ID   Q97FV9_CLOAB            Unreviewed;       664 AA.
AC   Q97FV9;
DT   01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2001, sequence version 1.
DT   27-MAR-2024, entry version 114.
DE   SubName: Full=Membrane associated methyl-chemotaxis protein, HAMP domain containing {ECO:0000313|EMBL:AAK80564.1};
GN   OrderedLocusNames=CA_C2617 {ECO:0000313|EMBL:AAK80564.1};
OS   Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS   / VKM B-1787).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=272562 {ECO:0000313|EMBL:AAK80564.1, ECO:0000313|Proteomes:UP000000814};
RN   [1] {ECO:0000313|EMBL:AAK80564.1, ECO:0000313|Proteomes:UP000000814}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787
RC   {ECO:0000313|Proteomes:UP000000814};
RX   PubMed=11466286; DOI=10.1128/JB.183.16.4823-4838.2001;
RA   Nolling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA   Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA   Doucette-Stamm L., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA   Smith D.R.;
RT   "Genome sequence and comparative analysis of the solvent-producing
RT   bacterium Clostridium acetobutylicum.";
RL   J. Bacteriol. 183:4823-4838(2001).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE001437; AAK80564.1; -; Genomic_DNA.
DR   PIR; A97222; A97222.
DR   RefSeq; NP_349224.1; NC_003030.1.
DR   RefSeq; WP_010965905.1; NC_003030.1.
DR   AlphaFoldDB; Q97FV9; -.
DR   STRING; 272562.CA_C2617; -.
DR   GeneID; 44999085; -.
DR   KEGG; cac:CA_C2617; -.
DR   PATRIC; fig|272562.8.peg.2806; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   OrthoDB; 597657at2; -.
DR   Proteomes; UP000000814; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd12914; PDC1_DGC_like; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 2.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000814};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        9..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          304..359
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          378..628
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          623..650
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   664 AA;  72064 MW;  B07ABFC7D40D22D9 CRC64;
     MKSIKGKILL MIETLIIVVI VGMGILAGML SSNALRNNNE SIMPQIAKSA ASYISAKVDD
     KKNMVEQITF NSVINNSDKS LDEKLAVLND ENKRYKFIKI GIADLNGNVK YNNLTSTNIA
     NREYFKKALS GEIAVSNPII GKIEKNLEVC FAAPIRQNGN ITGILVAIND GNIISSIADE
     VKFGSTGRVF AIDNTGVKIA NYNKTLVAKQ DNDFVNVKKN PSLEELVSIE RNMAQGKTGS
     GYYTYGGNKK FAAFAPIKNT TWSLAVIVEQ SEMDNQLSKL QKYTAGLAVL FLALAFLIVY
     LVANNLAKRI KVATDYIVPI SNGDFTVEVS KEHIGMKDEI GVMVQAIDNM QKSIKGMLRA
     VVENSNKISE DSESLSSIAE EMNSSAEAVT LAVGEVTKGA TSQAEEMSDI TETINEFVSS
     LDEITAEVND VDVNSKNIID LAKDSWIKMN KLATSIKEVT NTFKDFEVKI VQSSEHIKNI
     NEITDFINSI AEQTNLLALN AAIEAARAGE AGKGFSVVSD EIRKLAEQAG QSAEKISGLV
     GEVYNENKSM VTTTSKVGND LENQISVVDN ALESFTGIVT SINEVIPKIN QINRAVVDLN
     NNKDIISNKV EATAAISEET SAASEEISAS SQEMNTSSST VAKSAANLND RTREMMNEVK
     KFKL
//