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Protein

Adenine deaminase

Gene

ade

Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:CA_C0887
OrganismiClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Taxonomic identifieri272562 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000000814 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001424121 – 570Adenine deaminaseAdd BLAST570

Interactioni

Protein-protein interaction databases

STRINGi272562.CA_C0887.

Structurei

3D structure databases

ProteinModelPortaliQ97KN0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiRASTEMG.

Family and domain databases

CDDicd01295. AdeC. 1 hit.
Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

Q97KN0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYCIEEKIEK ALGIKEASLV LKNCNIVNVF SSEIIRGDLA IDGDTIIGIG
60 70 80 90 100
KYKGKTEIDL SNKYVAPGFI DSHVHIESSM VSPKEFARAV ISRGTTTIIV
110 120 130 140 150
DPHEIANVCG MDGIKYMMEE TKNMPLDVFF MLSSCVPATS FETSGAVLKA
160 170 180 190 200
EDLKELIDSD RVLGLGEMMN YPGVLSREEE VLNKLKLAGS YNKIVDGHAP
210 220 230 240 250
SVRGNELNAY NLAGIKTDHE CSSIEEMNEK IRNGMYIAIR EGSAAKNLDI
260 270 280 290 300
LIKGVNAKNE RRIMFCADDR HPDDILKSGH MDNCVRRAIY NGIENTAAIR
310 320 330 340 350
MASINAAECY KLERVGAIAP SYKADLVVLE DLKDVKVNMV IKSGEVVFKD
360 370 380 390 400
NKHLKDMGSK SDITKVSNTV NIKKVSEENL ELKLDTDVCS IISVALNSIS
410 420 430 440 450
TKNVKRKVNL SNGIFKCELN YGINKVAVIE RHKKSGSIGI GLVENFGLKR
460 470 480 490 500
GAIASTVAHD SHNIIVLGNN DEDMVKAVNE IERVGGGITI SLDGKIIETL
510 520 530 540 550
ELEIAGLMSN KSMEFVAERV SKMINICHNT LGVNKDIQPF MTLAFLALPV
560 570
IPEIRITDKG VFDVVNFKFL
Length:570
Mass (Da):62,622
Last modified:October 1, 2001 - v1
Checksum:iB0E95F3EC03ECCD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001437 Genomic DNA. Translation: AAK78863.1.
PIRiD97009.
RefSeqiNP_347523.1. NC_003030.1.
WP_010964205.1. NC_003030.1.

Genome annotation databases

EnsemblBacteriaiAAK78863; AAK78863; CA_C0887.
GeneIDi1117070.
KEGGicac:CA_C0887.
PATRICi32036155. VBICloAce74127_1097.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001437 Genomic DNA. Translation: AAK78863.1.
PIRiD97009.
RefSeqiNP_347523.1. NC_003030.1.
WP_010964205.1. NC_003030.1.

3D structure databases

ProteinModelPortaliQ97KN0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272562.CA_C0887.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK78863; AAK78863; CA_C0887.
GeneIDi1117070.
KEGGicac:CA_C0887.
PATRICi32036155. VBICloAce74127_1097.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiRASTEMG.

Family and domain databases

CDDicd01295. AdeC. 1 hit.
Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiADEC_CLOAB
AccessioniPrimary (citable) accession number: Q97KN0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: October 1, 2001
Last modified: November 2, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.