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Q97PV8

- Q97PV8_STRPN

UniProt

Q97PV8 - Q97PV8_STRPN

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Protein
Submitted name: Oxidoreductase, Gfo/Idh/MocA family
Gene
SP_1482
Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei9 – 91NADPImported
Binding sitei121 – 1211NADPImported
Binding sitei164 – 1641NADPImported
Binding sitei181 – 1811NADPImported

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi33 – 342NADPImported
Nucleotide bindingi71 – 755NADPImported
Nucleotide bindingi92 – 932NADPImported

GO - Molecular functioni

  1. nucleotide binding Source: UniProtKB-KW
  2. oxidoreductase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Ligandi

    NADPImported, Nucleotide-bindingImported

    Enzyme and pathway databases

    BioCyciSPNE170187:GHGN-1488-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Oxidoreductase, Gfo/Idh/MocA familyImported
    Gene namesi
    Ordered Locus Names:SP_1482Imported
    OrganismiStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)Imported
    Taxonomic identifieri170187 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000000585: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi170187.SP_1482.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2HO5X-ray2.56A/B1-325[»]
    4IQ0X-ray2.00A/B/C/D1-325[»]
    4NHEX-ray1.95A/B/C1-325[»]
    ProteinModelPortaliQ97PV8.
    SMRiQ97PV8. Positions 1-322.

    Miscellaneous databases

    EvolutionaryTraceiQ97PV8.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000227441.
    OMAiARNYHEE.
    OrthoDBiEOG6GJBW3.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR016040. NAD(P)-bd_dom.
    IPR000683. Oxidoreductase_N.
    [Graphical view]
    PfamiPF01408. GFO_IDH_MocA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q97PV8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLKLGVIGTG AISHHFIEAA HTSGEYQLVA IYSRKLETAA TFASRYQNIQ    50
    LFDQLEVFFK SSFDLVYIAS PNSLHFAQAK AALSAGKHVI LEKPAVSQPQ 100
    EWFDLIQTAE KNNCFIFEAA RNYHEKAFTT IKNFLADKQV LGADFNYAKY 150
    SSKMPDLLAG QTPNVFSDRF AGGALMDLGI YPLYAAVRLF GKANDATYHA 200
    QQLDNSIDLN GDGILFYPDY QVHIKAGKNI TSNLPCEIYT TDGTLTLNTI 250
    EHIRSAIFTD HQGNQVQLPI QQAPHTMTEE VAAFAHMIQQ PDLNLYQTWL 300
    YDAGSVHELL YTMRQTAGIR FEAEK 325
    Length:325
    Mass (Da):36,374
    Last modified:October 1, 2001 - v1
    Checksum:i78E2EADDFE781343
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005672 Genomic DNA. Translation: AAK75576.1.
    PIRiG95172.
    RefSeqiNP_345936.1. NC_003028.3.

    Genome annotation databases

    EnsemblBacteriaiAAK75576; AAK75576; SP_1482.
    GeneIDi931358.
    KEGGispn:SP_1482.
    PATRICi19707383. VBIStrPne105772_1534.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005672 Genomic DNA. Translation: AAK75576.1 .
    PIRi G95172.
    RefSeqi NP_345936.1. NC_003028.3.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2HO5 X-ray 2.56 A/B 1-325 [» ]
    4IQ0 X-ray 2.00 A/B/C/D 1-325 [» ]
    4NHE X-ray 1.95 A/B/C 1-325 [» ]
    ProteinModelPortali Q97PV8.
    SMRi Q97PV8. Positions 1-322.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 170187.SP_1482.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK75576 ; AAK75576 ; SP_1482 .
    GeneIDi 931358.
    KEGGi spn:SP_1482.
    PATRICi 19707383. VBIStrPne105772_1534.

    Phylogenomic databases

    HOGENOMi HOG000227441.
    OMAi ARNYHEE.
    OrthoDBi EOG6GJBW3.

    Enzyme and pathway databases

    BioCyci SPNE170187:GHGN-1488-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q97PV8.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR016040. NAD(P)-bd_dom.
    IPR000683. Oxidoreductase_N.
    [Graphical view ]
    Pfami PF01408. GFO_IDH_MocA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-334 / TIGR4.
    2. "Crystal structure of Oxidoreductase, Gfo/Idh/MocA family from Streptococcus pneumoniae."
      Chang C., Hatzos C., Abdullah J., Joachimiak A.
      Submitted (JUL-2006) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.56 ANGSTROMS).
    3. "Crystal structure of oxidoreductase, Gfo/Idh/MocA family from Streptococcus pneumoniae with reductive methylated Lysine."
      Chang C., Hatzos-Skintges C., Abdullah J., Joachimiak A.
      Submitted (JAN-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).
    4. "The crystal structure of oxidoreductase (Gfo/Idh/MocA family) from Streptococcus pneumoniae TIGR4 in complex with NADP."
      Tan K., Hatzos-Skintges C., Jedrzejczak R., Joachimiak A.
      Submitted (NOV-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) IN COMPLEX WITH NADP.

    Entry informationi

    Entry nameiQ97PV8_STRPN
    AccessioniPrimary (citable) accession number: Q97PV8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2001
    Last sequence update: October 1, 2001
    Last modified: June 11, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome

    External Data

    Dasty 3

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