Reviewed, UniProtKB/Swiss-Prot Q97P15 (GALT1_STRPN)

Names and origin

Protein names

Recommended name:
    Galactose-1-phosphate uridylyltransferase 1
      Short name=Gal-1-P uridylyltransferase 1
    EC=2.7.7.12
Alternative name(s):
    UDP-glucose--hexose-1-phosphate uridylyltransferase 1

Gene names

Name:	galT1
Ordered Locus Names:	SP_1829

Organism

Streptococcus pneumoniae [Complete proteome] [HAMAP]

Taxonomic identifier

1313 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	491 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 491	491	Galactose-1-phosphate uridylyltransferase 1 HAMAP MF_00571		PRO_0000169914

Sequences

	Sequence		Length	Mass (Da)
	Q97P15-1 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: A11F78D61F4D4B09	FASTA	491	56,381
	10 20 30 40 50 60 MKTIIDNFVD RVIEYGMYNE IDKIYVKNRV LALIGEEGID RISDENDLKQ IKDYLVEIAL 70 80 90 100 110 120 KNGKIKDLIE EKECLGAELM NFIVPLPSRL NDIFWSSYDI SPQEAVEEFY KLSKDSDYIK 130 140 150 160 170 180 TSAIAKNIEF RASTKYGELE ITINLSKPEK DPKTIAAEKL VKATNYPKCL LCMENEGYQG 190 200 210 220 230 240 RINYPARSNH RIIRLKLGDE VWGFQYSPYS YFNEHAIFLN SQHVPMAITS KTFEQLLEIV 250 260 270 280 290 300 DILPGYFAGS NSDLPISGGS ILSHNHYQGG KHIFPMEKAK FESEFCFKDF EDVNAGIVKW 310 320 330 340 350 360 PMSVIRLQSE NKNRLLDLAT KILNKWREYS DLEVDIIAMT EDVPHHTVTP IARKVDGRYE 370 380 390 400 410 420 LDIVLRDNHT TEQYPDGVFH PHQDVQHIKK ENIGLIEVMG LAILPPRLKP ELEEVGKYLL 430 440 450 460 470 480 GEDNAIADYH LEWADQLKEK YPRINKEEVN SVVQHEAGQV FARVLEDAGV YKNTPSGHEA 490 FMRFVKSVGI N

References

[1]

"Complete genome sequence of a virulent isolate of Streptococcus pneumoniae." Tettelin H., Nelson K.E., Paulsen I.T., Eisen J.A., Read T.D., Peterson S.N., Heidelberg J.F., DeBoy R.T., Haft D.H., Dodson R.J., Durkin A.S., Gwinn M.L., Kolonay J.F., Nelson W.C., Peterson J.D., Umayam L.A., White O., Salzberg S.L. , Lewis M.R., Radune D., Holtzapple E.K., Khouri H.M., Wolf A.M., Utterback T.R., Hansen C.L., McDonald L.A., Feldblyum T.V., Angiuoli S.V., Dickinson T., Hickey E.K., Holt I.E., Loftus B.J., Yang F., Smith H.O., Venter J.C., Dougherty B.A., Morrison D.A., Hollingshead S.K., Fraser C.M. Science 293:498-506(2001) [PubMed: 11463916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-334 / TIGR4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE005672 Genomic DNA. Translation: AAK75902.1.
PIR	E95213.
RefSeq	NP_346262.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	931006.
GenomeReviews	Gene locus SP_1829 in contig AE005672_GR.
KEGG	spn:SP_1829.
TIGR	SP_1829.
Phylogenomic databases
HOGENOM	Q97P15.
OMA	LEMSESM.
Enzyme and pathway databases
BRENDA	2.7.7.12. 600.
Family and domain databases
HAMAP	MF_00571. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
TIGRFAMs	TIGR01239. galT_2. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT1_STRPN

Accession

Primary (citable) accession number: Q97P15

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 26, 2002
Last sequence update:	October 1, 2001
Last modified:	November 3, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)