SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q97N97

- FUCI_STRPN

UniProt

Q97N97 - FUCI_STRPN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
L-fucose isomerase
Gene
fucI, SP_2158
Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Converts the aldose L-fucose into the corresponding ketose L-fuculose By similarity.UniRule annotation

Catalytic activityi

L-fucopyranose = L-fuculose.UniRule annotation

Cofactori

Manganese By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei335 – 3351Proton acceptor By similarity
Metal bindingi335 – 3351Manganese By similarity
Active sitei359 – 3591Proton acceptor By similarity
Metal bindingi359 – 3591Manganese By similarity
Metal bindingi525 – 5251Manganese By similarity

GO - Molecular functioni

  1. L-fucose isomerase activity Source: UniProtKB-HAMAP
  2. manganese ion binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. L-fucose catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism, Fucose metabolism

Keywords - Ligandi

Manganese, Metal-binding

Enzyme and pathway databases

BioCyciSPNE170187:GHGN-2218-MONOMER.
UniPathwayiUPA00563; UER00624.

Names & Taxonomyi

Protein namesi
Recommended name:
L-fucose isomerase (EC:5.3.1.25)
Alternative name(s):
6-deoxy-L-galactose isomerase
FucIase
Gene namesi
Name:fucI
Ordered Locus Names:SP_2158
OrganismiStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Taxonomic identifieri170187 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000585: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 588588L-fucose isomeraseUniRule annotation
PRO_0000204152Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi170187.SP_2158.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi6 – 127
Turni17 – 193
Helixi20 – 4223
Beta strandi53 – 553
Beta strandi60 – 623
Helixi63 – 7412
Turni75 – 773
Beta strandi78 – 8710
Helixi91 – 944
Beta strandi99 – 1013
Beta strandi103 – 1075
Beta strandi111 – 1133
Helixi115 – 12915
Beta strandi134 – 1363
Helixi151 – 17020
Beta strandi174 – 1807
Helixi186 – 1883
Helixi192 – 1998
Beta strandi202 – 2065
Helixi209 – 2168
Helixi222 – 23514
Helixi245 – 2473
Helixi251 – 27323
Helixi276 – 2805
Helixi286 – 2883
Beta strandi292 – 2976
Turni300 – 3067
Helixi311 – 3188
Beta strandi319 – 3224
Beta strandi331 – 3344
Helixi338 – 35114
Beta strandi356 – 3649
Helixi366 – 3738
Helixi379 – 3813
Beta strandi385 – 3884
Helixi396 – 3994
Beta strandi402 – 4043
Beta strandi407 – 4093
Helixi413 – 4153
Helixi418 – 4269
Turni435 – 4373
Beta strandi454 – 46310
Turni464 – 4663
Beta strandi467 – 47711
Helixi482 – 4909
Beta strandi498 – 5036
Helixi514 – 5196
Beta strandi523 – 5319
Helixi534 – 54411
Beta strandi548 – 5503
Helixi555 – 5573
Helixi562 – 5676
Helixi572 – 58312

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4C20X-ray2.41A/B2-588[»]
4C21X-ray2.55A/B1-588[»]
4C22X-ray2.70A/B2-588[»]
ProteinModelPortaliQ97N97.
SMRiQ97N97. Positions 2-588.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2407.
HOGENOMiHOG000249674.
KOiK01818.
OMAiKEGQDYR.
OrthoDBiEOG6FJNCF.

Family and domain databases

Gene3Di3.20.14.10. 1 hit.
3.40.275.10. 1 hit.
3.40.50.1070. 1 hit.
HAMAPiMF_01254. Fucose_iso.
InterProiIPR004216. Fuc/Ara_isomerase_C.
IPR015888. Fuc_isomerase_C.
IPR012888. Fucose_iso_N1.
IPR005763. Fucose_isomerase.
IPR009015. Fucose_isomerase_N/cen.
IPR012889. Fucose_isomerase_N2.
[Graphical view]
PfamiPF02952. Fucose_iso_C. 1 hit.
PF07881. Fucose_iso_N1. 1 hit.
PF07882. Fucose_iso_N2. 1 hit.
[Graphical view]
SUPFAMiSSF50443. SSF50443. 1 hit.
SSF53743. SSF53743. 1 hit.
TIGRFAMsiTIGR01089. fucI. 1 hit.

