ID   Q97LW1_CLOAB            Unreviewed;       569 AA.
AC   Q97LW1;
DT   01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2001, sequence version 1.
DT   27-MAR-2024, entry version 108.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:AAK78423.1};
GN   OrderedLocusNames=CA_C0443 {ECO:0000313|EMBL:AAK78423.1};
OS   Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS   / VKM B-1787).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=272562 {ECO:0000313|EMBL:AAK78423.1, ECO:0000313|Proteomes:UP000000814};
RN   [1] {ECO:0000313|EMBL:AAK78423.1, ECO:0000313|Proteomes:UP000000814}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787
RC   {ECO:0000313|Proteomes:UP000000814};
RX   PubMed=11466286; DOI=10.1128/JB.183.16.4823-4838.2001;
RA   Nolling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA   Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA   Doucette-Stamm L., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA   Smith D.R.;
RT   "Genome sequence and comparative analysis of the solvent-producing
RT   bacterium Clostridium acetobutylicum.";
RL   J. Bacteriol. 183:4823-4838(2001).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE001437; AAK78423.1; -; Genomic_DNA.
DR   PIR; D96954; D96954.
DR   RefSeq; NP_347083.1; NC_003030.1.
DR   RefSeq; WP_010963765.1; NC_003030.1.
DR   AlphaFoldDB; Q97LW1; -.
DR   STRING; 272562.CA_C0443; -.
DR   GeneID; 44996952; -.
DR   KEGG; cac:CA_C0443; -.
DR   PATRIC; fig|272562.8.peg.641; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_9; -.
DR   OrthoDB; 369336at2; -.
DR   Proteomes; UP000000814; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR024478; HlyB_4HB_MCP.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF12729; 4HB_MCP_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000814};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        189..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          211..263
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          282..539
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   569 AA;  61383 MW;  867DA9F4836404A8 CRC64;
     MGKKGFKNLK VSSGIIILFV LAVFSSVLIG AVGYLKLKNV NENMHAMQNI QLQGVSRVGE
     AYGSVGVIRN NLTKLTDRKF DTKYIKDIDA TEVIINKNIR EEISALKDDS EGSKKAENLM
     NTFSDYMSFY DKLKTMRVAG ENPNQEFIDA NTKSGNNLQN AIKELSQYHK DQAQIITEKS
     NADFRDASIM LFLITAFIVV VGSVLSMIIL ISIKASINEF TTVINEVSHG DFSVQINTEG
     TNEFAILNKA LHKTIESIST IMRGVKDNAK DVSNQSVSLS AVSEEMSATS QEVSSTIGEV
     ADGSVSQAGE LVNMTAGINK FGEEIDRIVK NIKDVNTTAK QVSSMANVSN GQLQDLVSSV
     ENMNGSFESV VEKINKLVLS VNQINDITSL INSIADQTNL LALNAAIEAS RAGEAGKGFA
     VVADEIRTLA EQSKDSSSKI VTLVEDINKE TKSVLATTSD VNGTLSSQVT VIDTSISSFK
     EIIDEIEKII PEINDVSESM ESVTKQKSSI IEKAEGASAI AEENSASSEE ISASIEQMSA
     SSVEVANAAE KLSESANVMV GLVEQFKLK
//