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Protein

Probable 2-phosphosulfolactate phosphatase

Gene

comB

Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate.

Cofactori

Mg2+By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciCACE272562:GJIH-3329-MONOMER.
BRENDAi3.1.3.71. 1452.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 2-phosphosulfolactate phosphatase (EC:3.1.3.71)
Gene namesi
Name:comB
Ordered Locus Names:CA_C3233
OrganismiClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Taxonomic identifieri272562 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000000814 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 235235Probable 2-phosphosulfolactate phosphatasePRO_0000081465Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272562.CA_C3233.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi1 – 66Combined sources
Helixi9 – 113Combined sources
Helixi14 – 163Combined sources
Turni17 – 193Combined sources
Beta strandi20 – 256Combined sources
Turni27 – 293Combined sources
Helixi30 – 3910Combined sources
Beta strandi44 – 474Combined sources
Helixi51 – 6111Combined sources
Helixi62 – 643Combined sources
Beta strandi65 – 695Combined sources
Helixi85 – 873Combined sources
Helixi90 – 934Combined sources
Beta strandi97 – 1015Combined sources
Helixi105 – 1117Combined sources
Turni112 – 1143Combined sources
Beta strandi115 – 1217Combined sources
Helixi126 – 13611Combined sources
Beta strandi140 – 1445Combined sources
Helixi153 – 16917Combined sources
Beta strandi173 – 1753Combined sources
Helixi177 – 18711Combined sources
Helixi193 – 1964Combined sources
Helixi200 – 2078Combined sources
Helixi211 – 2177Combined sources
Beta strandi228 – 2303Combined sources
Beta strandi233 – 2353Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1VR0X-ray2.49A/B/C1-235[»]
ProteinModelPortaliQ97E82.
SMRiQ97E82. Positions 1-235.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ97E82.

Family & Domainsi

Sequence similaritiesi

Belongs to the ComB family.Curated

Phylogenomic databases

eggNOGiENOG4108N5B. Bacteria.
COG2045. LUCA.
HOGENOMiHOG000232676.
KOiK05979.
OMAiFRATSCM.
OrthoDBiEOG6SNDT4.

Family and domain databases

Gene3Di3.90.1560.10. 1 hit.
HAMAPiMF_00490. ComB.
InterProiIPR005238. ComB-like.
IPR022995. ProB_Pase_ComB.
[Graphical view]
PfamiPF04029. 2-ph_phosp. 1 hit.
[Graphical view]
SUPFAMiSSF142823. SSF142823. 1 hit.

Sequencei

Sequence statusi: Complete.

Q97E82-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIDLIISAD DIKEEKVKNK TAVVIDMLRA TSVITTALNN GCKRVVPVLT
60 70 80 90 100
VEEALKKVKE YGKDAILGGE RKGLKIEGFD FSNSPMEYTE DVVKGKTLIM
110 120 130 140 150
TTTNGTRAIK GSETARDILI GSVLNGEAVA EKIVELNNDV VIVNAGTYGE
160 170 180 190 200
FSIDDFICSG YIINCVMDRM KKLELTDAAT TAQYVYKTNE DIKGFVKYAK
210 220 230
HYKRIMELGL KKDFEYCCKK DIVKLVPQYT NGEIL
Length:235
Mass (Da):26,144
Last modified:October 1, 2001 - v1
Checksum:iA8BFB7DF07161EBD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001437 Genomic DNA. Translation: AAK81168.1.
PIRiE97297.
RefSeqiNP_349828.1. NC_003030.1.
WP_010966508.1. NC_003030.1.

Genome annotation databases

EnsemblBacteriaiAAK81168; AAK81168; CA_C3233.
GeneIDi1119415.
KEGGicac:CA_C3233.
PATRICi32040893. VBICloAce74127_3411.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001437 Genomic DNA. Translation: AAK81168.1.
PIRiE97297.
RefSeqiNP_349828.1. NC_003030.1.
WP_010966508.1. NC_003030.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1VR0X-ray2.49A/B/C1-235[»]
ProteinModelPortaliQ97E82.
SMRiQ97E82. Positions 1-235.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272562.CA_C3233.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK81168; AAK81168; CA_C3233.
GeneIDi1119415.
KEGGicac:CA_C3233.
PATRICi32040893. VBICloAce74127_3411.

Phylogenomic databases

eggNOGiENOG4108N5B. Bacteria.
COG2045. LUCA.
HOGENOMiHOG000232676.
KOiK05979.
OMAiFRATSCM.
OrthoDBiEOG6SNDT4.

Enzyme and pathway databases

BioCyciCACE272562:GJIH-3329-MONOMER.
BRENDAi3.1.3.71. 1452.

Miscellaneous databases

EvolutionaryTraceiQ97E82.

Family and domain databases

Gene3Di3.90.1560.10. 1 hit.
HAMAPiMF_00490. ComB.
InterProiIPR005238. ComB-like.
IPR022995. ProB_Pase_ComB.
[Graphical view]
PfamiPF04029. 2-ph_phosp. 1 hit.
[Graphical view]
SUPFAMiSSF142823. SSF142823. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.

Entry informationi

Entry nameiCOMB_CLOAB
AccessioniPrimary (citable) accession number: Q97E82
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 5, 2001
Last sequence update: October 1, 2001
Last modified: December 9, 2015
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.