Reviewed, UniProtKB/Swiss-Prot Q97GX6 (GLGA_CLOAB)

Names and origin

Protein names

Recommended name:
    Glycogen synthase
    EC=2.4.1.21
Alternative name(s):
    Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	CA_C2239

Organism

Clostridium acetobutylicum [Complete proteome] [HAMAP]

Taxonomic identifier

1488 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	477 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 477	477	Glycogen synthase HAMAP MF_00484		PRO_0000188607
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q97GX6-1 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 974122C6A46FAAD6	FASTA	477	55,070
	10 20 30 40 50 60 MKILFASSES YPFIKTGGLG DVSYALPKAL RKIGIDARVI IPKYSDIPEY FRYNTHHIAS 70 80 90 100 110 120 FGVPVGWRSQ YGGLEYYEYD GVPFYFIDND YYFKRSGLYG YYDDGERFAY FSRGVLQAIT 130 140 150 160 170 180 YMQDFNPDII QCNDWQTAII PVLLKDHYRN YRNYNHIKTI FTIHNLKYQG VFGKSVLGEL 190 200 210 220 230 240 LCLNEGYYNE NALKFYDGIS FMKGGILFSD KLSTVSRTYA EEIKDPYYGE HLDGLLRSRS 250 260 270 280 290 300 YDLWGIVNGI DYDILNPETD KDLFFNFDSS TLYNKTKNKI ELQKMLNLPV SENIPMIGIV 310 320 330 340 350 360 SRLVSQKGLD LISCVLEDLL QDGIQLVVLG TGDAKYENMF KYFAWKYPNK LSANIQFNNS 370 380 390 400 410 420 LAQKIYGASD MFLMPSKFEP CGIGQLIALR YGSLPIVRET GGLKDTVRPF NPITGEGNGF 430 440 450 460 470 SFTNYNAHDM LHVIRNAEYF YYNEKYNWNK LVQTAMNDDN SWSKSAEIYR NLYMSVL

References

[1]

"Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum." Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R., Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F., Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V., Smith D.R. J. Bacteriol. 183:4823-4838(2001) [PubMed: 11466286] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE001437 Genomic DNA. Translation: AAK80196.1.
PIR	A97176.
RefSeq	NP_348856.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT5. Glycosyltransferase Family 5.
Genome annotation databases
GeneID	1118422.
GenomeReviews	Gene locus CA_C2239 in contig AE001437_GR.
KEGG	cac:CAC2239.
NMPDR	fig|272562.1.peg.2385.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q97GX6.
OMA	YQGPWRW.
Enzyme and pathway databases
BioCyc	CACE272562:CAC2239-MON.
BRENDA	2.4.1.21. 2866.
Family and domain databases
HAMAP	MF_00484. [Tree]
InterPro	IPR011835. GlgA. IPR001296. Glyco_trans_1. IPR013534. Glyco_transf_5. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_CLOAB

Accession

Primary (citable) accession number: Q97GX6

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 16, 2001
Last sequence update:	October 1, 2001
Last modified:	November 3, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)