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Protein

Cytidylate kinase

Gene

cmk

Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + (d)CMP = ADP + (d)CDP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 189ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSPNE170187:GHGN-1610-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytidylate kinaseUniRule annotation (EC:2.7.4.25UniRule annotation)
Short name:
CKUniRule annotation
Alternative name(s):
Cytidine monophosphate kinaseUniRule annotation
Short name:
CMP kinaseUniRule annotation
Gene namesi
Name:cmkUniRule annotation
Ordered Locus Names:SP_1603
OrganismiStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Taxonomic identifieri170187 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000585 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 223223Cytidylate kinasePRO_0000131985Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi170187.SpneT_02001681.

Structurei

Secondary structure

1
223
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi5 – 95Combined sources
Helixi16 – 2712Combined sources
Beta strandi30 – 334Combined sources
Helixi34 – 4714Combined sources
Helixi55 – 6410Combined sources
Beta strandi68 – 725Combined sources
Turni73 – 753Combined sources
Beta strandi76 – 816Combined sources
Beta strandi84 – 907Combined sources
Helixi93 – 10311Combined sources
Helixi106 – 12015Combined sources
Beta strandi125 – 1284Combined sources
Beta strandi133 – 1364Combined sources
Helixi137 – 1393Combined sources
Beta strandi141 – 1477Combined sources
Helixi150 – 16314Combined sources
Helixi170 – 18415Combined sources
Beta strandi188 – 1903Combined sources
Beta strandi199 – 2024Combined sources
Helixi208 – 22215Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1Q3TNMR-A1-223[»]
ProteinModelPortaliQ97PK6.
SMRiQ97PK6. Positions 1-223.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ97PK6.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytidylate kinase family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CAT. Bacteria.
COG0283. LUCA.
HOGENOMiHOG000242850.
KOiK00945.
OMAiVRARRRY.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00238. Cytidyl_kinase_type1. 1 hit.
InterProiIPR003136. Cytidylate_kin.
IPR011994. Cytidylate_kinase_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF02224. Cytidylate_kin. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00017. cmk. 1 hit.

Sequencei

Sequence statusi: Complete.

Q97PK6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTIQIAIDG PASSGKSTVA KIIAKDFGFT YLDTGAMYRA ATYMALKNQL
60 70 80 90 100
GVEEVEALLA LLDQHPISFG RSETGDQLVF VGDVDITHPI RENEVTNHVS
110 120 130 140 150
AIAAIPQVRE KLVSLQQEIA QQGGIVMDGR DIGTVVLPQA ELKIFLVASV
160 170 180 190 200
DERAERRYKE NIAKGIETDL ETLKKEIAAR DYKDSHRETS PLKQAEDAVY
210 220
LDTTGLNIQE VVEKIKAEAE KRM
Length:223
Mass (Da):24,597
Last modified:October 1, 2001 - v1
Checksum:iEDE12AD6B4D721DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005672 Genomic DNA. Translation: AAK75687.1.
PIRiF95186.
RefSeqiWP_000849381.1. NZ_AKVY01000001.1.

Genome annotation databases

EnsemblBacteriaiAAK75687; AAK75687; SP_1603.
KEGGispn:SP_1603.
PATRICi19707633. VBIStrPne105772_1658.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005672 Genomic DNA. Translation: AAK75687.1.
PIRiF95186.
RefSeqiWP_000849381.1. NZ_AKVY01000001.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1Q3TNMR-A1-223[»]
ProteinModelPortaliQ97PK6.
SMRiQ97PK6. Positions 1-223.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi170187.SpneT_02001681.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK75687; AAK75687; SP_1603.
KEGGispn:SP_1603.
PATRICi19707633. VBIStrPne105772_1658.

Phylogenomic databases

eggNOGiENOG4105CAT. Bacteria.
COG0283. LUCA.
HOGENOMiHOG000242850.
KOiK00945.
OMAiVRARRRY.

Enzyme and pathway databases

BioCyciSPNE170187:GHGN-1610-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ97PK6.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00238. Cytidyl_kinase_type1. 1 hit.
InterProiIPR003136. Cytidylate_kin.
IPR011994. Cytidylate_kinase_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF02224. Cytidylate_kin. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00017. cmk. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiKCY_STRPN
AccessioniPrimary (citable) accession number: Q97PK6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 26, 2002
Last sequence update: October 1, 2001
Last modified: September 7, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.