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Q97FP8

- G6PI_CLOAB

UniProt

Q97FP8 - G6PI_CLOAB

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 Oct 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei291 – 2911Proton donorBy similarity
    Active sitei312 – 3121By similarity
    Active sitei426 – 4261By similarity

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciCACE272562:GJIH-2758-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomerase (EC:5.3.1.9)
    Short name:
    GPI
    Alternative name(s):
    Phosphoglucose isomerase
    Short name:
    PGI
    Phosphohexose isomerase
    Short name:
    PHI
    Gene namesi
    Name:pgi
    Ordered Locus Names:CA_C2680
    OrganismiClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
    Taxonomic identifieri272562 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000000814: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 450450Glucose-6-phosphate isomerasePRO_0000180626Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272562.CA_C2680.

    Structurei

    3D structure databases

    ProteinModelPortaliQ97FP8.
    SMRiQ97FP8. Positions 7-449.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.Curated

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100403.
    KOiK01810.
    OMAiGVESYKR.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q97FP8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSECFKLELK NTKPYLQDEE LKNLKPAVAA AHEAIHNGTG AGNDFLGWVD    50
    LPVNYDKDEF ERIKKSAEKI RNSVDAFIVI GIGGSYLGAR AAIEMFSHSF 100
    SSSISKEERK NPEIFFCGNN ISSTYLADLL EAIEGKDIAV NVISKSGTTT 150
    EPAIAFRIFK ELLEKKYGKE EAKNRIFATT DAKKGALKTL SDNEGYETFV 200
    VPDDVGGRYS VLTAVGLLPI AVAGIDIDEM MKGAAKAREV YSEPDLEKNE 250
    AYQYAAARNA LYSKGKSIEM VVNFEPSLHY FGEWWKQLFG ESEGKDGKGL 300
    FPAAGDFSTD LHSMGQYIQE GRRQLIETFI NVVNPKKEVT IQKDAENLDG 350
    LNFVAGKTMD FVNKQAFMGT VLAHHDGGVP VMVVNVPELT AYYFGYMVYF 400
    FEKACGISGY LLGVNPFNQP GVEAYKKNMF ALLGKPGYED LAKELNNKLK 450
    Length:450
    Mass (Da):49,791
    Last modified:October 1, 2001 - v1
    Checksum:iD01B3ABDB64878FC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001437 Genomic DNA. Translation: AAK80627.1.
    PIRiH97229.
    RefSeqiNP_349287.1. NC_003030.1.

    Genome annotation databases

    EnsemblBacteriaiAAK80627; AAK80627; CA_C2680.
    GeneIDi1118863.
    KEGGicac:CA_C2680.
    PATRICi32039775. VBICloAce74127_2871.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001437 Genomic DNA. Translation: AAK80627.1 .
    PIRi H97229.
    RefSeqi NP_349287.1. NC_003030.1.

    3D structure databases

    ProteinModelPortali Q97FP8.
    SMRi Q97FP8. Positions 7-449.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272562.CA_C2680.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK80627 ; AAK80627 ; CA_C2680 .
    GeneIDi 1118863.
    KEGGi cac:CA_C2680.
    PATRICi 32039775. VBICloAce74127_2871.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100403.
    KOi K01810.
    OMAi GVESYKR.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci CACE272562:GJIH-2758-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

    Entry informationi

    Entry nameiG6PI_CLOAB
    AccessioniPrimary (citable) accession number: Q97FP8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 2, 2001
    Last sequence update: October 1, 2001
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3