OMAi MTFPGFD.
OrthoDBi EOG6MM1R5.

Enzyme and pathway databases

BioCyci SPNE170187:GHGN-1245-MONOMER.

Family and domain databases

Gene3Di 1.10.3720.10. 1 hit.
InterProi IPR010065. AA_ABC_transptr_permease_3TM.
IPR000515. MetI-like.
IPR001638. SBP_bac_3.
[Graphical view ]
Pfami PF00528. BPD_transp_1. 1 hit.
PF00497. SBP_bac_3. 2 hits.
[Graphical view ]
SMARTi SM00062. PBPb. 2 hits.
[Graphical view ]
SUPFAMi SSF161098. SSF161098. 1 hit.
TIGRFAMsi TIGR01726. HEQRo_perm_3TM. 1 hit.
PROSITEi PS50928. ABC_TM1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-334 / TIGR4.
  2. "Crystal structure of the second substrate binding domain of a putative amino acid ABC transporter from Streptococcus pneumoniae Canada MDR_19A."
    Stogios P.J., Wawrzak Z., Kudritska M., Yim V., Savchenko A., Anderson W.F.
    Submitted (JAN-2014) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) OF 266-487.

Entry informationi

Entry nameiQ97QH2_STRPN
AccessioniPrimary (citable) accession number: Q97QH2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2001
Last sequence update: October 1, 2001
Last modified: September 3, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

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