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Q97EF4

- TRPF_CLOAB

UniProt

Q97EF4 - TRPF_CLOAB

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciCACE272562:GJIH-3244-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
Short name:
PRAIUniRule annotation
Gene namesi
Name:trpFUniRule annotation
Ordered Locus Names:CA_C3159
OrganismiClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Taxonomic identifieri272562 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000814: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 205205N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154356Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272562.CA_C3159.

Structurei

3D structure databases

ProteinModelPortaliQ97EF4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiTHDWEIS.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q97EF4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKIKVCGIR REEDIEIVNK YKPNYVGFVF AKSKRQVDMY KAEKLADKLD
60 70 80 90 100
VSIKKVGVFV NEDIEKVKEV SFRVKLDIVQ LHGDENEEYI DKLKGFKVWK
110 120 130 140 150
AVNVTAGKDV EKFKNYRIDA FLVDGYDGTN RGGTGKSFNW NLLKENQDKI
160 170 180 190 200
LKPIIAAGGL NIDNVEKCIE VLNPFAVDVS SGVETDGFKD EEKIKKFIMR

VRKFK
Length:205
Mass (Da):23,490
Last modified:October 1, 2001 - v1
Checksum:iEA6A1CCD8307B863
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001437 Genomic DNA. Translation: AAK81096.1.
PIRiE97288.
RefSeqiNP_349756.1. NC_003030.1.

Genome annotation databases

EnsemblBacteriaiAAK81096; AAK81096; CA_C3159.
GeneIDi1119341.
KEGGicac:CA_C3159.
PATRICi32040727. VBICloAce74127_3340.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001437 Genomic DNA. Translation: AAK81096.1 .
PIRi E97288.
RefSeqi NP_349756.1. NC_003030.1.

3D structure databases

ProteinModelPortali Q97EF4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272562.CA_C3159.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK81096 ; AAK81096 ; CA_C3159 .
GeneIDi 1119341.
KEGGi cac:CA_C3159.
PATRICi 32040727. VBICloAce74127_3340.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi THDWEIS.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci CACE272562:GJIH-3244-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

Entry informationi

Entry nameiTRPF_CLOAB
AccessioniPrimary (citable) accession number: Q97EF4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: October 1, 2001
Last modified: October 1, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3