Q97N13 (DCD_CLOAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	CA_C0025

Organism

Clostridium acetobutylicum

Taxonomic identifier

1488 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	173 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 173	173	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_0000155979

Sequences

	Sequence		Length	Mass (Da)
	Q97N13 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 97393788C854FD65	FASTA	173	19,909
	10 20 30 40 50 60 MILSGKQIKD SLGKDIVIEP FNEKQINPNS YNLKLHNELL VYDEEVLDMK KPNKTKKLII 70 80 90 100 110 120 PEEGIVLEPR KLYLGRTLEY TETDKYVPML EGRSSIGRLG VFIHVTAGFG DVGFKGYWTL 130 140 150 160 170 EIFCVEPIRI YSGVEICQIY YHDVGGDYEK YSSGKYQNNK GIQPSLLYKD FIN

References

[1]

"Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum." Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R., Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F., Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V., Smith D.R. J. Bacteriol. 183:4823-4838(2001) [PubMed: 11466286] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001437 Genomic DNA. Translation: AAK78012.1.
PIR	A96903.
RefSeq	NP_346672.1. NC_003030.1.
3D structure databases
ProteinModelPortal	Q97N13.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1116208.
GenomeReviews	Gene locus CA_C0025 in contig AE001437_GR.
KEGG	cac:CA_C0025.
NMPDR	fig|272562.1.peg.201.
PATRIC	32034309. VBICloAce74127_0204.
Phylogenomic databases
HOGENOM	HBG553199.
OMA	HQTAGWI.
PhylomeDB	Q97N13.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	CACE272562:CAC0025-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
KO	K01494.
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CLOAB

Accession

Primary (citable) accession number: Q97N13

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 27, 2002
Last sequence update:	October 1, 2001
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program