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Reviewed, UniProtKB/Swiss-Prot Q97N08 (PSD1_CLOAB)

Last modified November 3, 2009. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Phosphatidylserine decarboxylase proenzyme 1
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain 1
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain 1
Gene names
Name: psd1
Ordered Locus Names: CA_C0031
OrganismClostridium acetobutylicum [Complete proteome] [HAMAP]
Taxonomic identifier1488 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

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Protein attributes

Sequence length294 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00663

Cofactor

Pyruvoyl group By similarity.

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00663

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 2 subfamily.

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Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 255255Phosphatidylserine decarboxylase beta chain 1 By similarity
PRO_0000029735
Chain256 – 29439Phosphatidylserine decarboxylase alpha chain 1 By similarity
PRO_0000029736

Sites

Site255 – 2562Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2561Pyruvic acid (Ser) By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q97N08-1 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: 90F8AB6316B17575

FASTA29433,792
        10         20         30         40         50         60 
MIKYYNRKTK QYEIEKVAGE NYLNWTYSSP IGMSFLEALI KKKAFSSIYG SFCDSKISKG 

        70         80         90        100        110        120 
KVKKFIDSFD IDILESEKKP EAFKSFNDFF TRKLTKEARP FSTNKEILIS PGDGRLLVYE 

       130        140        150        160        170        180 
NIDLDNLVEI KGMGYSLKEL IKDEKISSKY KNGICMILRL CPTDYHRFHF VDSGVCSATS 

       190        200        210        220        230        240 
KIKGSYYSVN PIALNKVKRL FCENKREWSI LKSDNFKDIL YIEVGATCVG SIIQTYKENT 

       250        260        270        280        290 
KVNKGDEKGY FKFGGSTVVL FFEKDSVKID EDILEQTRLG YETKVFMGES IGKK

« Hide

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References

[1]"Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum."
Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R., Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F., Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V., Smith D.R.
J. Bacteriol. 183:4823-4838(2001) [PubMed: 11466286] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

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Cross-references

Sequence databases

AE001437 Genomic DNA. Translation: AAK78018.1.
PIRG96903.
RefSeqNP_346678.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1116214.
GenomeReviewsGene locus CA_C0031 in contig AE001437_GR.
KEGGcac:CAC0031.
NMPDRfig|272562.1.peg.207.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ97N08.
OMAINQDEME.

Enzyme and pathway databases

BioCycCACE272562:CAC0031-MON.
BRENDA4.1.1.65. 2866.

Family and domain databases

HAMAPMF_00663.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

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Entry information

Entry namePSD1_CLOAB
AccessionPrimary (citable) accession number: Q97N08
Entry history
Integrated into UniProtKB/Swiss-Prot: July 3, 2003
Last sequence update: October 1, 2001
Last modified: November 3, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents