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Q97IC2 (PKN2_CLOAB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable serine/threonine-protein kinase CA_C1728

EC=2.7.11.1
Gene names
Ordered Locus Names:CA_C1728
OrganismClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) [Reference proteome] [HAMAP]
Taxonomic identifier272562 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length657 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 3 PASTA domains.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 657657Probable serine/threonine-protein kinase CA_C1728
PRO_0000171194

Regions

Domain10 – 274265Protein kinase
Domain375 – 44167PASTA 1
Domain443 – 50967PASTA 2
Domain512 – 57766PASTA 3
Nucleotide binding16 – 249ATP By similarity
Compositional bias587 – 65266Asn-rich

Sites

Active site1431Proton acceptor By similarity
Binding site391ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q97IC2 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: 0901452EF42E2CA6

FASTA65771,115
        10         20         30         40         50         60 
MIGTVLSNRY KIEEEIGVGG TAVVYKAMDT LLNRHVAVKV LKHEFTEDEE FVFKFKREAS 

        70         80         90        100        110        120 
AAARIANANI VNIYDVGADG NVNYIVMEYV AGKTLKKLIK ENGKIEFNKI IDYATQIAKA 

       130        140        150        160        170        180 
LNFAHKNGIV HRDIKPHNIM VTDDDIIKVT DFGIAKASNE STITTTNKVV GSAHYLSPEQ 

       190        200        210        220        230        240 
AQGIPVDCRT DIYSFGIVLY EMATGKVPYD ADTPVSIALK HIQDAAVPPN ELNKDIPIAL 

       250        260        270        280        290        300 
NKMILRCIEK KPENRYQNAN EILDELSNVK NNYVNDDEEF TRVMDPAQIQ NESNPNNKLD 

       310        320        330        340        350        360 
NDDTYYNGEP YNKEQPQEEP QEENEEPKNK IKGNNMLSGK AKKALVASII VVLILAGSAL 

       370        380        390        400        410        420 
AFSMGSGIFK PNSNSVSKVK VPKIIGLSES DAKGKVEDAK LKFQVVDRVK SSKPKGTVVT 

       430        440        450        460        470        480 
CYPNEDTEVD SGTVVRVDIS SGDTDQTLPS LVGLPESAAR AQIKQYGCNV GSVTQEYSDD 

       490        500        510        520        530        540 
VAQGNVISQS PSEGSQIKKG MTIDLVISRG PEVKKATVPS VYGKTSDSAS SILQNAGFGV 

       550        560        570        580        590        600 
NVQNKDVTNA DQNGIVIEEY PNGYVNKGTT VTIVIGRFNS TAVQPPNNNN GNGNQNQNQN 

       610        620        630        640        650 
KTPDTNHDDS KAPTGGNNDN QNQNNTTNPN GTQPAGGNVT GTGNGNVTNT PNGTGQK 

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References

[1]"Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum."
Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R., Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F., Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V., Smith D.R.
J. Bacteriol. 183:4823-4838(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE001437 Genomic DNA. Translation: AAK79694.1.
PIRC97113.
RefSeqNP_348354.1. NC_003030.1.

3D structure databases

ProteinModelPortalQ97IC2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272562.CA_C1728.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK79694; AAK79694; CA_C1728.
GeneID1117911.
KEGGcac:CA_C1728.
PATRIC32037834. VBICloAce74127_1930.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000037185.
KOK08884.
OMAIKIMRAD.
OrthoDBEOG6B35XT.

Enzyme and pathway databases

BioCycCACE272562:GJIH-1777-MONOMER.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR005543. PASTA.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00740. PASTA. 3 hits.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKN2_CLOAB
AccessionPrimary (citable) accession number: Q97IC2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: October 1, 2001
Last modified: May 14, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families