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Q97J51

- Y1435_CLOAB

UniProt

Q97J51 - Y1435_CLOAB

Protein

Uncharacterized RNA methyltransferase CA_C1435

Gene

CA_C1435

Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (01 Oct 2001)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi74 – 741Iron-sulfur (4Fe-4S)By similarity
    Metal bindingi80 – 801Iron-sulfur (4Fe-4S)By similarity
    Metal bindingi83 – 831Iron-sulfur (4Fe-4S)By similarity
    Metal bindingi163 – 1631Iron-sulfur (4Fe-4S)By similarity
    Binding sitei289 – 2891S-adenosyl-L-methioninePROSITE-ProRule annotation
    Binding sitei318 – 3181S-adenosyl-L-methionine; via carbonyl oxygenPROSITE-ProRule annotation
    Binding sitei339 – 3391S-adenosyl-L-methioninePROSITE-ProRule annotation
    Binding sitei384 – 3841S-adenosyl-L-methioninePROSITE-ProRule annotation
    Active sitei411 – 4111NucleophilePROSITE-ProRule annotation

    GO - Molecular functioni

    1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. RNA binding Source: InterPro
    4. RNA methyltransferase activity Source: InterPro

    GO - Biological processi

    1. RNA processing Source: InterPro

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Ligandi

    4Fe-4S, Iron, Iron-sulfur, Metal-binding, S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciCACE272562:GJIH-1484-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized RNA methyltransferase CA_C1435 (EC:2.1.1.-)
    Gene namesi
    Ordered Locus Names:CA_C1435
    OrganismiClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
    Taxonomic identifieri272562 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000000814: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 456456Uncharacterized RNA methyltransferase CA_C1435PRO_0000161969Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272562.CA_C1435.

    Structurei

    3D structure databases

    ProteinModelPortaliQ97J51.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini3 – 6159TRAMPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.PROSITE-ProRule annotation
    Contains 1 TRAM domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG2265.
    HOGENOMiHOG000029870.
    KOiK00599.
    OMAiCGGCTYQ.
    OrthoDBiEOG6V4GKM.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    3.40.50.150. 1 hit.
    InterProiIPR001566. 23S_rRNA_MeTrfase_RlmD.
    IPR012340. NA-bd_OB-fold.
    IPR029063. SAM-dependent_MTases-like.
    IPR002792. TRAM_dom.
    IPR010280. U5_MeTrfase_fam.
    [Graphical view]
    PfamiPF05958. tRNA_U5-meth_tr. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    SSF53335. SSF53335. 1 hit.
    TIGRFAMsiTIGR00479. rumA. 1 hit.
    PROSITEiPS51687. SAM_MT_RNA_M5U. 1 hit.
    PS50926. TRAM. 1 hit.
    PS01230. TRMA_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q97J51-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLMRKNETR EFLIEDIEFP AVGVAFYNDK KVYIKGAVPG QKVLARVSKV    50
    RREKIEAKLK EIVTNIPGAA QPKCPDFGVC GGCVHQFLPY EKQLEFKERE 100
    VLKLFKDAKI EGFEYLGILG SPEKEEYRNK MEYTFGDFVK GGELTLGMHA 150
    KNSGFSIVNT DKCNIVDEDF RIILKTVVEY FRKKDLPIYK VMQHVGYLRN 200
    LVVRKAKNTG EILIALVTTS QVDFDLTELT EILKSINYLG ELKGILHVIN 250
    DGLADMVRGD KIVTLFGQDY ITERILDLKF KISLFSFFQT NSKGAEKLYS 300
    EVLEFLGDVS NKTVFDLYCG TGTIGQLASK KAEKVIGIEL IEEAVEAAKE 350
    NTKLNNISNC SFIAGDVAKV ITEIKEKPDT IILDPPRPGV SPNAMKYVIK 400
    FNAPEIVYVS CNPKTLVNDL GVLRAYGYEV EKVKIVDMFP GTGHVETVVL 450
    LQRKII 456
    Length:456
    Mass (Da):51,312
    Last modified:October 1, 2001 - v1
    Checksum:i2F163B07786725A0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001437 Genomic DNA. Translation: AAK79403.1.
    PIRiH97076.
    RefSeqiNP_348063.1. NC_003030.1.
    WP_010964744.1. NC_003030.1.

    Genome annotation databases

    EnsemblBacteriaiAAK79403; AAK79403; CA_C1435.
    GeneIDi1117618.
    KEGGicac:CA_C1435.
    PATRICi32037253. VBICloAce74127_1640.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001437 Genomic DNA. Translation: AAK79403.1 .
    PIRi H97076.
    RefSeqi NP_348063.1. NC_003030.1.
    WP_010964744.1. NC_003030.1.

    3D structure databases

    ProteinModelPortali Q97J51.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272562.CA_C1435.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK79403 ; AAK79403 ; CA_C1435 .
    GeneIDi 1117618.
    KEGGi cac:CA_C1435.
    PATRICi 32037253. VBICloAce74127_1640.

    Phylogenomic databases

    eggNOGi COG2265.
    HOGENOMi HOG000029870.
    KOi K00599.
    OMAi CGGCTYQ.
    OrthoDBi EOG6V4GKM.

    Enzyme and pathway databases

    BioCyci CACE272562:GJIH-1484-MONOMER.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    3.40.50.150. 1 hit.
    InterProi IPR001566. 23S_rRNA_MeTrfase_RlmD.
    IPR012340. NA-bd_OB-fold.
    IPR029063. SAM-dependent_MTases-like.
    IPR002792. TRAM_dom.
    IPR010280. U5_MeTrfase_fam.
    [Graphical view ]
    Pfami PF05958. tRNA_U5-meth_tr. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    SSF53335. SSF53335. 1 hit.
    TIGRFAMsi TIGR00479. rumA. 1 hit.
    PROSITEi PS51687. SAM_MT_RNA_M5U. 1 hit.
    PS50926. TRAM. 1 hit.
    PS01230. TRMA_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

    Entry informationi

    Entry nameiY1435_CLOAB
    AccessioniPrimary (citable) accession number: Q97J51
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 19, 2004
    Last sequence update: October 1, 2001
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3