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Q97NG0

- G6PI_STRPN

UniProt

Q97NG0 - G6PI_STRPN

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 Oct 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei291 – 2911Proton donorBy similarity
    Active sitei312 – 3121By similarity
    Active sitei426 – 4261By similarity

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciSPNE170187:GHGN-2131-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomerase (EC:5.3.1.9)
    Short name:
    GPI
    Alternative name(s):
    Phosphoglucose isomerase
    Short name:
    PGI
    Phosphohexose isomerase
    Short name:
    PHI
    Gene namesi
    Name:pgi
    Ordered Locus Names:SP_2070
    OrganismiStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
    Taxonomic identifieri170187 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000000585: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 449449Glucose-6-phosphate isomerasePRO_0000180738Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi170187.SP_2070.

    Structurei

    3D structure databases

    ProteinModelPortaliQ97NG0.
    SMRiQ97NG0. Positions 3-449.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.Curated

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100403.
    KOiK01810.
    OMAiKNMTHIT.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q97NG0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSHIKFDYSK VLDKFVAPHE VEYMQSQVTA ADELIRKGTG AGSDFLGWLD    50
    LPEKYDREEF DRILKAAEQI KSDSDVLVVI GIGGSYLGAK AAIDFLNHHF 100
    ANLQTKEERK APQILYAGNS ISSTYLADLV EYVADKDFSV NVISKSGTTT 150
    EPAIAFRVFK ELLVKKYGQE EANKRIYATT DRQKGAVKVE ADANGWGTFV 200
    VPDDIGGRFS VLTAVGLLSI AASGADIKAL MEGANAARKD YTSDKISENE 250
    AYQYAAVRNI LYRKGYATEI LVNYEPSLQY FSEWWKQLAG ESEGKDQKGI 300
    YPTSANFSTD LHSLGQFIQE GTRIMFETVV RVDKPRKNVL IPTLEEDLDG 350
    LGYLQGKDVD FVNKKATDGV LLAHTDGDVP NMYVTLPEQD AFTLGYTIYF 400
    FELAIALSGY LNAINPFDQP GVEAYKRNMF ALLGKPGFEE LSKELNARL 449
    Length:449
    Mass (Da):49,868
    Last modified:October 1, 2001 - v1
    Checksum:i625B5FF420079C2B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005672 Genomic DNA. Translation: AAK76133.1.
    PIRiD95242.
    RefSeqiNP_346493.1. NC_003028.3.
    WP_000018264.1. NZ_AKVY01000001.1.

    Genome annotation databases

    EnsemblBacteriaiAAK76133; AAK76133; SP_2070.
    GeneIDi930266.
    KEGGispn:SP_2070.
    PATRICi19708725. VBIStrPne105772_2153.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005672 Genomic DNA. Translation: AAK76133.1 .
    PIRi D95242.
    RefSeqi NP_346493.1. NC_003028.3.
    WP_000018264.1. NZ_AKVY01000001.1.

    3D structure databases

    ProteinModelPortali Q97NG0.
    SMRi Q97NG0. Positions 3-449.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 170187.SP_2070.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK76133 ; AAK76133 ; SP_2070 .
    GeneIDi 930266.
    KEGGi spn:SP_2070.
    PATRICi 19708725. VBIStrPne105772_2153.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100403.
    KOi K01810.
    OMAi KNMTHIT.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci SPNE170187:GHGN-2131-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-334 / TIGR4.

    Entry informationi

    Entry nameiG6PI_STRPN
    AccessioniPrimary (citable) accession number: Q97NG0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 2, 2001
    Last sequence update: October 1, 2001
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3