Sequencei

Sequence statusi: Complete.

Q97N97-1 [UniParc]FASTAAdd to Basket

« Hide

MIQHPRIGIR PTIDGRRQGV RESLEVQTMN MAKSVADLIS STLKYPDGEP    50
VECVISPSTI GRVPEAAASH ELFKKSNVCA TITVTPCWCY GSETMDMSPD 100
IPHAIWGFNG TERPGAVYLA AVLASHAQKG IPAFGIYGRD VQEASDTDIP 150
EDVKEKLLRY ARAALATGLM RDTAYLSMGS VSMGIGGSIV NPDFFQEYLG 200
MRNESVDMTE FTRRMDRGIY DPEEFERALK WVKENVKEGF DHNREDLVLS 250
REEKDRQWEF VIKMFMIGRD LMVGNPRLAE LGFEEEAVGH HALVAGFQGQ 300
RQWTDHFPNG DFMETFLNTQ FDWNGIRKPF VFATENDSLN GVSMLFNYLL 350
TNTPQIFADV RTYWSPEAVK RVTGHTLEGR AAAGFLHLIN SGSCTLDGTG 400
QATRDGKPIM KPFWELEESE VQAMLENTDF PPANREYFRG GGFSTRFLTK 450
GDMPVTMVRL NLLKGVGPVL QIAEGYTLEL PEDVHHTLDN RTDPGWPTTW 500
FAPRLTGKGA FKSVYDVMNN WGANHGAITY GHIGADLITL ASMLRIPVNM 550
HNVPEEDIFR PKNWSLFGTE DLESADYRAC QLLGPLHK 588
Length:588
Mass (Da):65,895
Last modified:October 1, 2001 - v1
Checksum:i06E678EDF801786A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005672 Genomic DNA. Translation: AAK76212.1.
PIRiC95252.
RefSeqiNP_346572.1. NC_003028.3.

Genome annotation databases

EnsemblBacteriaiAAK76212; AAK76212; SP_2158.
GeneIDi930204.
KEGGispn:SP_2158.
PATRICi19708921. VBIStrPne105772_2252.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE005672 Genomic DNA. Translation: AAK76212.1 .
PIRi C95252.
RefSeqi NP_346572.1. NC_003028.3.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4C20 X-ray 2.41 A/B 2-588 [» ]
4C21 X-ray 2.55 A/B 1-588 [» ]
4C22 X-ray 2.70 A/B 2-588 [» ]
ProteinModelPortali Q97N97.
SMRi Q97N97. Positions 2-588.
ModBasei Search...

Protein-protein interaction databases

STRINGi 170187.SP_2158.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK76212 ; AAK76212 ; SP_2158 .
GeneIDi 930204.
KEGGi spn:SP_2158.
PATRICi 19708921. VBIStrPne105772_2252.

Phylogenomic databases

eggNOGi COG2407.
HOGENOMi HOG000249674.
KOi K01818.
OMAi KEGQDYR.
OrthoDBi EOG6FJNCF.

Enzyme and pathway databases

UniPathwayi UPA00563 ; UER00624 .
BioCyci SPNE170187:GHGN-2218-MONOMER.

Family and domain databases

Gene3Di 3.20.14.10. 1 hit.
3.40.275.10. 1 hit.
3.40.50.1070. 1 hit.
HAMAPi MF_01254. Fucose_iso.
InterProi IPR004216. Fuc/Ara_isomerase_C.
IPR015888. Fuc_isomerase_C.
IPR012888. Fucose_iso_N1.
IPR005763. Fucose_isomerase.
IPR009015. Fucose_isomerase_N/cen.
IPR012889. Fucose_isomerase_N2.
[Graphical view ]
Pfami PF02952. Fucose_iso_C. 1 hit.
PF07881. Fucose_iso_N1. 1 hit.
PF07882. Fucose_iso_N2. 1 hit.
[Graphical view ]
SUPFAMi SSF50443. SSF50443. 1 hit.
SSF53743. SSF53743. 1 hit.
TIGRFAMsi TIGR01089. fucI. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-334 / TIGR4.

Entry informationi

Entry nameiFUCI_STRPN
AccessioniPrimary (citable) accession number: Q97N97
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: October 1, 2001
Last modified: May 14, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi