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Q97IC2

- PKN2_CLOAB

UniProt

Q97IC2 - PKN2_CLOAB

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Protein

Probable serine/threonine-protein kinase CA_C1728

Gene

CA_C1728

Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei39 – 391ATPPROSITE-ProRule annotation
Active sitei143 – 1431Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 249ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCACE272562:GJIH-1777-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase CA_C1728 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:CA_C1728
OrganismiClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Taxonomic identifieri272562 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000814: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 657657Probable serine/threonine-protein kinase CA_C1728PRO_0000171194Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272562.CA_C1728.

Structurei

3D structure databases

ProteinModelPortaliQ97IC2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 274265Protein kinasePROSITE-ProRule annotationAdd
BLAST
Domaini375 – 44167PASTA 1PROSITE-ProRule annotationAdd
BLAST
Domaini443 – 50967PASTA 2PROSITE-ProRule annotationAdd
BLAST
Domaini512 – 57766PASTA 3PROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi587 – 65266Asn-richAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 3 PASTA domains.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037185.
KOiK08884.
OMAiIKIMRAD.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 3 hits.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q97IC2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIGTVLSNRY KIEEEIGVGG TAVVYKAMDT LLNRHVAVKV LKHEFTEDEE
60 70 80 90 100
FVFKFKREAS AAARIANANI VNIYDVGADG NVNYIVMEYV AGKTLKKLIK
110 120 130 140 150
ENGKIEFNKI IDYATQIAKA LNFAHKNGIV HRDIKPHNIM VTDDDIIKVT
160 170 180 190 200
DFGIAKASNE STITTTNKVV GSAHYLSPEQ AQGIPVDCRT DIYSFGIVLY
210 220 230 240 250
EMATGKVPYD ADTPVSIALK HIQDAAVPPN ELNKDIPIAL NKMILRCIEK
260 270 280 290 300
KPENRYQNAN EILDELSNVK NNYVNDDEEF TRVMDPAQIQ NESNPNNKLD
310 320 330 340 350
NDDTYYNGEP YNKEQPQEEP QEENEEPKNK IKGNNMLSGK AKKALVASII
360 370 380 390 400
VVLILAGSAL AFSMGSGIFK PNSNSVSKVK VPKIIGLSES DAKGKVEDAK
410 420 430 440 450
LKFQVVDRVK SSKPKGTVVT CYPNEDTEVD SGTVVRVDIS SGDTDQTLPS
460 470 480 490 500
LVGLPESAAR AQIKQYGCNV GSVTQEYSDD VAQGNVISQS PSEGSQIKKG
510 520 530 540 550
MTIDLVISRG PEVKKATVPS VYGKTSDSAS SILQNAGFGV NVQNKDVTNA
560 570 580 590 600
DQNGIVIEEY PNGYVNKGTT VTIVIGRFNS TAVQPPNNNN GNGNQNQNQN
610 620 630 640 650
KTPDTNHDDS KAPTGGNNDN QNQNNTTNPN GTQPAGGNVT GTGNGNVTNT

PNGTGQK
Length:657
Mass (Da):71,115
Last modified:October 1, 2001 - v1
Checksum:i0901452EF42E2CA6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001437 Genomic DNA. Translation: AAK79694.1.
PIRiC97113.
RefSeqiNP_348354.1. NC_003030.1.

Genome annotation databases

EnsemblBacteriaiAAK79694; AAK79694; CA_C1728.
GeneIDi1117911.
KEGGicac:CA_C1728.
PATRICi32037834. VBICloAce74127_1930.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001437 Genomic DNA. Translation: AAK79694.1 .
PIRi C97113.
RefSeqi NP_348354.1. NC_003030.1.

3D structure databases

ProteinModelPortali Q97IC2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272562.CA_C1728.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK79694 ; AAK79694 ; CA_C1728 .
GeneIDi 1117911.
KEGGi cac:CA_C1728.
PATRICi 32037834. VBICloAce74127_1930.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000037185.
KOi K08884.
OMAi IKIMRAD.
OrthoDBi EOG6B35XT.

Enzyme and pathway databases

BioCyci CACE272562:GJIH-1777-MONOMER.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00740. PASTA. 3 hits.
SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

Entry informationi

Entry nameiPKN2_CLOAB
AccessioniPrimary (citable) accession number: Q97IC2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: October 1, 2001
Last modified: October 29, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3