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Q97IC2

- PKN2_CLOAB

UniProt

Q97IC2 - PKN2_CLOAB

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Protein
Probable serine/threonine-protein kinase CA_C1728
Gene
CA_C1728
Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei39 – 391ATP By similarity
Active sitei143 – 1431Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 249ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCACE272562:GJIH-1777-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable serine/threonine-protein kinase CA_C1728 (EC:2.7.11.1)
    Gene namesi
    Ordered Locus Names:CA_C1728
    OrganismiClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
    Taxonomic identifieri272562 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000000814: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 657657Probable serine/threonine-protein kinase CA_C1728
    PRO_0000171194Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272562.CA_C1728.

    Structurei

    3D structure databases

    ProteinModelPortaliQ97IC2.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 274265Protein kinase
    Add
    BLAST
    Domaini375 – 44167PASTA 1
    Add
    BLAST
    Domaini443 – 50967PASTA 2
    Add
    BLAST
    Domaini512 – 57766PASTA 3
    Add
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi587 – 65266Asn-rich
    Add
    BLAST

    Sequence similaritiesi

    Contains 3 PASTA domains.

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000037185.
    KOiK08884.
    OMAiIKIMRAD.
    OrthoDBiEOG6B35XT.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF03793. PASTA. 3 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00740. PASTA. 3 hits.
    SM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS51178. PASTA. 3 hits.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q97IC2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIGTVLSNRY KIEEEIGVGG TAVVYKAMDT LLNRHVAVKV LKHEFTEDEE    50
    FVFKFKREAS AAARIANANI VNIYDVGADG NVNYIVMEYV AGKTLKKLIK 100
    ENGKIEFNKI IDYATQIAKA LNFAHKNGIV HRDIKPHNIM VTDDDIIKVT 150
    DFGIAKASNE STITTTNKVV GSAHYLSPEQ AQGIPVDCRT DIYSFGIVLY 200
    EMATGKVPYD ADTPVSIALK HIQDAAVPPN ELNKDIPIAL NKMILRCIEK 250
    KPENRYQNAN EILDELSNVK NNYVNDDEEF TRVMDPAQIQ NESNPNNKLD 300
    NDDTYYNGEP YNKEQPQEEP QEENEEPKNK IKGNNMLSGK AKKALVASII 350
    VVLILAGSAL AFSMGSGIFK PNSNSVSKVK VPKIIGLSES DAKGKVEDAK 400
    LKFQVVDRVK SSKPKGTVVT CYPNEDTEVD SGTVVRVDIS SGDTDQTLPS 450
    LVGLPESAAR AQIKQYGCNV GSVTQEYSDD VAQGNVISQS PSEGSQIKKG 500
    MTIDLVISRG PEVKKATVPS VYGKTSDSAS SILQNAGFGV NVQNKDVTNA 550
    DQNGIVIEEY PNGYVNKGTT VTIVIGRFNS TAVQPPNNNN GNGNQNQNQN 600
    KTPDTNHDDS KAPTGGNNDN QNQNNTTNPN GTQPAGGNVT GTGNGNVTNT 650
    PNGTGQK 657
    Length:657
    Mass (Da):71,115
    Last modified:October 1, 2001 - v1
    Checksum:i0901452EF42E2CA6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001437 Genomic DNA. Translation: AAK79694.1.
    PIRiC97113.
    RefSeqiNP_348354.1. NC_003030.1.

    Genome annotation databases

    EnsemblBacteriaiAAK79694; AAK79694; CA_C1728.
    GeneIDi1117911.
    KEGGicac:CA_C1728.
    PATRICi32037834. VBICloAce74127_1930.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001437 Genomic DNA. Translation: AAK79694.1 .
    PIRi C97113.
    RefSeqi NP_348354.1. NC_003030.1.

    3D structure databases

    ProteinModelPortali Q97IC2.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 272562.CA_C1728.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK79694 ; AAK79694 ; CA_C1728 .
    GeneIDi 1117911.
    KEGGi cac:CA_C1728.
    PATRICi 32037834. VBICloAce74127_1930.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000037185.
    KOi K08884.
    OMAi IKIMRAD.
    OrthoDBi EOG6B35XT.

    Enzyme and pathway databases

    BioCyci CACE272562:GJIH-1777-MONOMER.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF03793. PASTA. 3 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00740. PASTA. 3 hits.
    SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS51178. PASTA. 3 hits.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

    Entry informationi

    Entry nameiPKN2_CLOAB
    AccessioniPrimary (citable) accession number: Q97IC2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2003
    Last sequence update: October 1, 2001
    Last modified: September 3, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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