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Q97EF4

- TRPF_CLOAB

UniProt

Q97EF4 - TRPF_CLOAB

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Protein
N-(5'-phosphoribosyl)anthranilate isomerase
Gene
trpF, CA_C3159
Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciCACE272562:GJIH-3244-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:CA_C3159
OrganismiClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Taxonomic identifieri272562 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000814: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 205205N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation
PRO_0000154356Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272562.CA_C3159.

Structurei

3D structure databases

ProteinModelPortaliQ97EF4.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiTHDWEIS.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q97EF4-1 [UniParc]FASTAAdd to Basket

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MVKIKVCGIR REEDIEIVNK YKPNYVGFVF AKSKRQVDMY KAEKLADKLD    50
VSIKKVGVFV NEDIEKVKEV SFRVKLDIVQ LHGDENEEYI DKLKGFKVWK 100
AVNVTAGKDV EKFKNYRIDA FLVDGYDGTN RGGTGKSFNW NLLKENQDKI 150
LKPIIAAGGL NIDNVEKCIE VLNPFAVDVS SGVETDGFKD EEKIKKFIMR 200
VRKFK 205
Length:205
Mass (Da):23,490
Last modified:October 1, 2001 - v1
Checksum:iEA6A1CCD8307B863
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001437 Genomic DNA. Translation: AAK81096.1.
PIRiE97288.
RefSeqiNP_349756.1. NC_003030.1.

Genome annotation databases

EnsemblBacteriaiAAK81096; AAK81096; CA_C3159.
GeneIDi1119341.
KEGGicac:CA_C3159.
PATRICi32040727. VBICloAce74127_3340.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001437 Genomic DNA. Translation: AAK81096.1 .
PIRi E97288.
RefSeqi NP_349756.1. NC_003030.1.

3D structure databases

ProteinModelPortali Q97EF4.
ModBasei Search...

Protein-protein interaction databases

STRINGi 272562.CA_C3159.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK81096 ; AAK81096 ; CA_C3159 .
GeneIDi 1119341.
KEGGi cac:CA_C3159.
PATRICi 32040727. VBICloAce74127_3340.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi THDWEIS.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci CACE272562:GJIH-3244-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

Entry informationi

Entry nameiTRPF_CLOAB
AccessioniPrimary (citable) accession number: Q97EF4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: October 1, 2001
Last modified: May 14, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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