Reviewed, UniProtKB/Swiss-Prot Q97EZ4 (GALT_CLOAB)

Names and origin

Protein names

Recommended name:
    Galactose-1-phosphate uridylyltransferase
      Short name=Gal-1-P uridylyltransferase
    EC=2.7.7.12
Alternative name(s):
    UDP-glucose--hexose-1-phosphate uridylyltransferase

Gene names

Name:	galT
Ordered Locus Names:	CA_C2961

Organism

Clostridium acetobutylicum [Complete proteome] [HAMAP]

Taxonomic identifier

1488 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	497 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 497	497	Galactose-1-phosphate uridylyltransferase HAMAP MF_00571		PRO_0000169902

Sequences

	Sequence		Length	Mass (Da)
	Q97EZ4-1 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 81E9D089CDA9F5CC	FASTA	497	57,289
	10 20 30 40 50 60 MINHEINKLL AFSLKKGLIQ EDDKIYSSNM LAGLFNLDNF YFEEISDVPS TATAILNQLL 70 80 90 100 110 120 AYAVKENLIN DTVAERDLFD TKIMNCVMPR PSEVINNFNR LLNNSPKEAT SYYYKLSIAS 130 140 150 160 170 180 NYIRKDRIDK NITWKTPTEY GDLDITINLS KPEKDPRDIA KAKLSKSTSY PKCLLCKENE 190 200 210 220 230 240 GFYGNINHPA RQTLRIIPLE LNKSKWFLQY SPYTYYNEHC IILNNEHIPM KISRITFENL 250 260 270 280 290 300 LSFIDILPHY FAGSNADLPI VGGSILSHDH YQGGRYTFAM EKAPVEKEYS IKGYEDISVG 310 320 330 340 350 360 RVKWPMSVIR ISSKNKTKLI NLAEHILTSW RNYSDKTQSI LSHTGSEPHN TITPIARKRN 370 380 390 400 410 420 EEYELDLVLR NNRTDENYPL GIFHPHNEVH HIKKENIGLI EVMGLAVLPA RLKSELALIK 430 440 450 460 470 480 ENLIEKKKDI SNDSTISKHN TWYKYILDNY KNISEENIDC ILKKEVGIKF LEVLKHAGVF 490 KRNSSGLSAF DKFINIL

References

[1]

"Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum." Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R., Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F., Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V., Smith D.R. J. Bacteriol. 183:4823-4838(2001) [PubMed: 11466286] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE001437 Genomic DNA. Translation: AAK80903.1.
PIR	D97264.
RefSeq	NP_349563.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1119144.
GenomeReviews	Gene locus CA_C2961 in contig AE001437_GR.
KEGG	cac:CAC2961.
NMPDR	fig|272562.1.peg.3092.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q97EZ4.
OMA	EHYQGGR.
Enzyme and pathway databases
BioCyc	CACE272562:CAC2961-MON.
BRENDA	2.7.7.12. 2866.
Family and domain databases
HAMAP	MF_00571. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
TIGRFAMs	TIGR01239. galT_2. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT_CLOAB

Accession

Primary (citable) accession number: Q97EZ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 26, 2002
Last sequence update:	October 1, 2001
Last modified:	November 3, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)