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Q97L67

- UXAB_CLOAB

UniProt

Q97L67 - UXAB_CLOAB

Protein

Altronate oxidoreductase

Gene

uxaB

Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Oct 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi18 – 2912NADUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. coenzyme binding Source: InterPro
    2. tagaturonate reductase activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciCACE272562:GJIH-738-MONOMER.
    UniPathwayiUPA00246.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Altronate oxidoreductaseUniRule annotation (EC:1.1.1.58UniRule annotation)
    Alternative name(s):
    Tagaturonate dehydrogenaseUniRule annotation
    Tagaturonate reductaseUniRule annotation
    Gene namesi
    Name:uxaBUniRule annotation
    Ordered Locus Names:CA_C0695
    OrganismiClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
    Taxonomic identifieri272562 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000000814: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 482482Altronate oxidoreductasePRO_0000170741Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272562.CA_C0695.

    Structurei

    3D structure databases

    ProteinModelPortaliQ97L67.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the mannitol dehydrogenase family. UxaB subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0246.
    HOGENOMiHOG000029586.
    KOiK00041.
    OMAiSKFKVRV.
    OrthoDBiEOG6CVVB8.

    Family and domain databases

    Gene3Di1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    HAMAPiMF_00670. Altron_oxidoreduct.
    InterProiIPR008927. 6-PGluconate_DH_C-like.
    IPR023668. Altronate_OxRdtase.
    IPR013328. DH_multihelical.
    IPR000669. Mannitol_DH.
    IPR013118. Mannitol_DH_C.
    IPR013131. Mannitol_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF01232. Mannitol_dh. 1 hit.
    PF08125. Mannitol_dh_C. 1 hit.
    [Graphical view]
    PRINTSiPR00084. MTLDHDRGNASE.
    SUPFAMiSSF48179. SSF48179. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q97L67-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLNRSNFSE FKKYPEKILQ FGEGNFLRAF VDWQVDRMNK AADFNAGVVI    50
    VQPLEQGLVD MLNEQDGLYT LYLQGLKEGK AVKEHSVIDC VTRGLNPYTQ 100
    YEEYLKLAEN PEMEIVISNT TEAGIAFDEN DKLGRTCQNS YPGKLTAFLY 150
    RRFKTFNGDK SKGMLIIPCE LIDRNGEKLK ATILKFAELW NLEKEFADWI 200
    EEANTFCCTL VDRIVPGYPR DTIEEVHAEL GYEDSLVDVG EQFHLWVIEG 250
    PEWIKDILPF EKAGVNIQVV KDVTPYRTRK VRILNGAHTA LVPVAYLYGL 300
    DTVGHSVEDK VIGKYLTELV YDEIIPTLDL PEEELKYFAG AVLERFLNPF 350
    VNHYLMSIAL NSMPKFETRD LPSLLEYKKR KGQLPKKLVF SLAALIEFYK 400
    GKRGDEDIKL ADGEDILELY KDLWSKFDGT DACYRNIVET VLGYEKNWKM 450
    NLNELEGLTD AVTENLIKID KLGMKEAVKS VM 482
    Length:482
    Mass (Da):55,250
    Last modified:October 1, 2001 - v1
    Checksum:iA569F3B18D0919CA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001437 Genomic DNA. Translation: AAK78672.1.
    PIRiE96985.
    RefSeqiNP_347332.1. NC_003030.1.

    Genome annotation databases

    EnsemblBacteriaiAAK78672; AAK78672; CA_C0695.
    GeneIDi1116878.
    KEGGicac:CA_C0695.
    PATRICi32035757. VBICloAce74127_0898.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001437 Genomic DNA. Translation: AAK78672.1 .
    PIRi E96985.
    RefSeqi NP_347332.1. NC_003030.1.

    3D structure databases

    ProteinModelPortali Q97L67.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272562.CA_C0695.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK78672 ; AAK78672 ; CA_C0695 .
    GeneIDi 1116878.
    KEGGi cac:CA_C0695.
    PATRICi 32035757. VBICloAce74127_0898.

    Phylogenomic databases

    eggNOGi COG0246.
    HOGENOMi HOG000029586.
    KOi K00041.
    OMAi SKFKVRV.
    OrthoDBi EOG6CVVB8.

    Enzyme and pathway databases

    UniPathwayi UPA00246 .
    BioCyci CACE272562:GJIH-738-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    HAMAPi MF_00670. Altron_oxidoreduct.
    InterProi IPR008927. 6-PGluconate_DH_C-like.
    IPR023668. Altronate_OxRdtase.
    IPR013328. DH_multihelical.
    IPR000669. Mannitol_DH.
    IPR013118. Mannitol_DH_C.
    IPR013131. Mannitol_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF01232. Mannitol_dh. 1 hit.
    PF08125. Mannitol_dh_C. 1 hit.
    [Graphical view ]
    PRINTSi PR00084. MTLDHDRGNASE.
    SUPFAMi SSF48179. SSF48179. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

    Entry informationi

    Entry nameiUXAB_CLOAB
    AccessioniPrimary (citable) accession number: Q97L67
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 11, 2003
    Last sequence update: October 1, 2001
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3