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Q97IC2

- PKN2_CLOAB

UniProt

Q97IC2 - PKN2_CLOAB

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Protein

Probable serine/threonine-protein kinase CA_C1728

Gene
CA_C1728
Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei39 – 391ATP By similarity
Active sitei143 – 1431Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 249ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCACE272562:GJIH-1777-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase CA_C1728 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:CA_C1728
OrganismiClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Taxonomic identifieri272562 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000814: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 657657Probable serine/threonine-protein kinase CA_C1728PRO_0000171194Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272562.CA_C1728.

Structurei

3D structure databases

ProteinModelPortaliQ97IC2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 274265Protein kinaseAdd
BLAST
Domaini375 – 44167PASTA 1Add
BLAST
Domaini443 – 50967PASTA 2Add
BLAST
Domaini512 – 57766PASTA 3Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi587 – 65266Asn-richAdd
BLAST

Sequence similaritiesi

Contains 3 PASTA domains.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037185.
KOiK08884.
OMAiIKIMRAD.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 3 hits.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q97IC2-1 [UniParc]FASTAAdd to Basket

« Hide

MIGTVLSNRY KIEEEIGVGG TAVVYKAMDT LLNRHVAVKV LKHEFTEDEE    50
FVFKFKREAS AAARIANANI VNIYDVGADG NVNYIVMEYV AGKTLKKLIK 100
ENGKIEFNKI IDYATQIAKA LNFAHKNGIV HRDIKPHNIM VTDDDIIKVT 150
DFGIAKASNE STITTTNKVV GSAHYLSPEQ AQGIPVDCRT DIYSFGIVLY 200
EMATGKVPYD ADTPVSIALK HIQDAAVPPN ELNKDIPIAL NKMILRCIEK 250
KPENRYQNAN EILDELSNVK NNYVNDDEEF TRVMDPAQIQ NESNPNNKLD 300
NDDTYYNGEP YNKEQPQEEP QEENEEPKNK IKGNNMLSGK AKKALVASII 350
VVLILAGSAL AFSMGSGIFK PNSNSVSKVK VPKIIGLSES DAKGKVEDAK 400
LKFQVVDRVK SSKPKGTVVT CYPNEDTEVD SGTVVRVDIS SGDTDQTLPS 450
LVGLPESAAR AQIKQYGCNV GSVTQEYSDD VAQGNVISQS PSEGSQIKKG 500
MTIDLVISRG PEVKKATVPS VYGKTSDSAS SILQNAGFGV NVQNKDVTNA 550
DQNGIVIEEY PNGYVNKGTT VTIVIGRFNS TAVQPPNNNN GNGNQNQNQN 600
KTPDTNHDDS KAPTGGNNDN QNQNNTTNPN GTQPAGGNVT GTGNGNVTNT 650
PNGTGQK 657
Length:657
Mass (Da):71,115
Last modified:October 1, 2001 - v1
Checksum:i0901452EF42E2CA6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001437 Genomic DNA. Translation: AAK79694.1.
PIRiC97113.
RefSeqiNP_348354.1. NC_003030.1.

Genome annotation databases

EnsemblBacteriaiAAK79694; AAK79694; CA_C1728.
GeneIDi1117911.
KEGGicac:CA_C1728.
PATRICi32037834. VBICloAce74127_1930.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001437 Genomic DNA. Translation: AAK79694.1 .
PIRi C97113.
RefSeqi NP_348354.1. NC_003030.1.

3D structure databases

ProteinModelPortali Q97IC2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272562.CA_C1728.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK79694 ; AAK79694 ; CA_C1728 .
GeneIDi 1117911.
KEGGi cac:CA_C1728.
PATRICi 32037834. VBICloAce74127_1930.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000037185.
KOi K08884.
OMAi IKIMRAD.
OrthoDBi EOG6B35XT.

Enzyme and pathway databases

BioCyci CACE272562:GJIH-1777-MONOMER.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00740. PASTA. 3 hits.
SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

Entry informationi

Entry nameiPKN2_CLOAB
AccessioniPrimary (citable) accession number: Q97IC2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: October 1, 2001
Last modified: September 3, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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