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Q97PV8

- Q97PV8_STRPN

UniProt

Q97PV8 - Q97PV8_STRPN

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Protein
Submitted name:

Oxidoreductase, Gfo/Idh/MocA family

Gene

SP_1482

Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei9 – 91NADPImported
Binding sitei121 – 1211NADPImported
Binding sitei164 – 1641NADPImported
Binding sitei181 – 1811NADPImported

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi33 – 342NADPImported
Nucleotide bindingi71 – 755NADPImported
Nucleotide bindingi92 – 932NADPImported

GO - Molecular functioni

  1. nucleotide binding Source: UniProtKB-KW
  2. oxidoreductase activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

NADPImported, Nucleotide-bindingImported

Enzyme and pathway databases

BioCyciSPNE170187:GHGN-1488-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Oxidoreductase, Gfo/Idh/MocA familyImported
Gene namesi
Ordered Locus Names:SP_1482Imported
OrganismiStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)Imported
Taxonomic identifieri170187 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000585: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi170187.SP_1482.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2HO5X-ray2.56A/B1-325[»]
4IQ0X-ray2.00A/B/C/D1-325[»]
4NHEX-ray1.95A/B/C1-325[»]
ProteinModelPortaliQ97PV8.
SMRiQ97PV8. Positions 1-322.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ97PV8.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000227441.
OMAiARNYHEE.
OrthoDBiEOG6GJBW3.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
[Graphical view]
PfamiPF01408. GFO_IDH_MocA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q97PV8 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLKLGVIGTG AISHHFIEAA HTSGEYQLVA IYSRKLETAA TFASRYQNIQ
60 70 80 90 100
LFDQLEVFFK SSFDLVYIAS PNSLHFAQAK AALSAGKHVI LEKPAVSQPQ
110 120 130 140 150
EWFDLIQTAE KNNCFIFEAA RNYHEKAFTT IKNFLADKQV LGADFNYAKY
160 170 180 190 200
SSKMPDLLAG QTPNVFSDRF AGGALMDLGI YPLYAAVRLF GKANDATYHA
210 220 230 240 250
QQLDNSIDLN GDGILFYPDY QVHIKAGKNI TSNLPCEIYT TDGTLTLNTI
260 270 280 290 300
EHIRSAIFTD HQGNQVQLPI QQAPHTMTEE VAAFAHMIQQ PDLNLYQTWL
310 320
YDAGSVHELL YTMRQTAGIR FEAEK
Length:325
Mass (Da):36,374
Last modified:October 1, 2001 - v1
Checksum:i78E2EADDFE781343
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005672 Genomic DNA. Translation: AAK75576.1.
PIRiG95172.
RefSeqiNP_345936.1. NC_003028.3.

Genome annotation databases

EnsemblBacteriaiAAK75576; AAK75576; SP_1482.
GeneIDi931358.
KEGGispn:SP_1482.
PATRICi19707383. VBIStrPne105772_1534.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005672 Genomic DNA. Translation: AAK75576.1 .
PIRi G95172.
RefSeqi NP_345936.1. NC_003028.3.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2HO5 X-ray 2.56 A/B 1-325 [» ]
4IQ0 X-ray 2.00 A/B/C/D 1-325 [» ]
4NHE X-ray 1.95 A/B/C 1-325 [» ]
ProteinModelPortali Q97PV8.
SMRi Q97PV8. Positions 1-322.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 170187.SP_1482.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK75576 ; AAK75576 ; SP_1482 .
GeneIDi 931358.
KEGGi spn:SP_1482.
PATRICi 19707383. VBIStrPne105772_1534.

Phylogenomic databases

HOGENOMi HOG000227441.
OMAi ARNYHEE.
OrthoDBi EOG6GJBW3.

Enzyme and pathway databases

BioCyci SPNE170187:GHGN-1488-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q97PV8.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR016040. NAD(P)-bd_dom.
IPR000683. Oxidoreductase_N.
[Graphical view ]
Pfami PF01408. GFO_IDH_MocA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-334 / TIGR4Imported.
  2. "Crystal structure of Oxidoreductase, Gfo/Idh/MocA family from Streptococcus pneumoniae."
    Chang C., Hatzos C., Abdullah J., Joachimiak A.
    Submitted (JUL-2006) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.56 ANGSTROMS).
  3. "Crystal structure of oxidoreductase, Gfo/Idh/MocA family from Streptococcus pneumoniae with reductive methylated Lysine."
    Chang C., Hatzos-Skintges C., Abdullah J., Joachimiak A.
    Submitted (JAN-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).
  4. "The crystal structure of oxidoreductase (Gfo/Idh/MocA family) from Streptococcus pneumoniae TIGR4 in complex with NADP."
    Tan K., Hatzos-Skintges C., Jedrzejczak R., Joachimiak A.
    Submitted (NOV-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) IN COMPLEX WITH NADP.

Entry informationi

Entry nameiQ97PV8_STRPN
AccessioniPrimary (citable) accession number: Q97PV8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2001
Last sequence update: October 1, 2001
Last modified: October 29, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteomeImported

External Data

Dasty 3