ID   Q97G25_CLOAB            Unreviewed;       665 AA.
AC   Q97G25;
DT   01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2001, sequence version 1.
DT   27-MAR-2024, entry version 112.
DE   SubName: Full=Possible membrane-associated methyl-accepting chemotaxis protein fused to HAMP domain {ECO:0000313|EMBL:AAK80498.1};
GN   OrderedLocusNames=CA_C2547 {ECO:0000313|EMBL:AAK80498.1};
OS   Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS   / VKM B-1787).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=272562 {ECO:0000313|EMBL:AAK80498.1, ECO:0000313|Proteomes:UP000000814};
RN   [1] {ECO:0000313|EMBL:AAK80498.1, ECO:0000313|Proteomes:UP000000814}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787
RC   {ECO:0000313|Proteomes:UP000000814};
RX   PubMed=11466286; DOI=10.1128/JB.183.16.4823-4838.2001;
RA   Nolling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA   Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA   Doucette-Stamm L., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA   Smith D.R.;
RT   "Genome sequence and comparative analysis of the solvent-producing
RT   bacterium Clostridium acetobutylicum.";
RL   J. Bacteriol. 183:4823-4838(2001).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE001437; AAK80498.1; -; Genomic_DNA.
DR   PIR; G97213; G97213.
DR   RefSeq; NP_349158.1; NC_003030.1.
DR   RefSeq; WP_010965839.1; NC_003030.1.
DR   AlphaFoldDB; Q97G25; -.
DR   STRING; 272562.CA_C2547; -.
DR   GeneID; 44999019; -.
DR   KEGG; cac:CA_C2547; -.
DR   PATRIC; fig|272562.8.peg.2739; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   OrthoDB; 13222at2; -.
DR   Proteomes; UP000000814; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd18773; PDC1_HK_sensor; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 1.10.8.500; HAMP domain in histidine kinase; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000814};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        15..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        284..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          308..360
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          379..636
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   665 AA;  72045 MW;  322FC576710BE345 CRC64;
     MQFKRASLNS IRSKLIISLI SICVIPLLII GTFSYNYAKS ILNSKLNVTS TQTLNEVNDG
     LINYFHGLSD IISMTAKNPP IINIDSDNNT QLISEILGGV KNSDNDILDA YYGTASGKFI
     MYPDTKMPDG FDATTRDWYK RAVASKGEVI ITPPFKDVVT GNMVVGIAKA VEKDGKVVGV
     IGIDCTLSTL ADKIATKKIG NSGYVFIANG DGIILAHPNK SIINTNEAGK LPFWGETKTK
     DSGFVTYTYK DIKKFGVYKT NKLTGWKVVA TLEQSELTSD TKSILLTTSI IVLIMALVAA
     VLSLVLSKGI ANNINKLKDV FAKASNGDLS NFIEVKTKDE FGQLARDYNS MIKNIGMLLS
     NAKKTSNTVL DTTSSLSSMA EETLASMSQV ALAVSEISTA AVSLAENSGE TANGIGELST
     KLDDVAGITE DMSNVSSDTK NLSKQGINTV SVLISKNSET MEASMKVFDI VSDMDNSVKE
     ISTISDAINE ITEQTNLLSL NASIEAARAG EAGKGFAVVA DEIRKLAEQS KASTEQIKLI
     IENIQEKANT AVKAMDSNKN INLEQNKVVE KTEQIFNDIL MSITNLTEKV DNVKMSVESM
     QTQKQEFVAQ VENTSAISEE TASSIEEVTA STEEVTATMD KFTQHTVEVQ ELAEKLKEEI
     YKFKV
//