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Q97EZ2

- LACG_CLOAB

UniProt

Q97EZ2 - LACG_CLOAB

Protein

6-phospho-beta-galactosidase

Gene

lacG

Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 Oct 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    A 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei160 – 1601Proton donorUniRule annotation
    Active sitei374 – 3741NucleophileUniRule annotation

    GO - Molecular functioni

    1. 6-phospho-beta-galactosidase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. lactose catabolic process via tagatose-6-phosphate Source: InterPro

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Enzyme and pathway databases

    BioCyciCACE272562:GJIH-3046-MONOMER.
    UniPathwayiUPA00542; UER00605.

    Protein family/group databases

    CAZyiGH1. Glycoside Hydrolase Family 1.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    6-phospho-beta-galactosidaseUniRule annotation (EC:3.2.1.85UniRule annotation)
    Alternative name(s):
    Beta-D-phosphogalactoside galactohydrolaseUniRule annotation
    Short name:
    PGALaseUniRule annotation
    P-beta-GalUniRule annotation
    Short name:
    PBGUniRule annotation
    Gene namesi
    Name:lacGUniRule annotation
    Ordered Locus Names:CA_C2963
    OrganismiClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
    Taxonomic identifieri272562 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000000814: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 4744746-phospho-beta-galactosidasePRO_0000260722Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272562.CA_C2963.

    Structurei

    3D structure databases

    ProteinModelPortaliQ97EZ2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2723.
    HOGENOMiHOG000088632.
    KOiK01220.
    OMAiANESIPR.
    OrthoDBiEOG60658J.

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    HAMAPiMF_01574. LacG.
    InterProiIPR005928. 6P-beta-galactosidase.
    IPR001360. Glyco_hydro_1.
    IPR018120. Glyco_hydro_1_AS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PANTHERiPTHR10353. PTHR10353. 1 hit.
    PfamiPF00232. Glyco_hydro_1. 1 hit.
    [Graphical view]
    PRINTSiPR00131. GLHYDRLASE1.
    SUPFAMiSSF51445. SSF51445. 1 hit.
    TIGRFAMsiTIGR01233. lacG. 1 hit.
    PROSITEiPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
    PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q97EZ2-1 [UniParc]FASTAAdd to Basket

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    MNNFGEDFIF GGATAAYQAE GATKEDGKGP CIWDEYLKKE GRFTGDTASD    50
    FYHKYKEDLK FSRKFGVNGI RISIAWSRVI PDGKGEVNPK GLKFYSDLID 100
    ECIKNNVEPF VTLHHFDTPL TLFKDGDWLN RNNIDYFVRF AKVCFEALGD 150
    RVKKWITFNE AWAVAQNGYI IGNFPPSIKY DIPKAAQSMH NMMVAHAKVV 200
    ELYKSMNLDG EIGIVHTLEG KYPITDSKED KEAAYLDYMI SNKFMLDACF 250
    KGEYPKETEK TINEIMSKNG GELKIYDGDL EVLKKASSKI DFLGMNYYSS 300
    HFLKAYEGES RIHHNGTGEK GTSIFALKGI GERVNNPEVP TTDWDWPIYP 350
    KGLHDMLVRI KNEYPNYKKI YVTENGMGYK DDFKDGKIDD TPRIDYINKH 400
    LEAILKAKNE GVVVKGYFVW SLMDVLSWSN GYNKRYGLFY VDFKTQNRYA 450
    KKSAYWFKRI SYEKKLIDFS DIEY 474
    Length:474
    Mass (Da):54,672
    Last modified:October 1, 2001 - v1
    Checksum:i5661CA39AAC5C3BE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001437 Genomic DNA. Translation: AAK80905.1.
    PIRiF97264.
    RefSeqiNP_349565.1. NC_003030.1.

    Genome annotation databases

    EnsemblBacteriaiAAK80905; AAK80905; CA_C2963.
    GeneIDi1119146.
    KEGGicac:CA_C2963.
    PATRICi32040337. VBICloAce74127_3147.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001437 Genomic DNA. Translation: AAK80905.1 .
    PIRi F97264.
    RefSeqi NP_349565.1. NC_003030.1.

    3D structure databases

    ProteinModelPortali Q97EZ2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272562.CA_C2963.

    Protein family/group databases

    CAZyi GH1. Glycoside Hydrolase Family 1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAK80905 ; AAK80905 ; CA_C2963 .
    GeneIDi 1119146.
    KEGGi cac:CA_C2963.
    PATRICi 32040337. VBICloAce74127_3147.

    Phylogenomic databases

    eggNOGi COG2723.
    HOGENOMi HOG000088632.
    KOi K01220.
    OMAi ANESIPR.
    OrthoDBi EOG60658J.

    Enzyme and pathway databases

    UniPathwayi UPA00542 ; UER00605 .
    BioCyci CACE272562:GJIH-3046-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    HAMAPi MF_01574. LacG.
    InterProi IPR005928. 6P-beta-galactosidase.
    IPR001360. Glyco_hydro_1.
    IPR018120. Glyco_hydro_1_AS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    PANTHERi PTHR10353. PTHR10353. 1 hit.
    Pfami PF00232. Glyco_hydro_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00131. GLHYDRLASE1.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    TIGRFAMsi TIGR01233. lacG. 1 hit.
    PROSITEi PS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
    PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

    Entry informationi

    Entry nameiLACG_CLOAB
    AccessioniPrimary (citable) accession number: Q97EZ2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 28, 2006
    Last sequence update: October 1, 2001
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3